Article
Multidisciplinary Sciences
Joseph D. Challenger, Daniela Olivera Mesa, Dari F. Da, R. Serge Yerbanga, Thierry Lefevre, Anna Cohuet, Thomas S. Churcher
Summary: Transmission-blocking vaccines for malaria are being tested and their field efficacy is predicted to be higher than in laboratory conditions. Targeting school-aged children is recommended as it can have a significant impact in reducing malaria cases. Utilizing such vaccines alongside existing interventions could have substantial benefits in malaria control.
NATURE COMMUNICATIONS
(2021)
Article
Public, Environmental & Occupational Health
Ning Zhao, Ishaq Sesay, Hong Tu, Frederick Yamba, Liang Lu, Yuhong Guo, Xiuping Song, Jun Wang, Xiaobo Liu, Yujuan Yue, Haixia Wu, Qiyong Liu
Summary: The study identified An. gambiae as the dominant Anopheles species in Freetown, Sierra Leone, with An. gambiae s.s. being the predominant species within the An. gambiae complex. Surveillance of seasonal fluctuation and high P. falciparum infection rates in Anopheles suggest that June to July and October to November are crucial periods for malaria control and prevention. The high frequency of kdr allele mutations in An. gambiae calls for close monitoring of vector susceptibility to insecticides and tracking of resistance mechanisms to develop more effective vector control measures and strategies.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Entomology
Naminata Tondossama, Chiara Virgillito, Zanakoungo Ibrahima Coulibaly, Verena Pichler, Ibrahima Dia, Alessandra della Torre, Andre Offianan Toure, Akre Maurice Adja, Beniamino Caputo, Rui-De Xue
Summary: Despite high usage of insecticide-treated bed nets, malaria transmission rates remain high in two studied villages, possibly due to mosquito and human behaviors.
Article
Multidisciplinary Sciences
Prisca S. L. Pare, Domonbabele F. D. S. Hien, Koama Bayili, Rakiswende S. Yerbanga, Anna Cohuet, David Carrasco, Edwige Guissou, Louis-Clement Gouagna, Koudraogo B. Yameogo, Abdoulaye Diabate, Rickard Ignell, Roch K. Dabire, Thierry Lefevre, Olivier Gnankine
Summary: This study aimed to assess the effect of plant sugar feeding on the response of Anopheles gambiae to insecticides. The findings suggest that plant diet significantly influenced mosquito's susceptibility to insecticides and the effects may be driven by a direct effect of plant diet on mosquito survival rather than indirect effects through interference with insecticide-resistance mechanisms.
SCIENTIFIC REPORTS
(2022)
Article
Parasitology
Domonbabele F. D. S. Hien, Prisca S. L. Pare, Amanda Cooper, Benjamin K. Koama, Edwige Guissou, Koudraogo B. Yameogo, Rakiswende S. Yerbanga, Iain W. Farrell, Jean B. Ouedraogo, Olivier Gnankine, Rickard Ignell, Anna Cohuet, Roch K. Dabire, Philip C. Stevenson, Thierry Lefevre
Summary: The study shows that certain plant compounds in nectar can affect the lifespan of mosquitoes and the infection rate of parasites, but the effects of ricinine at different concentrations vary between the two species of mosquitoes.
PARASITES & VECTORS
(2021)
Article
Parasitology
Brenda Oseno, Faith Marura, Rodney Ogwang, Martha Muturi, James Njunge, Irene Nkumama, Robert Mwakesi, Kennedy Mwai, Martin K. Rono, Ramadhan Mwakubambanya, Faith Osier, James Tuju
Summary: This study evaluates the utility of IgG responses to members of the Anopheles gambiae D7 protein family as serological markers of human-vector contact. The results show that the D7L2 salivary antigen has great potential as a biomarker of exposure to mosquito bites and as a tool for assessing the efficacy of vector control strategies.
