Mucopolysaccharide diseases: A complex interplay between neuroinflammation, microglial activation and adaptive immunity

Characterisation of the T cell and dendritic cell repertoire in a murine model of mucopolysaccharidosis I (MPS I)

(2012) Louise D Archer et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Neuropathology in Mouse Models of Mucopolysaccharidosis Type I, IIIA and IIIB

(2012) Fiona L. Wilkinson et al.   PLoS One

Hyperactive behaviour in the mouse model of mucopolysaccharidosis IIIB in the open field and home cage environments

(2011) A. Langford-Smith et al.   GENES BRAIN AND BEHAVIOR

Mucopolysaccharidosis Type I, Unique Structure of Accumulated Heparan Sulfate and IncreasedN-Sulfotransferase Activity in Mice Lacking α-l-iduronidase

(2011) Rebecca J. Holley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: The positive effect of long-term aspirin treatment

(2011) Audrey Arfi et al.   MOLECULAR GENETICS AND METABOLISM

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

(2011) Jerome Thiery et al.   NATURE IMMUNOLOGY

Prostaglandin E2 Reverses Aberrant Production of an Inflammatory Chemokine by Microglia from Sandhoff Disease Model Mice through the cAMP-PKA Pathway

(2011) Eri Kawashita et al.   PLoS One

Female Mucopolysaccharidosis IIIA Mice Exhibit Hyperactivity and a Reduced Sense of Danger in the Open Field Test

(2011) Alex Langford-Smith et al.   PLoS One

Diagnosis of the mucopolysaccharidoses

(2011) T. J. A. Lehman et al.   RHEUMATOLOGY

Invariant natural killer T cells: bridging innate and adaptive immunity

(2010) Luc Van Kaer et al.   CELL AND TISSUE RESEARCH

Inflammatory cytokines as a third signal for T cell activation

(2010) Julie M Curtsinger et al.   CURRENT OPINION IN IMMUNOLOGY

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

(2010) Alessandro Fraldi et al.   EMBO JOURNAL

A small-molecule inhibitor of macrophage migration inhibitory factor for the treatment of inflammatory disease

(2010) Aaron P. Kithcart et al.   FASEB JOURNAL

Mucopolysaccharidosis I, II, and VI: brief review and guidelines for treatment

(2010) Roberto Giugliani et al.   GENETICS AND MOLECULAR BIOLOGY

Macrophage Migration Inhibitory Factor Increases Leukocyte-Endothelial Interactions in Human Endothelial Cells via Promotion of Expression of Adhesion Molecules

(2010) Q. Cheng et al.   JOURNAL OF IMMUNOLOGY

CD22 Regulates Adaptive and Innate Immune Responses of B Cells

(2010) Norihito Kawasaki et al.   Journal of Innate Immunity

The role of monocyte chemoattractant protein MCP1/CCL2 in neuroinflammatory diseases

(2010) Grégory Conductier et al.   JOURNAL OF NEUROIMMUNOLOGY

Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response

(2010) Smruti Killedar et al.   Journal of Neuroinflammation

Respiratory Manifestations in Mucopolysaccharidoses

(2010) Marianne S. Muhlebach et al.   Paediatric Respiratory Reviews

Autophagosome formation in mammalian cells

(2010) Chloe Burman et al.   Seminars in Immunopathology

Mucopolysaccharidosis IIIB: Oxidative damage and cytotoxic cell involvement in the neuronal pathogenesis

(2009) Guglielmo R.D. Villani et al.   BRAIN RESEARCH

Alterations in Oxidative Markers in the Cerebellum and Peripheral Organs in MPS I Mice

(2009) Gustavo Kellermann Reolon et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Natural Killer T Cells and Autoimmune Disease

(2009) Lan Wu et al.   CURRENT MOLECULAR MEDICINE

Development and maturation of invariant NKT cells in the presence of lysosomal engulfment

(2009) Tiziana Plati et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TLR2 Engagement on Dendritic Cells Promotes High Frequency Effector and Memory CD4 T Cell Responses

(2009) S. S. Chandran et al.   JOURNAL OF IMMUNOLOGY

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology

Role of microglia in neuronal degeneration and regeneration

(2009) Lisa Walter et al.   Seminars in Immunopathology

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

(2008) M. Quigley et al.   BLOOD

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Inhibits Experimental Autoimmune Thyroiditis by the Expansion of CD4+CD25+Regulatory T Cells

(2008) Su He Wang et al.   ENDOCRINOLOGY

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

(2008) Olivier Joffre et al.   IMMUNOLOGICAL REVIEWS

CD22: an inhibitory enigma

(2008) Jennifer A. Walker et al.   IMMUNOLOGY

Peripheral blood mononuclear cell infiltration and neuroinflammation in the HexB−/− mouse model of neurodegeneration

(2008) Stephanos Kyrkanides et al.   JOURNAL OF NEUROIMMUNOLOGY

Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway

(2008) Teresa F Pais et al.   Journal of Neuroinflammation

Innate and adaptive immune activation in the brain of MPS IIIB mouse model

(2008) Julianne DiRosario et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Brain inflammation and adult neurogenesis: The dual role of microglia

(2008) C.T. Ekdahl et al.   NEUROSCIENCE

Mucopolysaccharidosis I: Management and Treatment Guidelines

(2008) J. Muenzer et al.   PEDIATRICS

Early Neurodegeneration Progresses Independently of Microglial Activation by Heparan Sulfate in the Brain of Mucopolysaccharidosis IIIB Mice

(2008) Jérôme Ausseil et al.   PLoS One

Mast cells possess distinct secretory granule subsets whose exocytosis is regulated by different SNARE isoforms

(2008) N. Puri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of CD28 expression on CD8+ T cells by CTLA-4

(2007) M. Berg et al.   JOURNAL OF LEUKOCYTE BIOLOGY