Article
Multidisciplinary Sciences
Liang Peng, Huarong Peng, Yu Liu, Xiao Wang, Chin-Te Hung, Zaiwang Zhao, Gang Chen, Wei Li, Liqiang Mai, Dongyuan Zhao
Summary: Multi-shelled mesoporous carbon nanospheres were synthesized using a spiral self-assembly strategy, featuring diverse pore structures achieved through continuous adjustment of surfactant amphiphilicity. These carbon nanospheres exhibit excellent electrochemical performance for potassium-ion storage.
Article
Chemistry, Physical
Ru-Xin Yang, Yi-Rong Wang, Guang-Kuo Gao, Lin Chen, Yifa Chen, Shun-Li Li, Ya-Qian Lan
Summary: This research addresses the challenges in selective production of target products in CO2RR by synthesizing Cu-based hollow spheres, allowing for precise generation of various products. The introduction of CaCO3 enables effective tuning of products from C2H4 to CH4, increasing hydrocarbon selectivity and CO2 reduction efficiency.
Article
Chemistry, Inorganic & Nuclear
Xiaoming Xie, Xiaohuan Liu, Zhiyuan Ma, He Zhao, Wen Li
Summary: Ultrathin polyoxometalate nanosheets with in-plane alignment can be constructed in aqueous solution using cationic peptides as assistance. This general approach allows the templating of different types of polyoxometalates with varying topology, size, and charges into ordered 2D nanostructures, enabling the fabrication of customizable 2D materials.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Physical
Jitendra Bahadur, Jyoti Prakash, Avik Das, Debasis Sen
Summary: This study reports the synthesis of hollow silica/titania microspheres using a one-step method, which exhibit superior photocatalytic properties and thermal stability.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Bingchen Zhang, Shuo Liu, Haochen Li, Dong Wang, Wenpei Kang, Daofeng Sun
Summary: The rational design of electrode materials is important for enhancing the performance of potassium ion storage. In this study, hydrated vanadium oxide nanosheets are encapsulated into hollow mesoporous carbon spheres to form O-d-VOH@C nanospheres. The unique structure of O-d-VOH@C nanospheres results in increased reaction kinetics and efficient volume buffer for K+ storage. Furthermore, symmetric potassium-ion capacitors using O-d-VOH@C//O-d-VOH@C exhibit a high energy density of 139.6 Wh kg(-1) at 948.3 W kg(-1) power density.
Article
Chemistry, Multidisciplinary
Javier Fonseca, Lingxin Meng, Pedro Moronta, Inhar Imaz, Cefe Lopez, Daniel Maspoch
Summary: Controlling the size of COF particles allows for the fabrication of porous photonic crystals (PhCs) with a face-centered cubic arrangement. By adsorbing species within the pores of COF particles, the Bragg reflection can be altered, allowing for the modulation of the structure and properties of the PhCs. Given the abundance of existing COFs and their diverse properties, this discovery is expected to enable the development of colloidal PhCs with unprecedented functionality.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Agronomy
John A. Raven
Summary: This paper discusses the use of quantum dots in plant biology as indicators of organic nitrogen and inorganic phosphorus uptake and distribution. It focuses on the mechanism of quantum dots entry into plants and compares their toxicity with radioactive phosphorus isotopes.
