Article
Endocrinology & Metabolism
Aziz Sener, Selin Yildiz, Gulce Kiren, Canan Topcuoglu
Summary: New inflammatory markers are useful in assessing albuminuria in T2DM patients, but not in assessing glycemic control.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Endocrinology & Metabolism
Adam H. Dyer, Robert Briggs, Eamon Laird, Leane Hoey, Catherine F. Hughes, Helene McNulty, Mary Ward, J. J. Strain, Anne M. Molloy, Conal Cunningham, Kevin McCarroll
Summary: In older adults, both high HbA(1c) levels and the presence of diabetes are associated with poorer cognitive performance and specific domain-specific neuropsychological performance. This suggests that focusing on HbA(1c) levels, not just diabetes status, may be important for promoting optimal brain health in older adults.
Article
Endocrinology & Metabolism
Olivier G. Polle, Antoine Delfosse, Manon Martin, Jacques Louis, Inge Gies, Marieke den Brinker, Nicole Seret, Marie-Christine Lebrethon, Thierry Mouraux, Laurent Gatto, Philippe A. Lysy
Summary: This study evaluated whether indexes of glycemic variability could overcome residual beta-cell secretion estimates in the longitudinal evaluation of partial remission in pediatric patients with new-onset type 1 diabetes. The combination of CGM metrics and clinical parameters revealed key clinical milestones of glucose homeostasis and remission status during the first year of type 1 diabetes in the pediatric cohort.
Article
Endocrinology & Metabolism
David Simmons
Summary: The diagnosis of gestational diabetes mellitus has traditionally been based on an oral glucose tolerance test at 24-28 weeks of gestation, but with the increasing prevalence of type 2 diabetes in pregnancy, there is a need to identify undiagnosed diabetes as early as possible. Screening for undiagnosed diabetes in early pregnancy can help identify women with higher blood sugar levels but who do not meet the criteria for overt diabetes, leading to a greater risk of adverse pregnancy outcomes.
Article
Endocrinology & Metabolism
Anita Jeyam, Fraser W. Gibb, John A. McKnight, Brian Kennon, Joseph E. O'Reilly, Thomas M. Caparrotta, Andreas Hohn, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Sara Hatam, Rory J. McCrimmon, Graham Leese, Robert S. Lindsay, John Petrie, John Chalmers, Sam Philip, Sarah H. Wild, Naveed Sattar, Paul M. McKeigue, Helen M. Colhoun
Summary: The study aimed to evaluate the use of continuous subcutaneous insulin infusion (CSII) in individuals with type 1 diabetes in Scotland and its impact on glycaemic control. Results showed CSII treatment led to significant reductions in HbA(1c) levels, particularly in those with high baseline levels, and was also associated with lower rates of DKA and SHH events.
Article
Multidisciplinary Sciences
Boonsub Sakboonyarat, Warabhorn Pima, Channarong Chokbumrungsuk, Taksin Pimpak, Sirikorn Khunsri, Supak Ukritchon, Worarachanee Imjaijitt, Mathirut Mungthin, Wisit Kaewput, Bhophkrit Bhopdhornangkul, Nattapol Sathavarodom, Pyatat Tatsanavivat, Ram Rangsin
Summary: Diabetes is a major global health issue with increasing prevalence, and the study in Thailand found that the rate of adequate glycemic control among patients with type 2 diabetes was on the rise. Factors associated with poor glycemic control included gender, age, region, level of care, health insurance scheme, duration of diabetes, body mass index, and presence of hypertension comorbidity.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Anita Jeyam, Fraser W. Gibb, John A. McKnight, Joseph E. O'Reilly, Thomas M. Caparrotta, Andreas Hohn, Stuart J. McGurnaghan, Luke A. K. Blackbourn, Sara Hatam, Brian Kennon, Rory J. McCrimmon, Graham Leese, Sam Philip, Naveed Sattar, Paul M. McKeigue, Helen M. Colhoun
Summary: Results of the study showed that for type 1 diabetes patients using flash monitors, there was a significant reduction in HbA(1c) levels and a noticeable decrease in DKA rates after FM initiation. The use of FM has important implications for improving blood sugar management in diabetic patients.
Article
Geriatrics & Gerontology
Oliver Baretella, Heba Alwan, Martin Feller, Carole E. Aubert, Cinzia Del Giovane, Dimitrios Papazoglou, Antoine Christiaens, Arend-Jan Meinders, Stephen Byrne, Patricia M. Kearney, Denis O'Mahony, Wilma Knol, Benoit Boland, Baris Gencer, Drahomir Aujesky, Nicolas Rodondi
Summary: In multimorbid older patients with type 2 diabetes mellitus (T2DM), more than one third were overtreated, highlighting the high prevalence of this problem. Careful balancing of benefits and risks in the choice of glucose-lowering medication (GLM) may improve patient care, especially in the context of comorbidities such as severe renal impairment, and frequent non-GP healthcare contacts.
