期刊
JOURNAL OF MAGNETIC RESONANCE IMAGING
卷 29, 期 2, 页码 350-356出版社
WILEY
DOI: 10.1002/jmri.21651
关键词
focal pancreatitis; pancreatic cancer; diffusion-weighted MRI; ADC; normal pancreas
Purpose: To compare diffusion-weighted imaging (DWI) findings and the apparent diffusion coefficient (ADC) values of pancreatic cancer (PC), mass-forming focal pancreatitis (FP), and the normal pancreas. Materials and Methods: DWI (b = 0 and 600 seconds/mm(2)) findings of 14 patients with mass-forming FP proven by histopathology and or clinical follow-up. 10 patients with histopathologically-proven PC, and 14 subjects with normal pancreatic exocrine function and normal imaging findings were retrospectively evaluated. ADC values of the masses, the remaining pancreas, and the normal pancreas were measured. Results: On b = 600 seconds/mm(2) DWI, mass-forming FP was visually indistinguishable from the remaining pancreas whereas PC was hyperintense relative to the remaining pancreas. The mean ADC value of PC (1.46 +/- 0.18 mm(2)/second) was significantly lower than the remaining pancreas (2.11 +/- 0.32 x 10(-3) mm(2)/second; P < 0.0001). mass-forming FP (2.09 +/- 0.18 x 10(-3) mm(2)/second; P < 0.0001), and pancreatic gland in the control group (1.78 +/- 0.07 x 10(-3) mm(2)/second; P < 0.0005). There was no significant difference of ADC values between the mass-forming focal pancreatitis and the remaining pancreas (2.03 +/- 0.2 x 10(-3) mm(2)/second: P > 0.05). Conclusion: Differences on DWI may help to differentiate PC, mass-forming FP, and normal pancreas from each other.
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