Article
Endocrinology & Metabolism
Lei Wu, Yan Zhang, Hong Zhao, Guodong Rong, Peijun Huang, Fang Wang, Ting Xu
Summary: This study found that APOE gene polymorphisms are associated with CAD with or without T2DM and have an influence on lipid profiles in both T2DM and CAD patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Pharmacology & Pharmacy
Wenbing Ma, Xiaodong Ren, Liting Zhang, Haiyan Dong, Xiaoyun Lu, Weiyi Feng
Summary: This study showed that the ε4 allele is closely related to CAD risk in the northwest Chinese population, especially in elderly patients. Additionally, carriers of the ε4 allele had significantly different levels of lipoproteins and were associated with an increased risk of CAD.
PHARMACOGENOMICS & PERSONALIZED MEDICINE
(2021)
Article
Medical Laboratory Technology
Qinghua Liu, Heming Wu, Zhikang Yu, Qingyan Huang, Zhixiong Zhong
Summary: The study found that the APOE epsilon 4 allele may be associated with susceptibility to CAD in the southern Chinese Hakka population. It indicated that the APOE SNPs rs429358 and rs7412 are associated with CAD, but not the SLCO1B1 gene SNPs rs2306283 and rs4149056.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2021)
Article
Nutrition & Dietetics
Mina Darand, Amin Salehi-Abargouei, Mohammad Yahya Vahidi Mehrjardi, Awat Feizi, Seyed Mustafa Seyedhossaini, Gholamreza Askari
Summary: This study investigated the interaction between PON1 rs662 polymorphism and vitamin C/E intake on CAD severity and lipid profile. The results showed that R allele carriers had lower HDL-C levels and higher LDL-C levels when they had lower vitamin C intake. Vitamin C intake was also associated with the risk of high total cholesterol and low-density lipoprotein cholesterol.
FRONTIERS IN NUTRITION
(2023)
Article
Pharmacology & Pharmacy
Rui-Bing Niu, Xiao-Xian Dong, Li-Ping Guo, Li Pan, Yue-Qin Hai, Xiao-Xiao Chen, Bao-Sheng Duan
Summary: The study found that the SLCO1B *1a/*15 genotype, ApoE epsilon 3/epsilon 3 genotype, and epsilon 3 allele reduce the risk of coronary disease in the Mongolian population, acting as protective genes, while the ApoE epsilon 4 allele increases the risk of coronary disease, serving as a risk factor for coronary disease.
CLINICAL AND EXPERIMENTAL HYPERTENSION
(2021)
Article
Immunology
Xinlin Xiong, Zonggang Duan, Haiyan Zhou, Guangwei Huang, Li Niu, Zhenhua Luo, Wei Li
Summary: This study aimed to investigate the association of Apolipoprotein A-I (APOAI) with T cell subsets and interferon-γ (IFN-γ) in patients with coronary artery disease (CAD). T cell subsets and CD3-CD56+ natural killer cells were quantified, and the serum concentrations of IFN-γ were measured. The results showed that CD4+ T cells were higher in the low-APOAI group, and high-density lipoprotein cholesterol (HDL-C) was inversely associated with CD4+ T cells and positively associated with CD8+ T cells. APOA1 and HDL-C did not correlate with fibrinogen and CRP.
IMMUNITY INFLAMMATION AND DISEASE
(2023)
Article
Medical Laboratory Technology
Tatsuya Fukase, Tomotaka Dohi, Ryota Nishio, Mitsuhiro Takeuchi, Norihito Takahashi, Yuichi Chikata, Hirohisa Endo, Shinichiro Doi, Hiroki Nishiyama, Iwao Okai, Hiroshi Iwata, Shinya Okazaki, Katsumi Miyauchi, Hiroyuki Daida, Tohru Minamino
Summary: This study examined the combined impacts of ApoA-I and renal function in patients after intervention, revealing that patients with low ApoA-I levels and K-D had the highest cumulative incidence rate of MACCE and all-cause death. ApoA-I levels and K-D status were independent predictors of MACCE and all-cause death.