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2023)
Article
Endocrinology & Metabolism
Guanhua Chen, Chunlu Tan, Xubao Liu, Yonghua Chen
Summary: The neutrophil-to-lymphocyte ratio (NLR) is significantly higher in patients with diabetes secondary to exocrine pancreatic disorders, and it may serve as a reliable predictive marker for diabetes in this population.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Multidisciplinary Sciences
Tetsuya Akaishi, Tatsuro Misu, Kazuo Fujihara, Naoki Nakaya, Tomohiro Nakamura, Mana Kogure, Rieko Hatanaka, Fumi Itabashi, Ikumi Kanno, Toshiyuki Takahashi, Hiroshi Kuroda, Juichi Fujimori, Yoshiki Takai, Shuhei Nishiyama, Kimihiko Kaneko, Tadashi Ishii, Masashi Aoki, Ichiro Nakashima, Atsushi Hozawa
Summary: Patients with multiple sclerosis showed elevated counts of total white blood cells, monocytes, basophils, and neutrophils at the time of diagnosis. However, the clinical relevance of these biomarkers in the context of the development and progression of MS remains unclear.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Ramkumar V. Venkateswaran, M. V. Moorthy, Neal A. Chatterjee, Julie Pester, Alan H. Kadish, Daniel C. Lee, Nancy R. Cook, Christine M. Albert
Summary: In patients with coronary artery disease and left ventricular ejection fraction of >30% to 35%, those with diabetes mellitus and/or elevated HbA1c are at a much higher absolute risk of non-sudden/arrhythmic death compared to sudden/arrhythmic death. Clinical risk markers, rather than HbA1c, are associated with sudden/arrhythmic death risk in patients with diabetes mellitus.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Endocrinology & Metabolism
Jing Zeng, Min Chen, Qiu Feng, Haiyan Wan, Jianbo Wang, Fan Yang, Hongyi Cao
Summary: Diabetic retinopathy (DR) is a severe neurovascular complication of type 2 diabetes mellitus (T2DM) and chronic inflammation potentially plays a significant role in its pathogenesis. This study found that platelet-to-lymphocyte ratio (PLR) may be an independent risk factor for evaluating DR in T2DM patients.
DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY
(2022)
Article
Endocrinology & Metabolism
Peng Ning, Fan Yang, Jun Kang, Jing Yang, Jiaxing Zhang, Yi Tang, Yanghong Ou, Haiyan Wan, Hongyi Cao
Summary: This study found that platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR) were associated with arterial stiffness in patients with diabetes. Among them, NLR showed higher accuracy in predicting arterial stiffness.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Medicine, General & Internal
Murat Sahin, Ayten Oguz, Dilek Tuzun, Okay Isiktas, Songul Isiktas, Cansu ulgen, Hatice Sahin, Kamile Gul
Summary: This study aimed to investigate whether the neutrophil-lymphocyte ratio (NLR), an indicator of systemic inflammation, could predict gestational diabetes mellitus (GDM). The results showed a significant increase in NLR in the 1st and 3rd trimesters in the GDM group, supporting the presence of systemic inflammation in early pregnancy and throughout pregnancy. The study also found a positive correlation between NLR and fasting plasma glucose and body mass index in both trimesters. The first trimester NLR was found to independently predict the development of GDM.
Article
Oncology
Suping Ling, Michael Sweeting, Francesco Zaccardi, David Adlam, Umesh T. Kadam
Summary: This study assessed the association between glycemic control and prognosis in cancer patients with pre-existing diabetes. Fifteen eligible observational studies involving 10,536 patients reported that poor glycemic control was associated with increased risks of all-cause mortality, cancer-specific mortality, and cancer recurrence. Dose-response analyses also showed that each 1-unit increase in HbA(1c) was associated with increased risks of mortality. These findings highlight the importance of maintaining optimal glycemic control in cancer patients with diabetes.
