Article
Polymer Science
Tao Jiang, Saeed Zajforoushan Moghaddam, Esben Thormann
Summary: A facile method was developed to fabricate polyelectrolyte multilayer (PEM) films with a chemically modifiable outer surface by cross-linking and surface modification, enabling the tuning of film properties.
Article
Pharmacology & Pharmacy
Yan Yang, Yingying Xu, Sainan Wei, Weiguang Shan
Summary: Selective laser sintering (SLS) is used to prepare 3D printlets for tissue engineering and personalized implants. The printability of oral solid preparations was evaluated using a low energy laser, finding that yellow drugs and tartrazine lake can enhance printability. Increasing laser energy density improves printing efficiency but reduces accuracy, with different drugs having different printing mechanisms.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2021)
Article
Biophysics
Qing Feng Yao, Qiu Yan Zhu, Zhen Qi Bu, Qing Yu Liu, Min Xia Quan, Wei Tao Huang
Summary: This study demonstrates the construction of DNA nanosensing systems based on CoOOH nanosheets for tunable detection and valence distinction of metal ions, as well as molecular crypto-steganography. By utilizing molecular diversity and specific recognition, these systems can be used as doubly cryptographic and steganographic systems for information encoding, encryption, and hiding, while also improving metal ion selectivity.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biochemistry & Molecular Biology
Hyejoong Jeong, Taihyun Kim, Taeshik Earmme, Jinkee Hong
Summary: A method for accelerating nitric oxide (NO) release from multilayered nanofilms has been developed for facilitating antibacterial activity, showing a correlation between the NO release rate and the antibacterial effect.
Article
Biochemistry & Molecular Biology
Fatemeh Ajalloueian, Shadi Asgari, Priscila R. Guerra, Clara I. Chamorro, Oleksii Ilchenco, Sara Piqueras, Magdalena Fossum, Anja Boisen
Summary: Loading antibiotics into nanofibers is a promising approach for drug delivery, providing stable antibacterial properties and prolonged drug release. This study successfully demonstrated the effectiveness of loading Amoxicillin into Pullulan nanofibers in terms of antibacterial properties and storage time.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Physical
Genghua Yan, Bangqi Jiang, Yao Xiao, Chuanxi Zhao, Ye Yuan, Zongcun Liang
Summary: Lead-free Cs2AgBiBr6 double-perovskite material shows promise as a replacement for hybrid perovskite in optoelectronic devices, with the introduction of alkali metal ions significantly improving film quality and photoresponse performance. High-quality Rb0.1Cs1.9AgBiBr6 films and self-powered Rb+-doped Cs2AgBiBr6 photodetectors with enhanced performance have been successfully fabricated, indicating a new route for flexible Cs2AgBiBr6 optoelectronic devices.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Analytical
Yu-Syuan Lin, Zong-Yu Yang, Anisha Anand, Chih-Ching Huang, Huan-Tsung Chang
Summary: This study successfully synthesized hydrophobic carbon dots (TO-CDs) and explored their applications in detecting sodium copper chlorophyllin (SCC) and Cu2+ ions. TO-CDs exhibited good detection performance and selectivity toward SCC and Cu2+ ions. These findings are of great significance for the rapid screening of Cu2+ ions in environmental samples and SCC in foods.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Applied
J. N. Saucedo-Zuniga, S. Sanchez-Valdes, E. Ramirez-Vargas, L. Guillen, L. F. Ramos-deValle, A. Graciano-Verdugo, J. A. Uribe-Calderon, M. Valera-Zaragoza, T. Lozano-Ramirez, J. A. Rodriguez-Gonzalez, J. J. Borjas-Ramos, J. D. Zuluaga-Parra
Summary: This study focuses on the preparation and characterization of a multilayer film reservoir with clay/essential oil composites for aroma-controlled release. Two types of clays and essential oils were analyzed, with MMT clay showing higher adsorption and interaction. The multilayer film encapsulated clay/EO composites showed continuous aroma release, indicating potential applications in pest control and food packaging.