Article
Chemistry, Physical
Yinsong Si, Taoqing Huang, Huiqi Xie, Min Chen
Summary: Silica brochosome-shaped microspheres (SiO2 BMs) with high similarity to natural brochosomes have been successfully synthesized. A mechanism of droplets assembly originating from the surface charge transformation has been proposed. The synthesized BMs show excellent antiadhesion and antireflection properties, suggesting great potential in various applications.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Inorganic & Nuclear
Wanlu Liu, Chunhui Liu, Luca Pilia, Hongliang Zhang, Pascal van der Voort, Anna M. Kaczmarek, Rik Van Deun
Summary: We synthesized a co-condensed hollow ethane-bipyridine periodic mesoporous organosilica (HEt-bpy-PMO) as a host material to anchor lanthanides for developing a multifunctional chemical sensor. The luminescence properties of the developed hybrid materials were studied in detail in the solid-state and after dispersing in water. The Eu3+ or Tb3+ incorporated materials showed ions selectivity towards Cu2+, Co2+, and Fe3+ as ion sensors, and exhibited excellent acetone sensing selectivity.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Multidisciplinary
Prabhjot Singh, Satish K. Pandey, Aarzoo Grover, Rohit K. Sharma, Nishima Wangoo
Summary: Amino acids are promising for the generation of functional materials due to their bio-compatibility and thermodynamic stability. The self-assembly of all naturally occurring amino acids, with their common zwitterionic motif, demonstrates vast functional diversity. Aliphatic chain amino acids have been discovered as potential candidates for modulating phenylalanine fibril toxicity, paving the way for the design and development of simple organic molecules with inherited self-assembling properties for functional nanomaterials.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Zaiwang Zhao, Linlin Duan, Yujuan Zhao, Lipeng Wang, Junye Zhang, Fanxing Bu, Zhihao Sun, Tengsheng Zhang, Mengli Liu, Hanxing Chen, Yi Yang, Kun Lan, Zirui Lv, Lianhai Zu, Pengfei Zhang, Renchao Che, Yun Tang, Dongliang Chao, Wei Li, Dongyuan Zhao
Summary: In this study, a method for fabricating three-dimensional mesoporous N-doped carbon superstructures with controllable morphology and adjustable pore structure was reported. The superstructures possess a large hollow, spherical mesopores, and interconnected porous structure, exhibiting high accessible surface area and good underwater aerophilicity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Physical
Xiao-Fei Yu, Wen-Cui Li, You-Ren Hu, Cheng-Yu Ye, An-Hui Lu
Summary: A new synthesis approach for internal gridded hollow carbon spheres is proposed in this study, which involves constructing a silica fence around solid polymer spheres to create the desired structure. These carbon spheres show good performance as sulfur hosts for Li-S batteries.
Article
Chemistry, Physical
Jennifer L. L. Cordoza, Percival Yang-Ting Chen, Linnea R. R. Blaustein, Stella T. T. Lima, Marli F. F. Fiore, Jonathan R. R. Chekan, Bradley S. S. Moore, Shaun M. K. McKinnie
Summary: Researchers have discovered and characterized the biosynthetic pathway of guanitoxin, a neurotoxin containing a cyclic arginine derivative. By comparing the structures and activities, they have identified the amino acid residues that contribute to the catalytic mechanism. This study provides a better understanding of how nature produces cyclic arginine noncanonical amino acids and offers tools for their biocatalytic production and biological applications.
Article
Chemistry, Analytical
Anastasiya A. Blinova, Abdurasul A. Karamirzoev, Asiyat R. Guseynova, David G. Maglakelidze, Tatiana A. Ilyaeva, Batradz A. Gusov, Avetis P. Meliksetyants, Mari M. Pirumian, Maxim A. Taravanov, Maxim A. Pirogov, Dmitriy S. Vakalov, Tatiana V. Bernyukevich, Alexey A. Gvozdenko, Andrey A. Nagdalian, Andrey V. Blinov
Summary: This work presents a method for synthesizing calcium silicate nanoparticles stabilized with essential amino acids. Chemical precipitation was used to obtain CaSiO3 nanoparticles. The optimal calcium-containing precursor was determined by scanning electron microscopy, with Ca(CH3COO)(2) being identified as the best option. X-ray phase analysis revealed the presence of nanosized CaSiO3-wollastonite. The addition of amino acids did not significantly affect the morphology of the CaSiO3 samples, as observed through SEM micrographs. Computerized quantum chemical modeling suggested that CaSiO3-L-methionine configuration was the most energetically favorable. This was confirmed by IR spectroscopy.
Article
Materials Science, Multidisciplinary
Wenlong Huo, Elena Tervoort, Silvan Gantenbein, Etienne Jeoffroy, Jinlong Yang, Andre R. Studart
Summary: This study reports a cost-effective and simple process to create strong, highly porous ceramics via direct ink writing of suspensions of hollow microspheres into cellular architectures with pores at three hierarchical levels. X-ray diffraction, rheological measurements, scanning electron microscopy, and mechanical tests are conducted to thoroughly study the processing steps and morphology of the printed hierarchical porous ceramics. The presence of pores at multiple length scales significantly increases the mechanical strength of the porous structure, providing a useful platform for the manufacturing of lightweight ceramics from inexpensive and widely available feedstock materials.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Review
Chemistry, Physical
Matthias Behr, Kathirvel Ganesan
Summary: Producing synthetic biocompatible matrices that exhibit specialized flexibility, stability, and biodegradability is challenging but important for improved wound healing and biomedical applications. Synthetic chitin/chitosan matrices can provide the desired advantages, but they need to be modified to improve their properties. Bioinspired techniques such as hydrogel and aerogel can be used to improve synthetic chitin/chitosan matrices by borrowing ideas from the natural molecular toolbox.
