Article
Optics
Shiqi Jia, Jie Peng, Yuqiong Cheng, Shubo Wang
Summary: This study proposes a method to detect small chiral particles using the C lines in light scattering by a metal sphere. Using numerical simulations and analytical methods, the authors find that the absorption dissymmetry can be much larger than that induced by circularly polarized plane-wave excitation. The results also show that the absorption dissymmetry strongly depends on the anisotropy of the helices.
Article
Physics, Multidisciplinary
Q. H. Ye, X. D. Chen, S. Wang, Z. Y. Hu, G. Song
Summary: We theoretically investigated a method to distinguish the chirality of molecules directly through reflection spectra, utilizing a metal film sandwiched between reference and tested molecules. By adjusting the oscillator strength of the reference molecules, we found an optimal regime for distinguishing left and right-handed TDBCs at the end of the tested molecules.
Article
Chemistry, Multidisciplinary
Sofia O. Parreiras, Daniel Moreno, Shanmugasibi K. Mathialagan, Beatriz Muniz-Cano, Cristina Martin-Fuentes, Maria Tenorio, Lenka Cerna, Jose I. Urgel, Koen Lauwaet, Manuel Valvidares, Miguel A. Valbuena, Jose M. Gallego, Jose I. Martinez, Pierluigi Gargiani, Rodolfo Miranda, Julio Camarero, David Ecija
Summary: The coordination of lanthanides atoms in two-dimensional surface-confined metal-organic networks is a promising path to achieve an ordered array of single atom magnets. Here we introduce an Er-directed two-dimensional metallosupramolecular network on Cu(111) featuring strong out-of-plane magnetic anisotropy. Our results will contribute to pave avenues for the use of lanthanides in potential applications in nanomagnetism and spintronics.
Article
Optics
C. N. Alexeyev, E. Barshak, B. P. Lapin, M. A. Yavorsky
Summary: This Letter discusses the impact of losses and gains on the generation of optical vortices in a chiral fiber, showing that losses can play a constructive role. The study of field evolution at the exceptional point reveals the formation of a special attractor mode with average OAM at the generalized Poincare sphere. This attractor mode is represented by the OAM black hole, analogous to the spin black hole introduced in a previous study.
Article
Materials Science, Multidisciplinary
Zhehong Liu, Xiao Wang, Xubin Ye, Xudong Shen, Yuecheng Bian, Wei Ding, Stefano Agrestini, Sheng-Chieh Liao, Hong-Ji Lin, Chien-Te Chen, Shih-Chang Weng, Kai Chen, Philippe Ohresser, Lucie Nataf, Francois Baudelet, Zhigao Sheng, Sonia Francoual, Jose R. L. Mardegan, Olaf Leupold, Zefang Li, Xuekui Xi, Wenhong Wang, Liu Hao Tjeng, Zhiwei Hu, Youwen Long
Summary: A quadruple perovskite oxide CaCu3Co2Re2O12 was synthesized by high-pressure annealing, showing unique A- and B-site ordered quadruple perovskite structure. It exhibits long-range antiferromagnetic and ferrimagnetic phase transitions, with strong electrical insulating behavior and an energy gap of approximately 3.75 eV. Spin interactions mechanisms are discussed in detail.
Article
Chemistry, Multidisciplinary
Jessica Wade, Jochen R. Brandt, David Reger, Francesco Zinna, Konstantin Y. Amsharov, Norbert Jux, David L. Andrews, Matthew J. Fuchter
Summary: The study presents a method to achieve nearly 1000-fold chiroptical amplification by embedding a pi-extended superhelicene in an achiral conjugated polymer matrix. This approach significantly increases the chiroptical factor of the superhelicene in solid-state blend films, offering a simple and versatile way to enhance the g-factors of small organic molecules.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Materials Science, Multidisciplinary
Aram Kostanyan, Christin Schlesier, Rasmus Westerstrom, Jan Dreiser, Fabian Fritz, Bernd Buechner, Alexey A. Popov, Cinthia Piamonteze, Thomas Greber
Summary: Endohedral fullerenes are ideal nanolaboratories for studying magnetism. The replacement of a diamagnetic scandium atom with gadolinium in Dy2ScN@C-80 accelerates thermal equilibrium and shows Gd to act as a single atom catalyst. Observations from magnetic methods and X-ray magnetic circular dichroism reveal the effects of Gd on the ground state, as well as the importance of angular momentum balance and symmetry in magnetic relaxation.
