Molecular chaperones and protein-folding catalysts as intercellular signaling regulators in immunity and inflammation

Extracellular HSP90: Conquering the cell surface

(2011) Katerina Sidera et al.   CELL CYCLE

Immunological efficacy of heat shock protein 60 peptide DiaPep277TM therapy in clinical type I diabetes

(2010) V. A. L. Huurman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Mycobacterial 65-kD heat shock protein induces release of proinflammatory cytokines from human monocytic cells

(2010) J. S. FRIEDLAND et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Thioredoxin 1 delivery as new therapeutics

(2009) Hajime Nakamura et al.   ADVANCED DRUG DELIVERY REVIEWS

Thioredoxin Suppresses the Contact Hypersensitivity Response by Inhibiting Leukocyte Recruitment During the Elicitation Phase

(2009) Atsushi Fukunaga et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Cell Survival by the Thioredoxin Superfamily: An Implication of Redox Gene Therapy in the Heart

(2009) Md. Kaimul Ahsan et al.   ANTIOXIDANTS & REDOX SIGNALING

Direct Association of Thioredoxin-1 (TRX) with Macrophage Migration Inhibitory Factor (MIF): Regulatory Role of TRX on MIF Internalization and Signaling

(2009) Aoi Son et al.   ANTIOXIDANTS & REDOX SIGNALING

PAN-DR-Binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis

(2009) Huib de Jong et al.   ARTHRITIS AND RHEUMATISM

Epitope-specific immunotherapy of rheumatoid arthritis: Clinical responsiveness occurs with immune deviation and relies on the expression of a cluster of molecules associated with T cell tolerance in a double-blind, placebo-controlled, pilot phase II trial

(2009) Eva C. Koffeman et al.   ARTHRITIS AND RHEUMATISM

A New Function of GAPDH fromChlamydomonas reinhardtii: A Thiol−Disulfide Exchange Reaction with CP12

(2009) Jenny Erales et al.   BIOCHEMISTRY

Redox-Regulated Chaperones

(2009) Caroline Kumsta et al.   BIOCHEMISTRY

The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions?

(2009) A. Graham Pockley et al.   CELL STRESS & CHAPERONES

Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants

(2009) Brian Henderson et al.   CELL STRESS & CHAPERONES

Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology

(2009) Sergiy Kostenko et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functions and pathologies of BiP and its interaction partners

(2009) J. Dudek et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Strategies for Stalling Malignancy: Targeting Cancers Addiction to Hsp90

(2009) Chrisostomos Prodromou   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Binding of heat shock protein 70 to extracellular phosphatidylserine promotes killing of normoxic and hypoxic tumor cells

(2009) Daniela Schilling et al.   FASEB JOURNAL

Binding immunoglobulin protein-treated peripheral blood monocyte-derived dendritic cells are refractory to maturation and induce regulatory T-cell development

(2009) Valerie M. Corrigall et al.   IMMUNOLOGY

Mycobacterium tuberculosis Cpn60.2 and DnaK Are Located on the Bacterial Surface, Where Cpn60.2 Facilitates Efficient Bacterial Association with Macrophages

(2009) T. B. M. Hickey et al.   INFECTION AND IMMUNITY

Heat shock proteins and immune system

(2009) Min-Fu Tsan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Molecular Chaperone BiP Interacts with Borna Disease Virus Glycoprotein at the Cell Surface

(2009) T. Honda et al.   JOURNAL OF VIROLOGY

Metallothionein as an Anti-Inflammatory Mediator

(2009) Ken-ichiro Inoue et al.   MEDIATORS OF INFLAMMATION

Moonlighting proteins—an update

(2009) Constance J. Jeffery   Molecular BioSystems

Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II–induced aortic aneurysms

(2009) Kimio Satoh et al.   NATURE MEDICINE

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A novel nucleoid-associated protein of Mycobacterium tuberculosis is a sequence homolog of GroEL

(2009) Debashree Basu et al.   NUCLEIC ACIDS RESEARCH

Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells

(2009) P Nirdé et al.   ONCOGENE

The regulatory mechanism of Hsp90α secretion and its function in tumor malignancy

(2009) Xiaofeng Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?

(2009) Yvonne Vercoulen et al.   ARTHRITIS RESEARCH & THERAPY

Endogenous and Exogenous Thioredoxin 1 Prevents Goblet Cell Hyperplasia in a Chronic Antigen Exposure Asthma Model

(2009) Haruki Imaoka et al.   ALLERGOLOGY INTERNATIONAL

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Efficacy and Safety of Chaperonin 10 in Patients With Moderate to Severe Plaque Psoriasis: Evidence of Utility Beyond a Single Indication

(2008) Bronwyn Williams et al.   ARCHIVES OF DERMATOLOGY

Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library

(2008) Jurre Hageman et al.   CELL STRESS & CHAPERONES

Guidelines for the nomenclature of the human heat shock proteins

(2008) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

The two homologous chaperonin 60 proteins ofMycobacterium tuberculosishave distinct effects on monocyte differentiation into osteoclasts

(2008) Vivienne R. Winrow et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosisheat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages

(2008) Nooruddin Khan et al.   CELLULAR MICROBIOLOGY

Extracellular Release of the Atheroprotective Heat Shock Protein 27 Is Mediated by Estrogen and Competitively Inhibits acLDL Binding to Scavenger Receptor-A

(2008) Katey Rayner et al.   CIRCULATION RESEARCH

Serum Heat Shock Protein 27 and Diabetes Complications in the EURODIAB Prospective Complications Study: A Novel Circulating Marker for Diabetic Neuropathy

(2008) G. Gruden et al.   DIABETES

Targeting the chemotactic function of CD147 reduces collagen-induced arthritis

(2008) Jesse M. Damsker et al.   IMMUNOLOGY

A Mycobacterium tuberculosis Mutant Lacking the groEL Homologue cpn60.1 Is Viable but Fails To Induce an Inflammatory Response in Animal Models of Infection

(2008) Y. Hu et al.   INFECTION AND IMMUNITY

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

(2008) Henriette Bendz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioredoxin-1 Ameliorates Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) A. Sato et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Moonlighting Proteins in Yeasts

(2008) C. Gancedo et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Transforming Growth Factor   (TGF )-Stimulated Secretion of HSP90 : Using the Receptor LRP-1/CD91 To Promote Human Skin Cell Migration against a TGF -Rich Environment during Wound Healing

(2008) C.-F. Cheng et al.   MOLECULAR AND CELLULAR BIOLOGY

Results of a phase IIa clinical trial of an anti-inflammatory molecule, chaperonin 10, in multiple sclerosis

(2008) SA Broadley et al.   Multiple Sclerosis Journal

Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3

(2008) Mathias Gehrmann et al.   PLoS One

HSP60 as a Target of Anti-Ergotypic Regulatory T Cells

(2008) Francisco J. Quintana et al.   PLoS One

The dual immunoregulatory roles of stress proteins

(2008) Alan Graham Pockley et al.   TRENDS IN BIOCHEMICAL SCIENCES