Navigating Breast Cancer: Axon Guidance Molecules as Breast Cancer Tumor Suppressors and Oncogenes

Plasma netrin-1 is a diagnostic biomarker of human cancers

(2011) Ganesan Ramesh et al.   BIOMARKERS

SLIT/ROBO1 Signaling Suppresses Mammary Branching Morphogenesis by Limiting Basal Cell Number

(2011) Hector Macias et al.   DEVELOPMENTAL CELL

Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism

(2010) Nao Hiramoto-Yamaki et al.   JOURNAL OF CELL BIOLOGY

EphrinB reverse signaling in cell-cell adhesion

(2010) Hyun-Shik Lee et al.   Cell Adhesion & Migration

Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer

(2009) Tomoko Fujikane et al.   BREAST CANCER RESEARCH AND TREATMENT

Interfering with multimerization of netrin-1 receptors triggers tumor cell death

(2009) F Mille et al.   CELL DEATH AND DIFFERENTIATION

The Cleavage of Semaphorin 3C Induced by ADAMTS1 Promotes Cell Migration

(2009) Cary Esselens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Mammary Gland Branching Morphogenesis by EphA2 Receptor Tyrosine Kinase

(2009) David Vaught et al.   MOLECULAR BIOLOGY OF THE CELL

EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells

(2009) B P Fox et al.   ONCOGENE

Deubiquitinating enzyme USP33/VDU1 is required for Slit signaling in inhibiting breast cancer cell migration

(2009) J. Yuasa-Kawada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autocrine semaphorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cells

(2008) Hongjie Pan et al.   BREAST CANCER RESEARCH AND TREATMENT

Semaphorin 3B Inhibits the Phosphatidylinositol 3-Kinase/Akt Pathway through Neuropilin-1 in Lung and Breast Cancer Cells

(2008) E. Castro-Rivera et al.   CANCER RESEARCH

SLITs Suppress Tumor Growth In vivo by Silencing Sdf1/Cxcr4 within Breast Epithelium

(2008) R. Marlow et al.   CANCER RESEARCH

Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers – Results of a large scale microarray analysis

(2008) Achim Rody et al.   EUROPEAN JOURNAL OF CANCER

Netrin-4 regulates angiogenic responses and tumor cell growth

(2008) Mariana Nacht et al.   EXPERIMENTAL CELL RESEARCH

Slit-2 Induces a Tumor-suppressive Effect by Regulating β-Catenin in Breast Cancer Cells

(2008) Anil Prasad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

(2008) Dana M. Brantley-Sieders et al.   JOURNAL OF CLINICAL INVESTIGATION

The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment

(2008) Charlotte Rolny et al.   JOURNAL OF EXPERIMENTAL MEDICINE

EphrinB1 controls cell–cell junctions through the Par polarity complex

(2008) Hyun-Shik Lee et al.   NATURE CELL BIOLOGY

Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor

(2008) J Wykosky et al.   ONCOGENE

Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B

(2008) E. Lejmi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer

(2008) J. Fitamant et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA