Article
Medicine, General & Internal
Chirag G. Patel, Guoyu Tao
Summary: This study estimated the testing rates for gonorrhea, chlamydia, syphilis, and HIV, as well as the prevalence of chlamydia and gonorrhea among patients with high-risk sexual relationships. The findings suggest suboptimal screening for sexually transmitted infections in this patient population, highlighting the need for STI counseling, testing, and treatment.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Andrea K. Knittel, Jacqueline E. Rudolph, Bonnie E. Shook-Sa, Andrew Edmonds, Catalina Ramirez, Mardge Cohen, Tonya Taylor, Adebola Adedimeji, Katherine G. Michel, Joel Milam, Jennifer Cohen, Jessica D. Donohue, Antonina Foster, Margaret Fischl, Dustin M. Long, Adaora A. Adimora
Summary: Women in the United States who have been incarcerated report higher rates of sexual risk behavior and sexually transmitted infections; the study found that incarceration increases the incidence of first incident STIs; therefore, women who have recently experienced incarceration may be at increased risk of STIs.
JOURNAL OF WOMENS HEALTH
(2022)
Article
Immunology
Jayalakshmi Ravindran, Barbra A. Richardson, John Kinuthia, Jennifer A. Unger, Alison L. Drake, Lusi Osborn, Daniel Matemo, Janna Patterson, R. Scott McClelland, Grace John-Stewart
Summary: This study found that sexually transmitted infections and incident HIV during pregnancy are predictors of preterm birth in Kenya, suggesting the need for earlier treatment and interventions to decrease genital inflammation.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Public, Environmental & Occupational Health
Achangwa Chiara, Sukhyun Ryu, Jae-Heon Jung, Se-Min Hwang
Summary: The COVID-19 pandemic has led to a decrease in chlamydia infections in South Korea, especially among males. There is a need to strengthen surveillance and response measures for sexually transmitted infections.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Alison Swaims-Kohlmeier, Anandi N. Sheth, Jed Brody, Felicia P. Hardnett, Sunita Sharma, Erin Wells Bonning, Igho Ofotokun, Ivana Massud, J. Gerardo Garcia-Lerma
Summary: The menstrual cycle influences HIV susceptibility by driving periodic shifts in immune landscape and recruitment of CCR5+ CD4 T cells, which are bystander cells for HIV infection. The study found that macaques and healthy women exhibit similar type-1 inflammatory T cell responses over the menstrual cycle, impacting HIV vulnerability.
Article
Immunology
Maria C. Geba, Samuel Powers, Brooke Williams, Kathryn R. Dort, Elizabeth T. Rogawski McQuade, Kathleen A. McManus
Summary: This study examined the implementation of multisite screening for sexually transmitted infections (STIs) in HIV-infected individuals. The results indicated that there were deficiencies in the documentation of sexual history and the rate of STI screening. STIs were more frequently diagnosed in Hispanic males and those with detectable HIV viral loads. Multisite screening identified a higher number of extragenital STIs compared to screening at genital sites only.
OPEN FORUM INFECTIOUS DISEASES
(2022)
Article
Public, Environmental & Occupational Health
Eline L. M. Op de Coul, Demi Peek, Yolanda W. M. van Weert, Servaas A. Morre, Ingrid Rours, Chantal Hukkelhoven, Ank de Jonge, Birgit van Benthem, Monique Pereboom
Summary: Antenatal screening for HIV, syphilis and HBV has been successfully implemented in The Netherlands, but data on other STI among pregnant women or male partners are limited. The study aimed to assess the prevalence of Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), and Trichomonas vaginalis (TV) among pregnant women and male partners, identify risk factors for these STI during pregnancy, and identify adverse perinatal outcomes associated with STI. The results showed a low prevalence of STI in pregnant women and male partners, except for CT in young women, and the study was unable to confirm previous associations between STI and adverse perinatal outcomes, likely due to the low prevalence of STI and small study sample.
REPRODUCTIVE HEALTH
(2021)
Review
Chemistry, Multidisciplinary
Juliette Moriceau, Amandine Fevre, Diego Dominguez-Balmaseda, Angel Gonzalez-de-la-Flor, Julia Simon-Areces, Guillermo Garcia-Perez-de-Sevilla
Summary: Women are more prone to ACL injuries than men, and the menstrual cycle appears to influence knee laxity in women. However, it is unclear whether there is a correlation between the menstrual cycle and the risk of ACL injury.
APPLIED SCIENCES-BASEL
(2022)
Article
Infectious Diseases
Laura Villa, Jose Antonio Boga, Luis Otero, Fernando Vazquez, Ana Milagro, Paula Salmeron, Marti Vall-Mayans, Maria Dolores Macia, Samuel Bernal, Luis Pineiro
Summary: This multicentre project aimed to study the susceptibility of C. trachomatis to antimicrobials in isolates from patients with treatment failure. The study found that all the isolates were sensitive to azithromycin and doxycycline and no mutations associated with resistance were detected. The results indicate the absence of genomic resistance in this dataset.
