期刊
JOURNAL OF LEUKOCYTE BIOLOGY
卷 86, 期 5, 页码 1027-1038出版社
WILEY
DOI: 10.1189/jlb.0309167
关键词
microgravity; deep-space mission; immune depression; stress
资金
- CNES
- ESA
- French Ministry of Higher Education and Research
- Nancy-University
- Lorraine Region
- University of Luxembourg
- National Research Fund of Luxembourg
This year, we celebrate the 40th birthday of the first landing of humans on the moon. By 2020, astronauts should return to the lunar surface and establish an outpost there that will provide a technical basis for future manned missions to Mars. This paper summarizes major constraints associated with a trip to Mars, presents immunological hazards associated with this type of mission, and shows that our current understanding of the immunosuppressive effects of spaceflight is limited. Weakening of the immune system associated with spaceflight is therefore an area that should be considered more thoroughly before we undertake prolonged space voyages. J. Leukoc. Biol. 86: 1027-1038; 2009.
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