Article
Chemistry, Multidisciplinary
Liangliang Gu, Rong Shu, Xiangfeng Liu, Haifeng Hu, Qiwen Zhan
Summary: In this work, a diffractive circular dichroism enhancement technique using stereoscopic plasmonic molecule structures is proposed. The dominant chiral scattering mechanism is identified as the z-component of the electric dipole during the interaction between an individual plasmonic molecule and a grazing plane wave. Through the design of periodic plasmonic molecule structures, large diffractive circular dichroism can be achieved, which is validated by numerical simulations and experimental results. The proposed approach has potential application in enhanced spectroscopy techniques for measuring chiral information, crucial for fundamental physical and chemical research as well as bio-sensing applications.
Article
Biochemistry & Molecular Biology
Mohd Shahnawaz Khan, Md Tabish Rehman, Gouse M. Shaik, Abdulaziz Mohammed Alamri, Mohamed F. AlAjmi, Mohammed Arshad, Majed S. Alokail
Summary: This study investigates the impact of azorubine, a common food and drink colorant, on protein structures using human serum albumin (HSA) as a model protein. The results show that azorubine destabilizes the conformation of HSA and induces the formation of aggregates, especially at acidic conditions. The study also reveals the concentration-dependent toxicity of albumin aggregates.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Samuel R. Clowes, Dora M. Rasadean, Tiberiu-M. Gianga, Tamas Javorfi, Rohanah Hussain, Giuliano Siligardi, G. Dan Pantos
Summary: Cyanine dyes can form H- and J-aggregates in water. We discovered that the cyanine dye S0271 can assemble into vortex-induced chiral J-aggregates in water. The chirality of the J-aggregates is determined by the directionality of the vortex. This study used conventional benchtop CD spectropolarimeters and Mueller matrix polarimetry to analyze the aggregates.
Article
Physics, Multidisciplinary
D. Facciala, M. Devetta, S. Beauvarlet, N. Besley, F. Calegari, C. Callegari, D. Catone, E. Cinquanta, A. G. Ciriolo, L. Colaizzi, M. Coreno, G. Crippa, G. De Ninno, M. Di Fraia, M. Galli, G. A. Garcia, Y. Mairesse, M. Negro, O. Plekan, P. Prasannan Geetha, K. C. Prince, A. Pusala, S. Stagira, S. Turchini, K. Ueda, D. You, N. Zema, V. Blanchet, L. Nahon, I. Powis, C. Vozzi
Summary: Chirality is important in nature and its observation in chiral molecules is crucial for understanding and controlling chiral activity. The technique of time-resolved photoelectron circular dichroism (TR-PECD) offers a powerful tool for studying photoexcited chiral systems. However, the nonlocal nature of the PECD effect makes the interpretation of TR-PECD experiments challenging.
Correction
Optics
P. Roth, Y. Chen, M. C. Gunendi, R. Beravat, N. N. Edavalath, M. H. Frosz, G. Ahmed, G. K. L. Wong, P. St. J. Russell
Summary: Recent work has identified an error in the dispersion relation of helical Bloch modes in a ring of capillaries. The error has been corrected, and a revised version of Fig. 2 is provided.
Article
Chemistry, Multidisciplinary
Jiaqi Guo, Fan Wu, Gang Song, Yuming Huang, Rongzhen Jiao, Li Yu
Summary: The study experimentally measured the spectra of plexcitonic hybrids and investigated the chirality of J-aggregates assembled on the surface of nanoparticles, revealing that the chirality of J-aggregates is related to the position on the nanorods and the quantity of dye molecules. The interaction between the longitudinal localized surface plasmon resonance (LLSPR) of the nanorods and J-aggregates achieved the strong coupling regime, leading to Rabi splitting observation.
Article
Chemistry, Multidisciplinary
Markus Ilchen, Philipp Schmidt, Nikolay M. Novikovskiy, Gregor Hartmann, Patrick Rupprecht, Ryan N. Coffee, Arno Ehresmann, Andreas Galler, Nick Hartmann, Wolfram Helml, Zhirong Huang, Ludger Inhester, Alberto A. Lutman, James P. MacArthur, Timothy Maxwell, Michael Meyer, Valerija Music, Heinz-Dieter Nuhn, Timur Osipov, Dipanwita Ray, Thomas J. A. Wolf, Sadia Bari, Peter Walter, Zheng Li, Stefan Moeller, Andre Knie, Philipp V. Demekhin
Summary: This experiment demonstrates how two-color X-ray pump X-ray probe experiments with polarization control enable XFELs as tools for chiral recognition. By using a linearly polarized X-ray photon to trigger the photolysis of a prototypical chiral molecule and probe the evolving structure with a time-delayed second X-ray pulse, the researchers were able to investigate the stereochemical sensitivity of the inner-shell electrons of the ionic mother-fragment.