MICROPOROUS AND MESOPOROUS MATERIALS
(2021)
Article
Pharmacology & Pharmacy
Pierre Carmona, Jens Poulsen, Jan Westergren, Torben Nilsson Pingel, Magnus Roding, Eileen Lambrechts, Herlinde De Keersmaecker, Kevin Braeckmans, Aila Sarkka, Christian von Corswant, Eva Olsson, Niklas Loren
Summary: This study investigated the formation and properties of multilayer ethylcellulose/hydroxypropylcellulose films by simulating the industrial process. The results showed that the porosity and structure of the films were influenced by the ratio of EC/HPC and spin speed.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Optics
Feng Wu, Yang Long, Hongju Li, Ying Chen, Meiyan Pan, Xiaohu Wu
Summary: A frequency-tunable ENZ metamaterial based on a subwavelength dielectric-graphene multilayer structure has been designed for terahertz frequencies, with the ENZ frequency dynamically tuned by gate voltage applied to graphene. Experimental results show that only incident lights close to normal incidence can propagate through the structure, indicating potential application prospects in tunable highly directive antennas.
Article
Materials Science, Multidisciplinary
Yong Li, Xiaxia Cui, Mengwei Tian, Guangcheng Wang, Xihong Hao
Summary: This study prepared an all-inorganic flexible ferroelectric thin film by sol-gel method, showing excellent photovoltaic stability and optically tunable resistive switching behavior. The photovoltaic effect modulates the energy band structure, leading to an increased ON/OFF ratio of resistance, providing a promising route for the development of multifunctional flexible photo-electrical materials.
Article
Chemistry, Multidisciplinary
Wen-Zhi Wang, Li-Bo Huang, Shao-Ping Zheng, Emilie Moulin, Odile Gavat, Mihail Barboiu, Nicolas Giuseppone
Summary: A hydrophobic light-driven rotary motor functionalized with two 18-crown-6 macrocycles has been shown to form selective alkali ion channels in phospholipid bilayers, with a significantly accelerated ion transport mechanism under light irradiation attributed to the out-of-equilibrium actuation dynamics of the motors.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Nanoscience & Nanotechnology
Yi Sun, Xuanzhe Liu, Yu Zhu, Yue Han, Junjie Shen, Bingbo Bao, Tao Gao, Junqing Lin, Tengli Huang, Jia Xu, Yimin Chai, Xianyou Zheng
Summary: The study developed a tunable Co-ion controlled release hydrogel by incorporating eIm/ZIF-67 into GelMA, achieving a sustained release of Co ions and promoting angiogenesis and osteogenic differentiation. The nanocomposite hydrogel showed therapeutic potential as a powerful proangiogenic/osteogenic agent for bone defect treatment, exhibiting enhanced bone formation and neovascularization abilities with good biocompatibility in vivo.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Dong Liu, Kangning Zhang, Fengjing Liu, Yanxue Yin, Xiao Feng, Chengcheng Miao, Ming Chen, Xinming Zhuang, Xiaotao Hao, Zai-xing Yang
Summary: In this study, CsSnBr3 films with controlled grain boundaries and surfaces were successfully prepared using a solid-source chemical vapor deposition method. The increase in grain size of CsSnBr3 films results in reduced grain boundaries. Photodetectors based on CsSnBr3 films with decreased grain boundaries exhibit excellent performance and fast response times. This work provides insights for growing high-quality perovskite films with controlled grain boundaries and surfaces for next-generation high-performance photoelectronic devices.
ADVANCED MATERIALS INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Muhammad Waqas Shabbir, Michael N. Leuenberger
Summary: This paper introduces a spectrally selective infrared (IR) photodetector based on nanopatterned multilayer graphene intercalated with FeCl3. By utilizing localized surface plasmons (LSPs) and an optical cavity, the absorption rate is significantly increased, resulting in ultrafast response time and high detectivity through the photothermoelectric effect.
