Multi-stimuli-triggered release of charged dye from smart PEGylated nanogels containing gold nanoparticles to regulate fluorescence signals

Polyion complex nanoparticles based on 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt (PSA) and stimuli-responsive PEGylated nanogels composed of PEG tethered chains and a cross-linked poly[2-(N,N-diethylamino) ethyl methacrylate] gel core containing gold nanoparticles showed a remarkable regulation of the fluorescence signal synchronizing with the multi-stimuli-triggered release of the PSA in response to pH, temperature and light.