A novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes

Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity

(2012) Jorg Kotzka et al.   PLoS One

The role of lipid droplets in metabolic disease in rodents and humans

(2011) Andrew S. Greenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes

(2011) Minoru Ito et al.   JOURNAL OF LIPID RESEARCH

Suppression of FoxO1/cell death-inducing DNA fragmentation factor α-like effector A (Cidea) axis protects mouse β-cells against palmitic acid-induced apoptosis

(2011) Naoki Omae et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adipocyte Hypertrophy, Fatty Liver and Metabolic Risk Factors in South Asians: The Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE)

(2011) Sonia S. Anand et al.   PLoS One

Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective

(2010) Roger HF Wong et al.   CURRENT OPINION IN PHARMACOLOGY

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Fat-specific Protein 27 Undergoes Ubiquitin-dependent Degradation Regulated by Triacylglycerol Synthesis and Lipid Droplet Formation

(2010) Zongqian Nian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential roles of CIDEA and CIDEC in insulin-induced anti-apoptosis and lipid droplet formation in human adipocytes

(2010) Minoru Ito et al.   JOURNAL OF LIPID RESEARCH

Protein kinase Cbeta mediates hepatic induction of sterol-regulatory element binding protein-1c by insulin

(2010) Takashi Yamamoto et al.   JOURNAL OF LIPID RESEARCH

Insulin Enhances Post-translational Processing of Nascent SREBP-1c by Promoting Its Phosphorylation and Association with COPII Vesicles

(2009) Chandrahasa R. Yellaturu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin Enhances the Biogenesis of Nuclear Sterol Regulatory Element-binding Protein (SREBP)-1c by Posttranscriptional Down-regulation of Insig-2A and Its Dissociation from SREBP Cleavage-activating Protein (SCAP)·SREBP-1c Complex

(2009) Chandrahasa R. Yellaturu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of NMDA receptor–dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries

(2009) Changiz Taghibiglou et al.   NATURE MEDICINE

Silencing Jnk1 and Jnk2 accelerates basal lipolysis and promotes fatty acid re-esterification in mouse adipocytes

(2008) A. V. Rozo et al.   DIABETOLOGIA

SREBPs: physiology and pathophysiology of the SREBP family

(2008) Hitoshi Shimano   FEBS Journal

Fat-specific Protein 27 Regulates Storage of Triacylglycerol

(2008) Pernille Keller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets

(2008) Naonobu Nishino et al.   JOURNAL OF CLINICAL INVESTIGATION

Adipocyte metabolism and obesity: Fig. 1.

(2008) Alan D. Attie et al.   JOURNAL OF LIPID RESEARCH

siRNA screening reveals JNK2 as an evolutionary conserved regulator of triglyceride homeostasis

(2008) Vinciane Grimard et al.   JOURNAL OF LIPID RESEARCH

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Up-Regulation of Mitochondrial Activity and Acquirement of Brown Adipose Tissue-Like Property in the White Adipose Tissue of Fsp27 Deficient Mice

(2008) Shen Yon Toh et al.   PLoS One

SREBPs: the crossroads of physiological and pathological lipid homeostasis

(2008) Rajendra Raghow et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM