S100A8 and S100A9: New Insights into Their Roles in Malignancy

S100A8 enhances osteoclastic bone resorption in vitro through activation of Toll-like receptor 4: Implications for bone destruction in murine antigen-induced arthritis

(2011) Lilyanne C. Grevers et al.   ARTHRITIS AND RHEUMATISM

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

S100A8/A9 Activate Key Genes and Pathways in Colon Tumor Progression

(2011) M. Ichikawa et al.   MOLECULAR CANCER RESEARCH

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

(2010) Suzanne Ostrand-Rosenberg   CANCER IMMUNOLOGY IMMUNOTHERAPY

Gr-1+CD11b+ Myeloid Cells Tip the Balance of Immune Protection to Tumor Promotion in the Premetastatic Lung

(2010) H. H. Yan et al.   CANCER RESEARCH

Smad4 loss is associated with fewer S100A8-positive monocytes in colorectal tumors and attenuated response to S100A8 in colorectal and pancreatic cancer cells

(2010) Chin Wee Ang et al.   CARCINOGENESIS

Lack of an Endogenous Anti-inflammatory Protein in Mice Enhances Colonization of B16F10 Melanoma Cells in the Lungs

(2010) Arjun Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Toll-like receptor 4 ligands Mrp8 and Mrp14 are crucial in the development of autoreactive CD8+ T cells

(2010) Karin Loser et al.   NATURE MEDICINE

S100A8/A9: A Janus-faced molecule in cancer therapy and tumorgenesis

(2009) Saeid Ghavami et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis

(2009) Julia Németh et al.   HEPATOLOGY

Cellular and molecular pathways linking inflammation and cancer

(2009) Chiara Porta et al.   IMMUNOBIOLOGY

Distinct populations of metastases-enabling myeloid cells expand in the liver of mice harboring invasive and preinvasive intra-abdominal tumor

(2009) Michael K. Connolly et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The endogenous Toll-like receptor 4 agonist S100A8/S100A9 (calprotectin) as innate amplifier of infection, autoimmunity, and cancer

(2009) Jan M. Ehrchen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Receptor for AGE (RAGE) and its ligands—cast into leading roles in diabetes and the inflammatory response

(2009) Shi Fang Yan et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer

(2009) Hye-Jung Kim et al.   JOURNAL OF PROTEOME RESEARCH

Mechanisms of regulated unconventional protein secretion

(2009) Walter Nickel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Myeloid-derived suppressor cell role in tumor-related inflammation

(2008) Luigi Dolcetti et al.   CANCER LETTERS

Tumors Sound the Alarmin(s)

(2008) S. B. Coffelt et al.   CANCER RESEARCH

Apoptosis and non-apoptotic deaths in cancer development and treatment response

(2008) Elza C. de Bruin et al.   CANCER TREATMENT REVIEWS

RAGE, carboxylated glycans and S100A8/A9 play essential roles in colitis-associated carcinogenesis

(2008) Olga Turovskaya et al.   CARCINOGENESIS

Migratory neighbors and distant invaders: tumor-associated niche cells

(2008) J. Wels et al.   GENES & DEVELOPMENT

RAGE signaling sustains inflammation and promotes tumor development

(2008) Christoffer Gebhardt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

S100A8/A9 at low concentration promotes tumor cell growth via RAGE ligation and MAP kinase-dependent pathway

(2008) S. Ghavami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Global Gene Expression Profiling Unveils S100A8/A9 as Candidate Markers in H-Ras-Mediated Human Breast Epithelial Cell Invasion

(2008) A. Moon et al.   MOLECULAR CANCER RESEARCH

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY

Myeloid-related proteins S100A8/S100A9 regulate joint inflammation and cartilage destruction during antigen-induced arthritis

(2007) P L E M van Lent et al.   ANNALS OF THE RHEUMATIC DISEASES