Vaginal Toxic Shock Reaction Triggering Desquamative Inflammatory Vaginitis

Objective. The study aimed to report 2 cases of desquamative inflammatory vaginitis associated with toxic shock syndrome toxin 1 (TSST-1) producing Staphylococcus aureus strains. Materials and Methods. Case report of 2 patients, 1 with an acute and 1 with a chronic presentation, diagnosed with desquamative inflammatory vaginitis on the basis of clinical findings and wet mount microscopy. Pretreatment and posttreatment vaginal bacterial and yeast cultures were obtained. Results. Pretreatment vaginal bacterial cultures from both patients grew TSST-1 producing S. aureus. Subsequent vaginal bacterial culture results after oral antibiotic therapy were negative. Conclusions. Desquamative inflammatory vaginitis may be triggered through TSST-1 mediated vaginal toxic shock reaction.