COMMUNICATIONS CHEMISTRY
(2021)
Article
Optics
Sony Udayan, Drishya Elizebath, D. R. Sherin, Vakayil K. Praveen, Sini Sunny, Purushothaman Jayamurthy, T. K. Manojkumar, V. P. N. Nampoori, Sheenu Thomas
Summary: This study demonstrates the use of a hexamethine hemicyanine dye as a thermo-optical probe for serum albumin, revealing significant alterations in optical and thermal properties upon binding with the protein. Spectroscopic techniques and molecular docking methods were utilized to investigate the interaction between the dye and serum albumin, indicating enhanced stability of proteins and reduced thermal diffusivity of the dye when bound with the albumin.
OPTICS AND LASER TECHNOLOGY
(2021)
Article
Chemistry, Physical
Elia Grueso, Rosa M. Giraldez-Perez, Edyta Kuliszewska, Jesus A. Guerrero, Rafael Prado-Gotor
Summary: A new method for detecting DNA and lysozyme biomolecules was developed using gold nanoparticles, with a practical and economical approach. The method showed high sensitivity and immediate results, avoiding issues with time delays seen in previous sensor designs.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Pharmacology & Pharmacy
Rosa M. Giraldez-Perez, Elia Grueso, Inmaculada Dominguez, Nuria Pastor, Edyta Kuliszewska, Rafael Prado-Gotor, Francisco Requena-Domenech
Summary: The design and preparation of novel nanocarriers for transporting cancer drugs is crucial in chemotherapy research. By utilizing two new biocompatible gold nanosystems, a new 5-Fluorouracil (5-Fu) transporter was developed, enhancing efficacy, biocompatibility, and selectivity against lung cancer cells. Various techniques were used to study the physicochemical properties and uptake of the nanosystems, demonstrating the potential for improved cancer treatment strategies.
Article
Chemistry, Multidisciplinary
Axel Gomes, Jose M. Carnerero, Aila Jimenez-Ruiz, Elia Grueso, Rosa M. Giraldez-Perez, Rafael Prado-Gotor
Summary: This study investigated the adsorption of lysozyme onto gold nanoparticles and obtained the free energy of binding of the system for the first time. The interactions between lysozyme and AuNPs induce aggregation of citrate-stabilized AuNPs at low concentrations. The study also found that 10 nm AuNPs were the most appropriate for this interaction.
Article
Chemistry, Analytical
Domingo Gonzalez-Arjona, Emilio Roldan Gonzalez, German Lopez-Perez, Manuel Maria Dominguez Perez, Marina Calero-Castillo
Summary: In this study, a coulometer was developed using a digitally controlled galvanostat. A simple colorimeter based on a RGB LED was used as a light emitter, coupled with light dependent resistance and photodiodes as endpoint detectors. Both hardware and software were adapted to optimize the system. The system was tested with different titration processes and achieved reproducibility results below 1%.
Article
Pharmacology & Pharmacy
Rosa M. Giraldez-Perez, Elia M. Grueso, Raquel Jimenez-Aguayo, Alfonso Carbonero, Marina Gonzalez-Bravo, Edyta Kuliszewska, Rafael Prado-Gotor
Summary: This study prepared new nanosystems for effective antibiotic delivery, exhibiting good antibacterial properties and internalization capacity in bacteria, making them suitable for medical applications.
Article
Biochemistry & Molecular Biology
Rosa M. Giraldez-Perez, Elia Grueso, Antonio J. Montero-Hidalgo, Raul M. Luque, Jose M. Carnerero, Edyta Kuliszewska, Rafael Prado-Gotor
Summary: In this study, different gold nanosystems were designed and synthesized for cancer therapy. It was found that gold nanoparticles can induce compaction of DNA-Doxo, enabling efficient drug delivery with high selectivity towards cancer cells. In vitro experiments showed that these compacted nanocomplexes exhibit strong therapeutic effects in cancer cell lines, while protecting non-tumor cell lines.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Analytical
Cristina Roman-Hidalgo, German Lopez-Perez, Mercedes Villar-Navarro, Maria Jesus Martin-Valero
Summary: A simple, rapid, and environmentally friendly method for the electromembrane extraction of polyphenolic compounds using chitosan films as biopolymeric membrane has been developed. The use of organic solvents has been completely eliminated, resulting in high enrichment factors, wide concentration ranges, good linearity, low detection limits, and repeatability.
