The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies
出版年份 2018 全文链接
标题
The PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by α-PD-L1 or α-IL6 antibodies
作者
关键词
-
出版物
JOURNAL OF LEUKOCYTE BIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-07-25
DOI
10.1002/jlb.ma1217-495r
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- IL-27 regulates the adherence, proliferation, and migration of MSCs and enhances their regulatory effects on Th1 and Th2 subset generations
- (2017) Fenghuang Xu et al. IMMUNOLOGIC RESEARCH
- Dual Roles of IL-27 in Cancer Biology and Immunotherapy
- (2017) Marina Fabbi et al. MEDIATORS OF INFLAMMATION
- Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity
- (2017) Jeongsu Do et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27
- (2017) Alessandra Dondero et al. Oncotarget
- IL-6, cancer and cachexia: metabolic dysfunction creates the perfect storm
- (2017) James P. White Translational Cancer Research
- Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling
- (2017) Kristine Pettersen et al. Scientific Reports
- Interleukin-30 Promotes Breast Cancer Growth and Progression
- (2016) Irma Airoldi et al. CANCER RESEARCH
- An IL-27/Stat3 axis induces expression of programmed cell death 1 ligands (PD-L1/2) on infiltrating macrophages in lymphoma
- (2016) Hasita Horlad et al. CANCER SCIENCE
- Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling
- (2016) Andy J. Minn et al. CELL
- Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity
- (2016) Thomas R. Flint et al. Cell Metabolism
- Combinatorial immunotherapy strategies for hepatocellular carcinoma
- (2016) Maria Tagliamonte et al. CURRENT OPINION IN IMMUNOLOGY
- The untold story of IFN-γ in cancer biology
- (2016) M. Alper Kursunel et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Systemic delivery of IL-27 by an adeno-associated viral vector inhibits T cell-mediated colitis and induces multiple inhibitory pathways in T cells
- (2016) Xiaotong Zhu et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy
- (2016) Lewis Zhichang Shi et al. Nature Communications
- Proteomic analysis uncovers common effects of IFN-γ and IL-27 on the HLA class I antigen presentation machinery in human cancer cells
- (2016) Andrea Petretto et al. Oncotarget
- Immunotherapy in hepatocellular carcinoma: Primed to make a difference?
- (2015) James J. Harding et al. CANCER
- Potential clinical application of interleukin-27 as an antitumor agent
- (2015) Takayuki Yoshimoto et al. CANCER SCIENCE
- Constitutive activation of oncogenic PDGFRα-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRα signalling characteristics
- (2015) Christelle Bahlawane et al. Cell Communication and Signaling
- The biology of interleukin-27 reveals unique pro- and anti-inflammatory functions in immunity
- (2015) Samadhi Aparicio-Siegmund et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Interleukin 35: Critical regulator of immunity and lymphocyte-mediated diseases
- (2015) Charles E. Egwuagu et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity
- (2015) Kiyoshi Hirahara et al. IMMUNITY
- Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer
- (2015) Christina Twyman-Saint Victor et al. NATURE
- In situ vaccination by radiotherapy to improve responses to anti-CTLA-4 treatment
- (2015) Claire Vanpouille-Box et al. VACCINE
- IL-27 induces the expression of IDO and PD-L1 in human cancer cells
- (2015) Grazia Carbotti et al. Oncotarget
- FactoMineR: AnRPackage for Multivariate Analysis
- (2015) Sébastien Lê et al. Journal of Statistical Software
- Side Effects of Cytokines Approved for Therapy
- (2014) Brian A. Baldo DRUG SAFETY
- STAT3 Is Indispensable to IL-27-Mediated Cell Proliferation but Not to IL-27-Induced Th1 Differentiation and Suppression of Proinflammatory Cytokine Production
- (2014) T. Owaki et al. JOURNAL OF IMMUNOLOGY
- Antiproliferative Activity of IL-27 on Melanoma
- (2014) T. Yoshimoto et al. JOURNAL OF IMMUNOLOGY
- Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial
- (2014) Caroline Robert et al. LANCET
- MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
- (2014) Thomas Powles et al. NATURE
- Role of interleukin-6 in cachexia
- (2014) Aditi A. Narsale et al. Current Opinion in Supportive and Palliative Care
- Interleukin-30 Expression in Prostate Cancer and Its Draining Lymph Nodes Correlates with Advanced Grade and Stage
- (2013) Serena Di Meo et al. CLINICAL CANCER RESEARCH
- A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
- (2013) Bruno Sangro et al. JOURNAL OF HEPATOLOGY
- Expression of IL-27 by Tumor Cells in InvasCutaneous and Metastatic Melanomas
- (2013) Julie Gonin et al. PLoS One
- IL-27 in tumor immunity and immunotherapy
- (2013) Gopal Murugaiyan et al. TRENDS IN MOLECULAR MEDICINE
- Could the properties of IL-27 make it an ideal adjuvant for anticancer immunotherapy?