CLINICA CHIMICA ACTA
(2022)
Article
Cell Biology
Raziye Akcilar, Gunduz Yumun, Zeynep Bayat, Okan Donbaloglu, Ozcan Gur, Selami Gurkan, Ozlem Arik
Summary: The study found that the vaspin rs2236242 polymorphism is associated with CAD in the Turkish population, with the TA genotype increasing the risk of CAD.
JOURNAL OF CELLULAR PHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Li Li, Gaojun Cai, Wei Lu, Feng Li, Lei Yu, Jianqiang Xiao
Summary: The study found a negative correlation between the high-density lipoprotein cholesterol (HDL-C)/apolipoprotein A-I (apoA-I) ratio and serum free triiodothyronine (FT3), as well as a significant interaction between them and the risk of coronary artery disease (CAD).
BMC CARDIOVASCULAR DISORDERS
(2021)
Article
Medicine, General & Internal
Charles F. Hayfron-Benjamin, Charlotte Mosterd, Anke H. Maitland-van der Zee, Daniel H. van Raalte, Albert G. B. Amoah, Charles Agyemang, Bert-Jan van den Born
Summary: This study found unequal associations between inflammatory biomarkers and vascular dysfunction in different ethnic groups, providing valuable insights for future research.
Article
Gastroenterology & Hepatology
Aleksandra Glapa-Nowak, Mariusz Szczepanik, Barbara Iwanczak, Jaroslaw Kwiecien, Anna Barbara Szaflarska-Poplawska, Urszula Grzybowska-Chlebowczyk, Marcin Osiecki, Marcin Dziekiewicz, Andrzej Stawarski, Jaroslaw Kierkus, Tomasz Banasiewicz, Aleksandra Banaszkiewicz, Jaroslaw Walkowiak
Summary: APOE polymorphisms are associated with the risk of developing IBD and the clinical expression of IBD, but the clinical relevance of the differences identified is rather modest.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Review
Cardiac & Cardiovascular Systems
Yongyan Song, Shujin Li, Chuan He
Summary: Activated by ligands, PPAR gamma plays a role in enhancing insulin sensitivity, promoting adipocyte differentiation, and possessing anti-atherosclerosis, anti-inflammation, and anti-oxidation properties. Polymorphisms in the PPARG gene have been associated with coronary artery disease, possibly through affecting PPARG gene expression and PPAR gamma protein function, leading to metabolic disorders and increased susceptibility to CAD.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Paul T. Jurgens, John J. Carr, James G. Terry, Jamal S. Rana, David R. Jacobs, Daniel A. Duprez
Summary: This study investigated the predictive value of abdominal aorta calcium (AAC) relative to coronary artery calcium (CAC) for cardiovascular disease (CVD) and coronary heart disease (CHD) events in Black and White early middle-aged participants. The results showed that AAC and CAC had similar predictive effects on CVD, with only CAC being able to predict CHD. Additionally, AAC was able to predict incident CVD when CAC was 0.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Medicine, General & Internal
Xingzhu Liu, Yanfei Chen, Yanfei Yang, Zhongjian Su, Feng Wang, Chenghao Zhanghuang, Yuqin Wu, Xing Zhang
Summary: This study investigated the correlation between FGA gene polymorphisms and coronary artery lesion in Kawasaki disease. The concentrations of serum MMPs and FG-α were significantly higher in KD patients, suggesting that FGA gene polymorphisms affect coronary artery lesion in children with KD.