Editorial Material
Chemistry, Multidisciplinary
Rafael Prado-Gotor
Review
Chemistry, Analytical
Cristina Roman-Hidalgo, Luisa Barreiros, Mercedes Villar-Navarro, German Lopez-Perez, Maria Jesus Martin-Valero, Marcela A. Segundo
Summary: Green and environmentally friendly approaches are necessary for developing newanalytical methodologies. Electromembrane extraction (EME) has offered new alternatives to traditional plastic materials, particularly those derived from bio-polymers, which are biodegradable and sustainable. This review focuses on recent advances in EME procedures using sustainable biopolymer-based materials, discussing their properties, synthesis, and analytical application. By improving analytical methodologies for sample processing and contributing to sustainability, EME methods contribute to the green and environmentally friendly development.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Elia Grueso, Rosa M. Giraldez-Perez, Rafael Prado-Gotor, Edyta Kuliszewska
Summary: Surfactant-capped gold nanoparticles were used to develop a colorimetric sensor based on plasmonic shift through the disaggregation mechanism. The sensor showed an instantaneous color change from blue to red with increasing biopolymer concentrations. The detection limit for DNA and Lysozyme sensing was in the nanomolar and picomolar range, respectively, and the sensor's response was immediate and highly dependent on the order of addition of reagents.
Article
Biochemistry & Molecular Biology
Cristina Roman-Hidalgo, Maria Jesus Martin-Valero, German Lopez-Perez, Mercedes Villar-Navarro
Summary: A chitosan biopolymeric membrane was used as a support for the simultaneous extraction of parabens and fluoroquinolones in the presence of non-steroidal anti-inflammatory drugs. The optimized conditions provided high enrichment factors and good analytical performance. The method was successfully applied to different water samples. The use of chitosan membrane offers advantages as a biodegradable and versatile support.
Article
Chemistry, Analytical
German Lopez-Perez, Domingo Gonzalez-Arjona, Emilio Roldan Gonzalez, Cristina Roman-Hidalgo
Summary: There is a growing need for portable, highly sensitive measuring equipment for in situ and real-time sample analysis. A flexible and low-cost fluorimeter has been developed based on a C12880 MA MEMS micro-spectrometer and an Arduino compatible breakout board. The device offers high sensitivity and low quantitation limits, with the ability to use different excitation sources for investigating various fluorophore compounds. It is also capable of quantifying chloride anions in aqueous solutions with a LOD value of 18 ppm.
Article
Biochemistry & Molecular Biology
Michael Ramek, Jasmina Sabolovic
Summary: This paper investigates the geometries, energy landscapes, and magnetic parameters of copper(II) amino acid compounds using density functional theory calculations. The results show that certain conformers with histaminate-like and glycine-like modes have low Gibbs free energies and high metal-binding affinities. The predicted conformations reproduce the experimental electron paramagnetic resonance parameters.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Wei Tian, Wen Zhong, Zengyan Yang, Ling Chen, Shijie Lin, Yanping Li, Yuxing Wang, Peilin Yang, Xing Long
Summary: A series of novel dibutyltin complexes based on salen-like ligands were synthesized and characterized. Complex S03 showed excellent in vitro anticancer activity and induced cancer cell death through multiple mechanisms. This study reveals new mechanisms of organotin complexes and provides new insights into the development of organotin metal complexes as anticancer drugs.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Natalie C. Korkola, Martin J. Stillman
Summary: Many proteins require a metal cofactor for their function, and these metals play a role in protein folding. The study found that the metallation rates of different metal binding pathways are influenced by pH, with the less cooperative pathway being more affected by low pH conditions. Specific mixtures of structures are formed in the initial steps of metallation, and unfolding the disordered apo-MT structure hinders the formation of these preliminary structures. The compact conformation of the native apo-MT allows for rapid formation of metal-thiolate structures with high affinity, providing protection from oxidation.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Boxuan Yang, Xitong Song, Binju Wang
Summary: The diiron active site plays a crucial role in catalytic transformations in both biological and chemical systems. Recent advancements in the field include the synthesis of biomimetic diiron catalysts inspired by the active structure of soluble methane monooxygenase (sMMO), which have been successfully applied to the dehydrogenation of indolines.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Christina N. Banti, Angeliki A. Piperoudi, Catherine P. Raptopoulou, Vassilis Psycharis, Constantinos M. Athanassopoulos, Sotiris K. Hadjikakou
Summary: Two copper(I) polymorphs with mitochondria-targeting properties were successfully prepared via metal ion conjugation. These compounds showed promising activities in DNA binding, enzyme inhibition, and cancer cell inhibition. The molecular mechanisms of action were investigated.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2024)