Article
Biophysics
Huiran Yang, Benrui Weng, Sijia Liu, Nana Kang, Jiabing Ran, Zhangshuang Deng, Huimin Wang, Changying Yang, Fuan Wang
Summary: In this study, we constructed an acid-improved DNAzyme-based isothermal enzyme-free concatenated DNA circuit for miRNA detection. The method achieved significantly reduced background and improved signal-to-noise ratio through catalyzed hairpin assembly (CHA) and hybridization chain reaction (HCR).
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
Yuehan Zhang, Shuai Hao, Xiaoxuan Sun, He Zhang, Qian Ma, Junfeng Zhai, Shaojun Dong
Summary: This work presents a self-powered glucose biosensor (SPGB) consisting of a copper anode and a glucose oxidase/Prussian blue/ITO biocathode. The SPGB is capable of flow sensing glucose with a wide linear detection range, high sensitivity, low detection limit, and satisfactory performance in determining glucose in juices.
Article
Chemistry, Multidisciplinary
Qiong Wu, Lei Yang, Lingling Xie, Jinhua Shang, Shizhen He, Jing Liu, Fuan Wang
Summary: This research presents a multilayer nonenzymatic catalytic DNA circuits-based aptasensing system, which enables in situ imaging of bioactive molecules in living mice. The aptasensing system shows high sensitivity, accuracy, and adaptability, making it suitable for analyzing various bioactive molecules.
Article
Nanoscience & Nanotechnology
Yushi Wang, Yingying Chen, Yeqing Wan, Chen Hong, Jinhua Shang, Fengzhe Li, Xiaoqing Liu, Fuan Wang
Summary: This study proposes an autocatalytic hybridization system that combines hybridization chain assembly and catalytic DNA assembly for highly efficient positive feedback amplification. The system allows sensitive detection of polynucleotide kinase and has the potential for accurate monitoring and screening in vitro and in biological samples.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biochemistry & Molecular Biology
Rongbing Li, Xiaoxuan Sun, Yujia Jiang, Ling Liu, Yunhui Li, Dengbin Yu, Jianwei Zhu, Shaojun Dong
Summary: In this study, a colorimetric biosensor based on the rapid color change of E. coli and BQ was introduced for water toxicity evaluation. The biosensor showed a dose-dependent response, with IC20 values for Cu2+ and Hg2+ obtained based on RGB values. It has the potential to quickly detect the toxicity of Cu2+ and Hg2+ in water.
BIOELECTROCHEMISTRY
(2023)
Article
Engineering, Environmental
Jialing Hu, Zhiqiao Zou, Fengye Mo, Xue Lin, Yun Zhao, Tianhui Shi, Fuan Wang, Xiaoqing Liu
Summary: A DNA prodrug-laden metallo-nanoassembly has been developed for sensitive activation of DNAzymes to regulate disease genes, with enhanced gene cleavage activity and improved drug stability.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Jianguo Zhao, He Zhang, Xiaoxuan Sun, Shuai Hao, Panpan Zhao, Xinyang Zhu, Shaojun Dong
Summary: This paper reports an integrated bio-photoelectrochemical system based on photo-enzyme coupled catalysis for glucose oxidation and hydrogen peroxide production. The proposed system shows excellent performance in terms of maximum power output and efficient H2O2 accumulation, expanding the functional versatility of green energy devices.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Analytical
Zhixuan Yu, Jiaxin Zhang, Jinxing Chen, Liyi Zhao, Dengbin Yu, Ling Liu, Shaojun Dong
Summary: fi-D-Glucuronidase (GUS) plays a crucial role in clinical treatment assessment and environmental monitoring. However, current GUS detection tools have limitations in terms of pH continuity and diffusion. In this study, a novel GUS recognition tool called ERNathG was developed, which addressed these issues by utilizing pH-matching and endoplasmic reticulum-anchoring strategies. ERNathG enabled continuous and anchored GUS detection without pH adjustment, demonstrating superior properties compared to commonly used commercial molecules.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Physical