FRONTIERS IN MEDICINE
(2023)
Article
Gastroenterology & Hepatology
Jose Carlos Rodrigues Nascimento, Lianna C. Pereira, Juliana Magalhaes C. Rego, Ronaldo P. Dias, Paulo Goberlanio B. Silva, Silvio Alencar C. Sobrinho, Gustavo R. Coelho, Ivelise Regina C. Brasil, Edmilson F. Oliveira-Filho, James S. Owen, Pierluigi Toniutto, Reinaldo B. Oria
Summary: This study aimed to determine the impact of APOE alleles on outcomes in HCV-infected patients with liver cirrhosis following orthotopic liver transplantation. The results suggest that the E4 allele may protect against progression of liver fibrosis and degree of inflammation in these patients.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Byambaa Enkhmaa, Erdembileg Anuurad, Wei Zhang, Kyoungmi Kim, Lars Berglund
Article
Endocrinology & Metabolism
Byambaa Enkhmaa, Erdembileg Anuurad, Wei Zhang, Adnan Abbuthalha, Parneet Kaur, Jasmeen Visla, Sidika Karakas, Lars Berglund
CLINICAL ENDOCRINOLOGY
(2016)
Article
Medicine, Research & Experimental
Sarah B. Garrett, Barbara A. Koenig, Arleen Brown, Jen R. Hult, Elizabeth A. Boyd, Sarah Dry, Daniel Dohan
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2015)
Review
Biochemistry & Molecular Biology
Byambaa Enkhmaa, Erdembileg Anuurad, Lars Berglund
JOURNAL OF LIPID RESEARCH
(2016)
Article
Veterinary Sciences
Byambaa Enkhmaa, Adnan Abbuthalha, Erdembileg Anuurad, Wei Zhang, Alice F. Tarantal, Lars Berglund
JOURNAL OF MEDICAL PRIMATOLOGY
(2015)
Article
Biochemical Research Methods
Sridevi Krishnan, Jincui Huang, Hyeyoung Lee, Andres Guerrero, Lars Berglund, Erdembileg Anuurad, Carlito B. Lebrilla, Angela M. Zivkovic
JOURNAL OF PROTEOME RESEARCH
(2015)
Editorial Material
Medical Laboratory Technology
Byambaa Enkhmaa, Erdembileg Anuurad, Lars Berglund
TRANSLATIONAL RESEARCH
(2015)
Review
Peripheral Vascular Disease
Prasanth Surampudi, Byambaa Enkhmaa, Erdembileg Anuurad, Lars Berglund
CURRENT ATHEROSCLEROSIS REPORTS
(2016)
Article
Endocrinology & Metabolism
Margaret R. Diffenderfer, Stefania Lamon-Fava, Santica M. Marcovina, P. Hugh R. Barrett, Julian Lel, Gregory G. Dolnikowski, Lars Berglund, Ernst J. Schaefer
METABOLISM-CLINICAL AND EXPERIMENTAL
(2016)
Editorial Material
Medical Laboratory Technology
Byambaa Enkhmaa, Erdembileg Anuurad, Lars Berglund
TRANSLATIONAL RESEARCH
(2016)
Article
Multidisciplinary Sciences
Anuurad Erdembileg, Annie Mirsoian, Byambaa Enkhmaa, Wei Zhang, Laurel A. Beckett, William J. Murphy, Lars F. Berglund
Article
Health Care Sciences & Services
Heather Young, Sheridan Miyamoto, Deborah Ward, Madan Dharmar, Yajarayma Tang-Feldman, Lars Berglund
TELEMEDICINE AND E-HEALTH
(2014)
Editorial Material
Medicine, General & Internal
Byambaa Enkhmaa, Lars Berglund
JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
Betty P. Guo, Julie Rainwater, Stacey Neves, Erdembileg Anuurad, Ted Wun, Lars Berglund
Summary: By establishing a K scholar resource platform and utilizing CTSC research resources, UC Davis has provided early career investigators with a high rate of NIH funding success.
JOURNAL OF CLINICAL AND TRANSLATIONAL SCIENCE
(2021)
Article
Hematology
Byambaa Enkhmaa, Erdembileg Anuurad, Wei Zhang, Chin-Shang Li, Robert Kaplan, Jason Lazar, Dan Merenstein, Roksana Karim, Brad Aouizerat, Mardge Cohen, Kenneth Butler, Savita Pahwa, Igho Ofotokun, Adaora A. Adimora, Elizabeth Golub, Lars Berglund
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2017)