Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages

LRP1 shedding in human brain: roles of ADAM10 and ADAM17

(2009) Qiang Liu et al.   Molecular Neurodegeneration

Ligand Binding to LRP1 Transactivates Trk Receptors by a Src Family Kinase-Dependent Pathway

(2009) Y. Shi et al.   Science Signaling

Regulation of tumor necrosis factor receptor-1 and the IKK-NF- B pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor

(2008) A. Gaultier et al.   BLOOD

The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier Aβ Clearance in Alzheimers Disease

(2008) R. Deane et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular Dissection of the Human α2-Macroglobulin Subunit Reveals Domains with Antagonistic Activities in Cell Signaling

(2008) Elisabetta Mantuano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A shed form of LDL receptor–related protein–1 regulates peripheral nerve injury and neuropathic pain in rodents

(2008) Alban Gaultier et al.   JOURNAL OF CLINICAL INVESTIGATION

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

LDL Receptor-Related Protein 1: Unique Tissue-Specific Functions Revealed by Selective Gene Knockout Studies

(2008) Anna P. Lillis et al.   PHYSIOLOGICAL REVIEWS

 -Secretase Limits the Inflammatory Response Through the Processing of LRP1

(2008) K. Zurhove et al.   Science Signaling