Article
Immunology
Antonio Hrvat, Mathias Schmidt, Martin Obholzer, Sonja Benders, Sebastian Kollenda, Peter A. Horn, Matthias Epple, Sven Brandau, Nina Mallmann-Gottschalk
Summary: The study explores the effects of different CaP-NPs on the anti-tumor activity of natural killer (NK) cells. Aggregated CaP-NPs can activate NK cell degranulation and impair antibody-dependent cellular cytotoxicity (ADCC). However, when properly dissolved, they do not cause substantial activation. Functionalized CaP-NPs coupled with therapeutic antibodies maintain high levels of ADCC activity.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Foteini Machla, Ioannis Angelopoulos, Matthias Epple, Maria Chatzinikolaidou, Athina Bakopoulou
Summary: This systematic review evaluates the application of potential therapeutic signaling molecules on dentin-pulp complex and pulp tissue regeneration in animal studies. The results highlight the important role of signaling molecules in dentin/pulp regeneration and the need for further research to determine more efficient combinations.
Article
Chemistry, Multidisciplinary
Roy Pattipeiluhu, Gabriela Arias-Alpizar, Gem Basha, Karen Y. T. Chan, Jeroen Bussmann, Thomas H. Sharp, Mohammad-Amin Moradi, Nico Sommerdijk, Edward N. Harris, Pieter R. Cullis, Alexander Kros, Dominik Witzigmann, Frederick Campbell
Summary: Lipid nanoparticles (LNPs) are a leading nonviral technology for delivering exogenous RNA to target cells. This study designed a novel LNP-based messenger RNA (mRNA) delivery platform that preferentially targets hepatic reticuloendothelial system (RES) cells. The RES-targeted LNPs significantly enhance mRNA expression in the liver, providing opportunities for treating liver-specific and systemic diseases.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Inorganic & Nuclear
Oliver Wetzel, Oleg Prymak, Kateryna Loza, Nina Gumbiowski, Marc Heggen, Peter Bayer, Christine Beuck, Claudia Weidenthaler, Matthias Epple
Summary: Ultrasmall nanoparticles of platinum group metal oxides were synthesized using alkaline hydrolysis and stabilized with tripeptide glutathione. Their size, oxidation state, and chemical composition were measured and determined using various techniques.
INORGANIC CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Yurii Sharkeev, Anna Eroshenko, Elena Legostaeva, Zhanna Kovalevskaya, Olga Belyavskaya, Margarita Khimich, Matthias Epple, Oleg Prymak, Viktoriya Sokolova, Qifang Zhu, Zeming Sun, Hongju Zhang
Summary: This paper presents studies on the microstructure, mechanical properties, and biocompatibility of bioinert titanium, zirconium, and niobium alloys in their nanostructured (NS) and ultrafine-grained (UFG) states. The two-step severe plastic deformation (SPD) method combined with annealing was used to form the UFG structure, which resulted in significant improvements in the mechanical characteristics of the alloys. The alloys also demonstrated good cell adhesion and viability in cell culture experiments.
Review
Chemistry, Multidisciplinary
Joachim Enax, Frederic Meyer, Erik Schulze zur Wiesche, Matthias Epple
Summary: Calcium and phosphate are essential nutrients for bone and teeth growth, as well as for other biochemical purposes. Calcium phosphates, including hydroxyapatite and tricalcium phosphate, are generally safe as food additives since they dissolve in the stomach and are easily absorbed by the body.