Long Pang, Zhiwei Zhao, Xian-Yin Ma, Wen-Bin Cai, Limin Guo, Shaojun Dong, Chuntai Liu, Zhangquan Peng
Summary: Researchers have developed a novel analytical method that combines differential electrochemical mass spectrometry and attenuated total reflection surface enhanced infrared absorption spectroscopy to simultaneously detect deposited and volatile interface species. This technique is particularly suitable for non-aqueous, electrolyte-based energy devices. By applying this method in lithium-ion and lithium-oxygen batteries, they obtained valuable reaction mechanisms. Overall, this coupled and complementary technique provides important insights into the interfacial electrochemistry of energy storage materials and is expected to generate significant interest in the electrochemistry community and beyond.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Chemistry, Physical
Panpan Zhao, Xiaoxuan Sun, Shuai Hao, Yuehan Zhang, Jinxing Chen, He Zhang, Shaojun Dong
Summary: In this work, rhodium single-atom nanozymes (Rh SANs) were designed to mimic the function of natural glucose oxidase (GOD) for glucose oxidation. The Rh SANs demonstrated the same biocatalytic mechanism and electrocatalytic path as natural GOD. By coupling a bilirubin oxidase biocathode, a Rh SANs-based glucose/O2 enzymatic biofuel cell (EBFC) was developed with a significantly enhanced power density compared to a natural GOD-based EBFC. This device not only accelerates the development of nanozymes but also paves avenues for powering portable and wearable devices.
ACS ENERGY LETTERS
(2023)
Review
Chemistry, Multidisciplinary
Wei Xu, Feifei Hu, Jiajing Li, Jinhua Shang, Xiaoqing Liu, Yan Zeng, Qiong Wu, Fuan Wang
Summary: This article provides an overview of recent advances in stimuli-responsive DNA devices that can respond to a variety of external triggers. These triggers include physical stimuli, chemical stimuli, and biological stimuli, and the DNA devices have controllable nanofabrication and biomedical applications.
SCIENCE CHINA-CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Siyuan Wang, Jinhua Shang, Bingyue Zhao, Huimin Wang, Changying Yang, Xiaoqing Liu, Fuan Wang
Summary: This Review summarizes the important role of isothermal enzyme-free nucleic acid amplification in biosensing, describes the mechanisms of entropy-driven reaction, hybridization chain reaction, catalytic hairpin assembly, and DNAzyme, and comprehensively discusses their recent applications as biosensors. It also discusses the current problems and developments in these DNA circuits.
Review
Chemistry, Analytical
Siyuan Wang, Yaqi Liu, Jinhua Shang, Huimin Wang, Changying Yang, Xiaoqing Liu, Fuan Wang
Summary: This article provides a comprehensive review of DNAzymes, including their in vitro selection methods and activity regulation strategies. The recent advances in DNAzyme-based biosensors and therapeutic applications are summarized, along with discussion on current challenges and future development.
ANALYSIS & SENSING
(2023)
Article
Nanoscience & Nanotechnology
Yongqin Liu, Liang Huang, Youxing Fang, Xinyang Zhu, Jianli Nan, Shaojun Dong
Summary: In this study, a novel catalyst was designed through interfacial engineering, leading to enhanced yield rate and Faradaic efficiency of ammonia production. This provides new insights into electrocatalytic nitrogen reduction.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Weiwei Wu, Liang Huang, Xinyang Zhu, Jinxing Chen, Daiyong Chao, Minghua Li, Shuangli Wu, Shaojun Dong
Summary: This article investigates the inhibitory effect of nanozymes and the advantages of single-atom Fe-N-C nanozymes in mechanism research. The study finds that a common analgesic-antipyretic drug inhibits the oxidase-like activity of Fe-SANs in a reversible mixed-inhibition manner. Additionally, a calorimetric method for drug detection based on nanozyme inhibition is proposed.