期刊
JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS
卷 20, 期 3, 页码 554-563出版社
SPRINGER
DOI: 10.1007/s10904-010-9379-0
关键词
Antimicrobial polymers; Biocidal polymers; Grafted polysiloxane; Chain transfer polymerization; Organosiloxane copolymers; t-Butylamine
资金
- Medical University of Gdansk
- Center of Molecular and Macromolecular Studies of the Polish Academy of Sciences
- [N205 129935]
- [N205 012834]
Two kinds of new biocidal siloxane copolymers were synthesized, poly-[3(t-butylamino)propyl]methylsiloxane-co-(3-chloropropyl)methylsiloxane] and poly[dimethylsiloxane-co-(3-mercaptopropyl)methylsiloxane]-g-poly-2(t-butylamino)ethyl methacrylate]. Water-soluble derivatives of these copolymers, having charged ammonium groups, were also obtained. The copolymers were tested against two Gram-positive and three Gram-negative bacterial strains. The antibacterial tests for the water-soluble copolymers with charged ammonium groups were performed in aqueous solutions. Both these copolymers were active against the Gram-positive bacterial strains and inactive or moderately active against Gram-negative bacteria. The uncharged, insoluble, t-butylamine substituted copolymers were tested using a two-phase water-copolymer system. In this test both copolymers having the uncharged t-butylamine functions showed a high biocidal potency against the bacteria studied including those Gram-negative ones.
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