A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells

Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

(2014) M. C. B. Tan et al.   JOURNAL OF IMMUNOLOGY

Regulation of the foxp3 Gene by the Th1 Cytokines: The Role of IL-27-Induced STAT1

(2014) N. Ouaked et al.   JOURNAL OF IMMUNOLOGY

Delicate Balance among Three Types of T Cells in Concurrent Regulation of Tumor Immunity

(2013) L. Izhak et al.   CANCER RESEARCH

Critical Role of Dendritic Cell-Derived IL-27 in Antitumor Immunity through Regulating the Recruitment and Activation of NK and NKT Cells

(2013) J. Wei et al.   JOURNAL OF IMMUNOLOGY

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39

(2013) Ivan D Mascanfroni et al.   NATURE IMMUNOLOGY

High susceptibility to liver injury in IL-27 p28 conditional knockout mice involves intrinsic interferon-γ dysregulation of CD4+T cells

(2012) Song Zhang et al.   HEPATOLOGY

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

Targeting Regulatory T Cells in Cancer

(2011) W. L. Byrne et al.   CANCER RESEARCH

A Role for IL-27 in Limiting T Regulatory Cell Populations

(2011) E. D. Tait Wojno et al.   JOURNAL OF IMMUNOLOGY

New directions in the basic and translational biology of interleukin-27

(2011) Elia D. Tait Wojno et al.   TRENDS IN IMMUNOLOGY

Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways

(2010) Roser Gorina et al.   GLIA

NK depletion results in increased CCL22 secretion and Treg levels in Lewis Lung Carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells

(2010) Adam W. Mailloux et al.   INTERNATIONAL JOURNAL OF CANCER

IL-27 promotes T cell–dependent colitis through multiple mechanisms

(2010) Jennifer H. Cox et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A role for IL-27p28 as an antagonist of gp130-mediated signaling

(2010) Jason S Stumhofer et al.   NATURE IMMUNOLOGY

Harnessing the immune response to treat cancer

(2010) H J Steer et al.   ONCOGENE

Clinical Use of Anti-CD25 Antibody Daclizumab to Enhance Immune Responses to Tumor Antigen Vaccination by Targeting Regulatory T cells

(2009) Andrew J. Rech et al.   Annals of the New York Academy of Sciences

Differences in Tumor Regulatory T-Cell Localization and Activation Status Impact Patient Outcome

(2009) C. Menetrier-Caux et al.   CANCER RESEARCH

Regulatory T Cells Recruited through CCL22/CCR4 Are Selectively Activated in Lymphoid Infiltrates Surrounding Primary Breast Tumors and Lead to an Adverse Clinical Outcome

(2009) M. Gobert et al.   CANCER RESEARCH

The IL-27 p28 Subunit Binds Cytokine-Like Factor 1 to Form a Cytokine Regulating NK and T Cell Activities Requiring IL-6R for Signaling

(2009) S. Crabe et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Regulatory T cells and treatment of cancer

(2008) Tyler J Curiel   CURRENT OPINION IN IMMUNOLOGY

Enhanced expression of IL-27 mRNA in human newborns

(2008) Doreen Krumbiegel et al.   PEDIATRIC ALLERGY AND IMMUNOLOGY

Tumor-induced modulation of dendritic cell function

(2007) E GOTTFRIED et al.   CYTOKINE & GROWTH FACTOR REVIEWS