Article
Immunology
Alexis J. Bick, Chanel Avenant, Michele Tomasicchio, Zephne van der Spuy, Janet P. Hapgood
Summary: Both luteal phase progesterone levels and the use of the progestin-only contraceptive depo-medroxyprogesterone acetate (DMPA-IM) have been linked to increased S/HIV acquisition. The mechanisms underlying these associations are not well understood. This study found that DMPA-IM increases HIV-1 infection in a different manner than luteal phase hormones, involving the glucocorticoid receptor and changes in CCR5 and CD69 expression.
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
(2022)
Article
Physiology
Ritva S. Taipale-Mikkonen, Anna Raitanen, Anthony C. Hackney, Guro Strom Solli, Maarit Valtonen, Heikki Peltonen, Kerry McGawley, Heikki Kyrolainen, Johanna K. Ihalainen
Summary: The study found that fluctuations in menstrual cycle and hormonal contraceptive cycle do not systematically affect physiological variables monitored during incremental treadmill testing. However, differences in heart rate at AerT and AnaT between EUM and CHC groups suggest that heart rate-based training should be individually prescribed, and recording of MC or HC use during testing is important to explain potential minor changes in variables such as lactate concentrations or HR response.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Sari L. Reisner, David R. Pletta, Dana J. Pardee, Madeline B. Deutsch, Sarah M. Peitzmeier, Jaclyn M. W. Hughto, Meg Quint, Jennifer Potter
Summary: The study describes the development, piloting, and refinement of a digitally deployed measure to assess self-reported sexual behaviors associated with HIV and STI transmission for research with transmasculine adults. The measure successfully integrates gender-affirming language and branching logic to capture a wide array of sexual behaviors, providing necessary data to assess risk behaviors for HIV and STI transmission.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Virology
Partha K. Chandra, Stephen E. Braun, Sudipa Maity, Jorge A. Castorena-Gonzalez, Hogyoung Kim, Jeffrey G. Shaffer, Sinisa Cikic, Ibolya Rutkai, Jia Fan, Jessie J. Guidry, David K. Worthylake, Chenzhong Li, Asim B. Abdel-Mageed, David W. Busija
Summary: Despite cART's suppression of HIV replication, a significant number of HIV-infected individuals still suffer from HIV-associated neurocognitive disorders (HAND). This study investigated the role of exosomes in HIV infection in the central nervous system (CNS). The findings suggest that circulating exosomal proteins, particularly those expressed by CNS cells, may play a role in viral reactivation and neuropathogenesis, shedding light on the etiology of HAND.
Article
Oncology
Zhihai Ma, Baback Gharizadeh, Xingsheng Cai, Mengzhen Li, Maria Dolores Fellner, Jorge Alejandro Basiletti, Rita Mariel Correa, Maria Celeste Colucci, Gabriela Baldoni, Martin Vacchino, Patricia Galarza, Maria Alejandra Picconi, Chunlin Wang
Summary: Sexually transmitted infections (STIs) are widespread and have a significant impact on individual health and public health systems worldwide. The HPV-STI ChapterDx Next Generation Sequencing (NGS) assay can detect and quantify multiple types of HPV and STIs, providing user-friendly, automated, and cost-effective results.
INFECTIOUS AGENTS AND CANCER
(2022)
Review
Public, Environmental & Occupational Health
Jessica Leston, Hannah Wenger, Brigg Reilley, Stephanie Craig Rushing, Elizabeth Rink, Hannah Warren, Jean Howe, Paul Bloomquist, Tina Tah, Itai Jeffries, Jonathan Iralu, Phoebe Thorpe, Andria Apostolou, Melanie M. Taylor
Summary: This review examines the burden of sexual health and sexually transmitted infections (STIs) among American Indian/Alaska Native (AI/AN) populations in the United States. The findings suggest that AI/AN populations carry a disproportionate burden of STIs compared to non-Hispanic Whites, with historical trauma and social determinants of health contributing to the risk. While STI services are available, barriers to care exist. Community-based sexual health programming has shown success, but has primarily focused on adolescents and young adults. The review highlights the need for integrated, low-barrier STI prevention and treatment services that are culturally relevant and acknowledge AI/AN histories and cultures.
