期刊
JOURNAL OF INFECTIOUS DISEASES
卷 210, 期 4, 页码 593-596出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiu131
关键词
bacterial vaginosis; multi-species biofilm; virulence determination
资金
- European Union (FEDER/COMPETE funds)
- Fundacao para a Ciencia e a Tecnologia [FCOMP-01-0124-FEDER-008991 [PTDC/BIA-MIC/098228/2008], RECI/EBB-EBI/0179/2012 [FCOMP-01-0124-FEDER-027462]]
Despite the worldwide prevalence of bacterial vaginosis (BV), its etiology is still unknown. Although BV has been associated with the presence of biofilm, the ability of BV-associated bacteria to form biofilms is still largely unknown. Here, we isolated 30 BV-associated species and characterized their virulence, using an in vitro biofilm formation model. Our data suggests that Gardnerella vaginalis had the highest virulence potential, as defined by higher initial adhesion and cytotoxicity of epithelial cells, as well as the greater propensity to form a biofilm. Interestingly, we also demonstrated that most of the BV-associated bacteria had a tendency to grow as biofilms.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据