期刊
JOURNAL OF INORGANIC BIOCHEMISTRY
卷 102, 期 5-6, 页码 1359-1365出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jinorgbio.2008.01.027
关键词
IOP1; nar1; iron-sulfur protein; Arabidopsis thaliana
The knockdown of a [FeFe]-hydrogenase-like gene in the model plants Medicago truncatula and Arabidopsis thaliana resulted in a mutant with a dwarf phenotype. Surprisingly, the phenotype is undistinguishable from wild type under hypoxic conditions. The heterologous expression of the plant gene in Escherichia coli indicates that the resulting protein probably coordinates two [Fe-S] clusters with different magnetic properties. Sequence alignment analysis indicates that these two clusters would be topologically equivalent to the mesial and proximal [Fe-S] centers of [FeFe]-hydrogenases. A possible role of the gene product in oxygen signaling pathways is discussed. (C) 2008 Elsevier Inc. All rights reserved.
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