期刊
OSTEOARTHRITIS AND CARTILAGE
卷 23, 期 5, 页码 698-715出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.joca.2015.03.012
关键词
Knee osteoarthritis; Imaging; Clinical trial recommendations
资金
- NHMRC Health Practitioner Fellowship
- NIH [AR062068, EB002524]
Significant advances have occurred in our understanding of the pathogenesis of knee osteoarthritis (OA) and some recent trials have demonstrated the potential for modification of the disease course. The purpose of this expert opinion, consensus driven exercise is to provide detail on how one might use and apply knee imaging in knee OA trials. It includes information on acquisition methods/techniques (including guidance on positioning for radiography, sequence/protocol recommendations/hardware for magnetic resonance imaging (MRI)); commonly encountered problems (including positioning, hardware and coil failures, sequences artifacts); quality assurance (QA)/control procedures; measurement methods; measurement performance (reliability, responsiveness, validity); recommendations for trials; and research recommendations. (C) 2015 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
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