Article
Microbiology
Yetunde F. Fakile, Heather Jost, Karen W. Hoover, Kathleen J. Gustafson, Susan M. Novak-Weekley, Jeff M. Schapiro, Anthony Tran, Joan M. Chow, Ina U. Park
JOURNAL OF CLINICAL MICROBIOLOGY
(2018)
Article
Immunology
Cassandra Tansey, Chunxia Zhao, Andre Hopkins, Jana M. Ritter, Yetunde F. Fakile, Allan Pillay, Samantha S. Katz, Lara Pereira, James Mitchell, Frank Deyounks, Ellen N. Kersh, Janet M. McNicholl, Sundaram Ajay Vishwanathan
JOURNAL OF INFECTIOUS DISEASES
(2018)
Article
Immunology
Ina U. Park, Yetunde F. Fakile, Joan M. Chow, Kathleen J. Gustafson, Heather Jost, Jeffrey M. Schapiro, Susan Novak-Weekley, Anthony Tran, Jim H. Nomura, Victor Chen, Manie Beheshti, Townson Tsai, Karen Hoover, Gail Bolan
CLINICAL INFECTIOUS DISEASES
(2019)
Article
Microbiology
Lara E. Pereira, Joshua McCormick, Tandin Dorji, Joseph Kang, Yongcheng Sun, Mayur Shukla, Andre Hopkins, John Deutsch, Ellen N. Kersh, Kyle Bernstein, Yetunde F. Fakile
JOURNAL OF CLINICAL MICROBIOLOGY
(2018)
Letter
Virology
Weiming Zhu, Kimberly Mumby, Doreen Dankerlui, Jake Manteuffel, Cal Ham, Ya-lin A. Huang, Philip J. Peters, Yetunde F. Fakile, Norman Markowitz, Karen W. Hoover
JOURNAL OF CLINICAL VIROLOGY
(2018)
Article
Immunology
Scott W. Olesen, Elizabeth A. Torrone, John R. Papp, Robert D. Kirkcaldy, Marc Lipsitch, Yonatan H. Grad
JOURNAL OF INFECTIOUS DISEASES
(2019)
Article
Public, Environmental & Occupational Health
William S. Pearson, Kristen Kreisel, Thomas A. Peterman, Maria Zlotorzynska, Patricia J. Dittus, Melissa A. Habel, John R. Papp
PREVENTIVE MEDICINE
(2018)
Article
Public, Environmental & Occupational Health
K. Gupta, R. K. Bakshi, B. Van Der Pol, G. Daniel, L. Brown, C. G. Press, R. Gorwitz, J. Papp, J. Y. Lee, W. M. Geisler
EPIDEMIOLOGY AND INFECTION
(2019)
Article
Infectious Diseases
Yetunde F. Fakile, Myra Brinson, Victoria Mobley, Ina U. Park, Anne M. Gaynor
SEXUALLY TRANSMITTED DISEASES
(2019)
Article
Infectious Diseases
Yetunde F. Fakile, Norman Markowitz, Weiming Zhu, Kimberly Mumby, Doreen Dankerlui, Josh K. McCormick, David C. Ham, Andre Hopkins, Jake Manteuffel, Yongcheng Sun, Ya-lin A. Huang, Philip J. Peters, Karen W. Hoover
SEXUALLY TRANSMITTED DISEASES
(2019)
Article
Public, Environmental & Occupational Health
Michelle L. Johnson Jones, Johanna Chapin-Bardales, Destani Bizune, John R. Papp, Christi Phillips, Robert D. Kirkcaldy, Cyprian Wejnert, Kyle T. Bernstein, Salma Khuwaja, Zaida Lopez, Paige Padgett, David Forrest, Willie Nixon, Emma Spencer, Sarah Braunstein, Sidney Carrillo, Alexis Rivera, Theresa Ick, H. Fisher Raymond, Jenevieve Opoku, Irene Kuo
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2019)
Article
Medicine, General & Internal
Andre O. Hopkins, Trinh Thuy, Yetunde F. Fakile, Allan Pillay, Melanie M. Taylor, Ellen Kersh, Mary Kamb
Review
Health Care Sciences & Services
Casey E. Copen, Julie Rushmore, Alex De Voux, Robert D. Kirkcaldy, Yetunde F. Fakile, Carla Tilchin, Jessica Duchen, Jacky M. Jennings, Morgan Spahnie, Abigail Norris Turner, William C. Miller, Richard M. Novak, John A. Schneider, Andrew B. Trotter, Kyle T. Bernstein
Summary: In the United States, rates of primary and secondary syphilis have been increasing rapidly among men who have sex with men (MSM). This study aimed to collect longitudinal data on sexual behaviors and sexually transmitted infections (STIs) among MSM in order to understand factors related to syphilis transmission and acquisition. A prospective cohort of 748 MSM in three US cities was enrolled, and participants completed behavioral questionnaires and STI testing at quarterly visits. The data from this study will inform interventions to prevent syphilis in high-burden areas.
JMIR RESEARCH PROTOCOLS
(2022)
Meeting Abstract
Infectious Diseases
Mayur Shukla, Yongcheng Sun, Joshua Mccormick, Andre Hopkins, Lara Pereira, Anne Gaynor, Ellen Kersh, Yetunde Fakile
SEXUALLY TRANSMITTED INFECTIONS
(2019)
Article
Medicine, General & Internal
Yasaman Zia, Jeffrey Wiener, Margaret Christine Snead, John Papp, Christi Phillips, Lisa Flowers, Natalie Medley-Singh, Elizabeth C. Costenbader, Tina Hylton-Kong, Athena P. Kourtis