期刊
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS
卷 54, 期 13, 页码 809-812出版社
WILEY-BLACKWELL
DOI: 10.1002/jlcr.1936
关键词
deuterium; labeled; synthesis; pregabalin
资金
- Nanjing University of Technology and Nanjing New & High Technology Industry Development Zone
This paper describes the synthesis of deuterium-labeled pregabalin. The stable isotopic-labeled compound was obtained in nine steps starting from the commercially available 4-[2H11]methylvaleric acid as the stable-labeled reagent. It is used as an internal standard for analysis and metabolic studies.
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