Single nucleotide polymorphisms in theFADSgene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios

Does genetic variation in the Δ6-desaturase promoter modify the association between α-linolenic acid and the prevalence of metabolic syndrome?

(2009) Hong Truong et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

A commonFADS2promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1

(2009) E. Lattka et al.   JOURNAL OF LIPID RESEARCH

Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance

(2009) Eva Warensjö et al.   Lipids in Health and Disease

Genome-Wide Association Study of Plasma Polyunsaturated Fatty Acids in the InCHIANTI Study

(2009) Toshiko Tanaka et al.   PLoS Genetics

A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia

(2009) Christopher L. Plaisier et al.   PLoS Genetics

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes

(2008) Peter Rzehak et al.   BRITISH JOURNAL OF NUTRITION

Changes in Insulin Resistance and Cardiovascular Risk During Adolescence

(2008) Antoinette Moran et al.   CIRCULATION

Δ6-Desaturase (FADS2) deficiency unveils the role of ω3- and ω6-polyunsaturated fatty acids

(2008) Wilhelm Stoffel et al.   EMBO JOURNAL

Design and implementation of the Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study

(2008) L A Moreno et al.   INTERNATIONAL JOURNAL OF OBESITY

Genetic Variants of the FADS1 FADS2 Gene Cluster Are Associated with Altered (n-6) and (n-3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation

(2008) Lin Xie et al.   JOURNAL OF NUTRITION

SNPs of the FADS Gene Cluster are Associated with Polyunsaturated Fatty Acids in a Cohort of Patients with Cardiovascular Disease

(2008) Giovanni Malerba et al.   LIPIDS

Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

(2008) Chiara Sabatti et al.   NATURE GENETICS

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts

(2008) Yurii S Aulchenko et al.   NATURE GENETICS