A BMD threshold for treatment efficacy in osteoporosis? A need to consider the whole evidence base

The real enemy is fragility fracture, not osteoporosis

(2015) C. E. Uzoigwe   OSTEOPOROSIS INTERNATIONAL

Overdiagnosis of bone fragility in the quest to prevent hip fracture

(2015) T. L. Jarvinen et al.   BMJ-British Medical Journal

Overdiagnosis of bone fragility in the quest to prevent hip fracture

(2015) T. L. Jarvinen et al.   BMJ-British Medical Journal

Assessing the Impact of Osteoporosis on the Burden of Hip Fractures

(2012) Anders Odén et al.   CALCIFIED TISSUE INTERNATIONAL

Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX

(2012) Eugene V McCloskey et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effect of denosumab treatment on the risk of fractures in subgroups of women with postmenopausal osteoporosis

(2011) Michael R McClung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

High fracture probability with FRAX® usually indicates densitometric osteoporosis: implications for clinical practice

(2011) W. D. Leslie et al.   OSTEOPOROSIS INTERNATIONAL

Fracture risk assessment without bone density measurement in routine clinical practice

(2011) W. D. Leslie et al.   OSTEOPOROSIS INTERNATIONAL

Efficacy and Safety of a Once-Yearly Intravenous Zoledronic Acid 5 mg for Fracture Prevention in Elderly Postmenopausal Women with Osteoporosis Aged 75 and Older

(2010) Steven Boonen et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Bazedoxifene reduces vertebral and clinical fractures in postmenopausal women at high risk assessed with FRAX®

(2009) John A. Kanis et al.   BONE

Effect of Once-Yearly Zoledronic Acid Five Milligrams on Fracture Risk and Change in Femoral Neck Bone Mineral Density

(2009) Richard Eastell et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

BMD, clinical risk factors and their combination for hip fracture prevention

(2009) H. Johansson et al.   OSTEOPOROSIS INTERNATIONAL

Ten-year fracture probability identifies women who will benefit from clodronate therapy—additional results from a double-blind, placebo-controlled randomised study

(2008) E. V. McCloskey et al.   OSTEOPOROSIS INTERNATIONAL