Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture

Oxysterols are allosteric activators of the oncoprotein Smoothened

(2012) Sigrid Nachtergaele et al.   Nature Chemical Biology

Oxysterols as non-genomic regulators of cholesterol homeostasis

(2012) Agata A. Bielska et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Axonopathy is a compounding factor in the pathogenesis of Krabbe disease

(2011) Ludovico Cantuti Castelvetri et al.   ACTA NEUROPATHOLOGICA

Membrane Biophysics and Mechanics in Alzheimer's Disease

(2010) Xiaoguang Yang et al.   MOLECULAR NEUROBIOLOGY

Weekly Cyclodextrin Administration Normalizes Cholesterol Metabolism in Nearly Every Organ of the Niemann-Pick Type C1 Mouse and Markedly Prolongs Life

(2010) Charina M Ramirez et al.   PEDIATRIC RESEARCH

Activation of Membrane Cholesterol by 63 Amphipaths

(2009) Yvonne Lange et al.   BIOCHEMISTRY

Cyclodextrin overcomes the transport defect in nearly every organ of NPC1 mice leading to excretion of sequestered cholesterol as bile acid

(2009) Benny Liu et al.   JOURNAL OF LIPID RESEARCH

Psychosine Accumulates in Membrane Microdomains in the Brain of Krabbe Patients, Disrupting the Raft Architecture

(2009) A. B. White et al.   JOURNAL OF NEUROSCIENCE

Psychosine-induced alterations in peroxisomes of twitcher mouse liver

(2008) Miguel Agustin Contreras et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Side Chain Oxygenated Cholesterol Regulates Cellular Cholesterol Homeostasis through Direct Sterol-Membrane Interactions

(2008) Sarah E. Gale et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of AMPK in psychosine mediated effects on oligodendrocytes and astrocytes: implication for Krabbe Disease

(2008) Shailendra Giri et al.   JOURNAL OF NEUROCHEMISTRY

ent-Steroids: Novel tools for studies of signaling pathways

(2008) Douglas F. Covey   STEROIDS