Article
Chemistry, Multidisciplinary
Robin H. M. van der Meijden, Deniz Daviran, Luco Rutten, X. Frank Walboomers, Elena Macias-Sanchez, Nico Sommerdijk, Anat Akiva
Summary: Osteons are cylindrical structures composed of layers of mineralized collagen fibrils, called lamellae, which make up the main organizational components of human compact bone. Recent in vitro studies question the involvement of cells in matrix mineralization and suggest that it may be driven solely by interactions between minerals and extracellular matrix. Cell-free in vitro systems have demonstrated the complete multiscale reconstruction of the osteon's 3D structure and composition, and have been explored as realistic models for studying matrix-controlled mineralization processes. Raman and electron microscopy indicate that glycosaminoglycans play a more significant role in matrix-mineral interactions than previously assumed, and collagen organization is influenced by its interaction with developing minerals.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Valentina Carotti, Wouter H. van Megen, Juan P. Rigalli, Eric R. Barros, Vera Sommers, Luco Rutten, Nico Sommerdijk, Dorien J. M. Peters, Jenny van Asbeck-van der Wijst, Joost G. J. Hoenderop
Summary: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of fluid-filled cysts within the kidney due to mutations in PKD1 or PKD2. EVs released from PKD1 knockout cells can stimulate cyst growth through effects on recipient cells, indicating their potential role in intersegmental communication and cyst growth.
Article
Chemistry, Multidisciplinary
Marina Breisch, Mateusz Olejnik, Kateryna Loza, Oleg Prymak, Nina Rosenkranz, Juergen Buenger, Christina Sengstock, Manfred Koeller, Goetz Westphal, Matthias Epple
Summary: Six types of titanium dioxide particles with different sizes, shapes, and crystal structures were prepared and characterized. The cytotoxicity and induction of reactive oxygen species of these particles were assessed, and it was found that all particles except for rutile microspheres had negligible toxicity. The rough surface of rutile microspheres induced pro-inflammatory cell reactions.
Article
Biology
Marit de Beer, Deniz Daviran, Rona Roverts, Luco Rutten, Elena Macias-Sanchez, Juriaan R. Metz, Nico Sommerdijk, Anat Akiva
Summary: A cryoCLEM workflow that combines cryo confocal microscopy with 3D cryoFIB/SEM volume imaging allows targeted imaging of tissues in their near-native state, providing high resolution imaging in the unperturbed hydrated state. However, this current method cannot be accurately applied on bulky (3D) samples such as tissues and organoids. To address this, 3D cryo-correlative imaging of large volumes is needed to close the resolution gap between cryo-light microscopy and cryoET. Here, a cryoCLEM workflow for tissues is demonstrated, correlating cryo-Airyscan confocal microscopy with 3D cryoFIB/SEM volume imaging.
COMMUNICATIONS BIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Kathrin Kostka, Matthias Epple
Summary: Calcium phosphate nanoparticles were modified with polyethyleneimine or carboxymethylcellulose and coated with a silica shell terminated with azide or alkyne groups. These particles were then covalently functionalized with proteins or gold nanoparticles using click chemistry. The functionalized particles showed good dispersibility in water, were easily taken up by cells, and were not cytotoxic.
CHEMISTRY-SWITZERLAND
(2023)
Article
Chemistry, Multidisciplinary
Negar Hassani Besheli, Martijn Martens, Elena Macias-Sanchez, Jos Olijve, Fang Yang, Nico Sommerdijk, Sander C. G. Leeuwenburgh
Summary: Through time-resolved analysis and visualization, we elucidated the formation mechanism of gelatin nanoparticles (GNPs), with the ability to precisely control their physicochemical and biofunctional properties by manipulating gelatin molecular weight and type of desolvating agent.
Article
Dentistry, Oral Surgery & Medicine
Jana Storsberg, Kateryna Loza, Matthias Epple
Summary: This study investigated the uptake of fluoride in tooth mineral when immersed in fluoride-containing solutions with different pH levels. The results showed that there was no significant increase in fluoride content when teeth were immersed in a 250 ppm fluoride solution at neutral or acidic pH values. In contrast, immersion in a 1-molar fluoride solution led to a significant increase in fluoride concentration.
Article
Dentistry, Oral Surgery & Medicine
Matthias Epple, Joachim Enax, Frederic Meyer
Summary: Dental erosion is a common problem caused by acid attack, but the protective effect of fluorides is limited.