- (2013) Alexander Swarbrick et al. OncoImmunology
- Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1
- (2012) Kiyoshi Hirahara et al. IMMUNITY
- An Interleukin-6 Receptor-dependent Molecular Switch Mediates Signal Transduction of the IL-27 Cytokine Subunit p28 (IL-30) via a gp130 Protein Receptor Homodimer
- (2012) Christoph Garbers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IL-27 Production and STAT3-Dependent Upregulation of B7-H1 Mediate Immune Regulatory Functions of Liver Plasmacytoid Dendritic Cells
- (2012) B. M. Matta et al. JOURNAL OF IMMUNOLOGY
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Immunomodulatory cytokines as therapeutic agents for melanoma
- (2011) Courtney Nicholas et al. Immunotherapy
- IL-27 renders DC immunosuppressive by induction of B7-H1
- (2011) Svetlana Karakhanova et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Cytokines in Cancer Immunotherapy
- (2011) Sylvia Lee et al. Cancers
- New insights into the mechanisms of hematopoietic cell transformation by activated receptor tyrosine kinases
- (2010) F. Toffalini et al. BLOOD
- Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
- (2010) Eek Joong Park et al. CELL
- Interleukin-27 acts on hepatic stellate cells and induces signal transducer and activator of transcription 1-dependent responses
- (2010) Caroline Schoenherr et al. Cell Communication and Signaling
- IL-35-mediated induction of a potent regulatory T cell population
- (2010) Lauren W Collison et al. NATURE IMMUNOLOGY
- Inflammation and Cancer: IL-6 and STAT3 Complete the Link
- (2009) Jacqueline Bromberg et al. CANCER CELL
- gp130-Mediated Stat3 Activation in Enterocytes Regulates Cell Survival and Cell-Cycle Progression during Colitis-Associated Tumorigenesis
- (2009) Julia Bollrath et al. CANCER CELL
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- Interleukin-27 Activates Natural Killer Cells and Suppresses NK-Resistant Head and Neck Squamous Cell Carcinoma through Inducing Antibody-Dependent Cellular Cytotoxicity
- (2009) M. Matsui et al. CANCER RESEARCH
- Interleukin-27 displays interferon-γ-like functions in human hepatoma cells and hepatocytes
- (2009) Herdis Bender et al. HEPATOLOGY
- Hypoxia-inducible factor 1α is up-regulated by oncostatin M and participates in oncostatin M signaling
- (2009) Stefan Vollmer et al. HEPATOLOGY
- Immunologic and Therapeutic Synergy of IL-27 and IL-2: Enhancement of T Cell Sensitization, Tumor-Specific CTL Reactivity and Complete Regression of Disseminated Neuroblastoma Metastases in the Liver and Bone Marrow
- (2009) R. Salcedo et al. JOURNAL OF IMMUNOLOGY
- The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling
- (2009) S. Crabe et al. JOURNAL OF IMMUNOLOGY
- Interleukin 27: a double-edged sword for offense and defense
- (2009) Hiroki Yoshida et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Expression of interleukins-23 and 27 leads to successful gene therapy of hepatocellular carcinoma
- (2009) Peng Hu et al. MOLECULAR IMMUNOLOGY
- Autocrine IL-6 Signaling: A Key Event in Tumorigenesis?
- (2008) Sergei Grivennikov et al. CANCER CELL
- An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer
- (2008) R. R. Weichselbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IL-27-Mediated Activation of Natural Killer Cells and Inflammation Produced Antitumour Effects for Human Oesophageal Carcinoma Cells
- (2008) L. Liu et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now