Meeting Abstract
Oncology
Onal Cem, Ali Murat Sedef, Fatih Kose, Ezgi Oymak, Ozan Cem Guler, Ahmet Taner Sumbul, Sercan Aksoy, Berna Akkus Yildrim, Ali Ayberk Besen, Sadik Mullaoglu, Huseyin Mertsoylu, Gokhan Ozyigit
JOURNAL OF CLINICAL ONCOLOGY
(2019)
Article
Horticulture
Erdal Aglar, Ahmet Sumbul, Orhan Karakaya, Burhan Ozturk
ACTA SCIENTIARUM POLONORUM-HORTORUM CULTUS
(2020)
Article
Medicine, Research & Experimental
Feridun Bulbul, Irfan Koca, Esen Savas, Recep Dokuyucu
MEDICAL SCIENCE MONITOR
(2020)
Article
Medicine, General & Internal
Irfan Koca, Recep Dokuyucu, Zeynel Abidin Tas, Hasan Gokce, Oguzhan Ozcan
IRANIAN RED CRESCENT MEDICAL JOURNAL
(2020)
Article
Biochemistry & Molecular Biology
Beyhan Cengiz, Mehmet Bostanciklioglu, Tuncer Demir, Hayriye Karabulut, Recep Dokuyucu, Mustafa Ulasli
CURRENT MOLECULAR PHARMACOLOGY
(2020)
Article
Urology & Nephrology
Deniz Tural, Omer Fatih Olmez, Ahmet Taner Sumbul, Mehmet Artac, Nail Ozhan, Emre Akar, Burcu Cakar, Osman Kostek, Meltem Ekenel, Mustafa Erman, Hasan Senol Coskun, Fatih Selcukbiricik, Ozge Keskin, Fatma Paksoy Turkoz, Kerem Oruc, Selami Bayram, Ugur Yglmaz, Irem Bilgetekin, Birol Ygldgz, Mehmet Ali Nahit Sendur, Nail Paksoy, Ahmet Dirican, Dilek Erdem, Meltem Selam, Ozgur Tanrgverdi, Semra Paydas, Zuhat Urakcg, Elif Atag, Sabri Guncan, Yuksel Urun, Ali Alkan, Ali Osman Kaya, Deniz Tataroglu Ozyukseler, Halil Taskaynatan, Mustafa Ygldgrgm, Muge Sonmez, Tugba Basoglu, Seyda Gunduz, Saadettin Kglgckap
Summary: This study analyzed data from 115 patients with metastatic bladder cancer treated with atezolizumab, finding it to be effective and well tolerated in patients who had progressed with previous treatment. Despite some limitations, the results are consistent with previous clinical trial outcomes.
EUROPEAN UROLOGY FOCUS
(2021)
Article
Agronomy
Ercan Yildiz, Hasan Pinar, Aydin Uzun, Mehmet Yaman, Ahmet Sumbul, Sezai Ercisli
Summary: The study revealed high genetic diversity in walnuts, primarily driven by the kernel ratio. Molecular analysis showed a significant amount of polymorphism in the SRAP primer combinations, indicating high genetic diversity in walnuts. Additionally, walnut kernel oils consist mainly of linoleic acid, with polyunsaturated fatty acids being the predominant fatty acid group.
GENETIC RESOURCES AND CROP EVOLUTION
(2021)
Article
Medicine, General & Internal
Veli Yildirim, Seref Simsek, Ihsan Cetin, Recep Dokuyucu
Summary: In this study, we found that children with ASD had higher levels of KP products and interleukin-6 in their serum, which may be related to the pathogenesis and inflammatory processes of ASD. However, these biomarkers were not significantly associated with the severity of ASD.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
M. B. Dal, K. T. Ulutas
Summary: The study found that in acute pancreatitis, subcutaneous fat significantly increased while visceral fat decreased. The roles of visceral and subcutaneous fat in AP and their impact on fat necrosis should be studied in different research paths.
NIGERIAN JOURNAL OF CLINICAL PRACTICE
(2021)
Article
Oncology
Ahmet Sezer, Berna Akkus, Ozan Cem Guler, Huseyin Cem Onal, Ahmet Taner Sumbul
Article
Medicine, General & Internal
Kemal Turker Ulutas, Mehmet Burak Dal
CUKUROVA MEDICAL JOURNAL
(2019)
Article
Medicine, General & Internal
Mehmet Emin Celikkaya, Bulent Akcora, Sibel Hakverdi, Burcin Ozer, Kemal Turker Ulutas, Nizami Duran
EURASIAN JOURNAL OF MEDICINE
(2019)
Article
Oncology
Ali Murat Sedef, Fatih Kose, Ahmet Taner Sumbul, Ali Ayberk Besen, Bekir Hacioglu, Meral Gunaldi, Erdinc Nayir, Ozgur Tanriverdi, Erkan Arpaci, Huseyin Abali, Ozgur Ozyilkan
Article
Oncology
Ali Murat Sedef, Zuleyha Calikusu, Aykut Bahceci, Serkan Gokcay, Ahmet Taner Sumbul
TURK ONKOLOJI DERGISI-TURKISH JOURNAL OF ONCOLOGY
(2019)
