期刊
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
卷 41, 期 4, 页码 1088-1097出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0300060513487645
关键词
Liver abscess; hypermucoviscosity; Klebsiella pneumoniae; magA; rmpA; aerobactin
资金
- Capital Health Research and Development of Special Capital fund [2011-2008-07]
Objective: To perform a retrospective comparison of the clinical and radiological features of Klebsiella pneumoniae (KP)-associated and non-KP-associated pyogenic liver abscesses (PLA) in Chinese patients. Methods: Patients with confirmed diagnoses of bacterial liver abscess at three Beijing hospitals were enrolled. Clinical isolates from liver abscesses were used to determine serology and expression of hypermucoviscosity genes. Basic clinical, ultrasonographic (US) and computed tomography (CT) data were recorded and compared between patients with KP- and non-KP-associated PLA. Results: A total of 101 (77.10%) and 30 (22.90%) cases were due to KP and non-KP pathogens, respectively. Compared with the non-KP cohort, the KP cohort demonstrated a significantly higher incidence of underlying diabetes mellitus, and more gas-forming abscesses, as demonstrated by US and CT examinations. Prior abdominal surgery or chemoradiation therapy was significantly associated with non-KP cases. The non-KP group had a higher chance of a clear edge, compared with the KP group, on pre-contrast CT images. Conclusion: KP and non-KP-associated PLA have distinctive risk factors and unique US and CT features, in Chinese patients.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据