PARASITES & VECTORS
(2022)
Article
Parasitology
Lorenz M. Hofer, Prisca A. Kweyamba, Rajabu M. Sayi, Mohamed S. Chabo, Sonali L. Maitra, Sarah J. Moore, Mgeni M. Tambwe
Summary: This study evaluated the performance of malaria rapid diagnostic tests (mRDTs), light microscopy (LM) and quantitative polymerase chain reaction (qPCR) in detecting asymptomatic malaria infections that can transmit to mosquitoes. The results showed that mRDT detected the highest infection rate, while subpatent mRDT infections contributed marginally to the pool of oocyts-infected mosquitoes.
PARASITES & VECTORS
(2023)
Article
Parasitology
Brian B. Tarimo, Vincent O. Nyasembe, Billy Ngasala, Christopher Basham, Isaack J. Rutagi, Meredith Muller, Srijana B. Chhetri, Rebecca Rubinstein, Jonathan J. Juliano, Mwajabu Loya, Rhoel R. Dinglasan, Jessica T. Lin, Derrick K. Mathias
Summary: This study discovered that Plasmodium ovale has a prevalence of 4-15% among asymptomatic individuals in coastal Tanzania, making it difficult to detect using field diagnostics. P. ovale has a different seasonal peak compared to co-endemic P. falciparum, the ability to relapse, and efficient transmission to Anopheles vectors, which contribute to its persistence amid control efforts focused on P. falciparum.
PARASITES & VECTORS
(2022)
Article
Immunology
Hongying Zhang, Mingqiang Li, Ruixiang Tan, Changsheng Deng, Bo Huang, Zhibin Wu, Shaoqing Zheng, Wenfeng Guo, Fei Tuo, Yueming Yuan, Carlos Alberto Bandeira, D'almeida Herodes Rompao, Qin Xu, Jianping Song, Qi Wang
Summary: Malaria is a serious parasitic disease that kills thousands of people annually, particularly in Africa. Sao Tome and Principe have stable transmission of malaria, but local Anopheles gambiae mosquitoes show resistance to insecticides like DDT and fenitrothion. This resistance status, especially to cypermethrin, is concerning and requires serious consideration by the government for future malaria vector management.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Microbiology
Gunjan Arora, Andaleeb Sajid, Yu-Min Chuang, Yuemei Dong, Akash Gupta, Kristen Gambardella, Kathleen DePonte, Lionel Almeras, George Dimopolous, Erol Fikrig
Summary: Malaria is a vector-borne disease caused by Plasmodium sporozoites, and mosquito saliva proteins can influence pathogen transmission and early infection. Anopheles gambiae Sporozoite-Associated Protein (AgSAP) interacts directly with Plasmodium sporozoites, inhibits inflammatory responses, and plays a role in early infection modulation. Individuals in endemic malaria regions generate antibodies against AgSAP, suggesting its potential as a biomarker for disease prevalence and epidemiological analysis.
Article
Plant Sciences
Gervais Mouthe Happi, Pamela Kemda Nangmo, Liliane Clotide Dzouemo, Sorelle Fotsing Kache, Ariane Dolly Kenmogne Kouam, Jean Duplex Wansi
Summary: Meliaceae plants are important herbal sources for treating malaria in traditional African medicine. Studies have found significant antiplasmodial and insecticidal activities in this plant family, suggesting their potential as eco-friendly pesticides.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
O. Sy, P. C. Sarr, B. S. Assogba, M. Ndiaye, A. K. Dia, A. Ndiaye, M. A. Nourdine, O. K. Gueye, L. Konate, O. Gaye, O. Faye, E. A. Niang
Summary: Malaria transmission has been significantly reduced in central western Senegal due to effective control interventions, but residual transmission persists in certain areas, possibly due to the increase and spread of insecticide resistance genes among natural malaria vectors populations. Proper assessment of insecticide resistance is crucial for understanding and addressing residual transmission.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2021)
Article
Immunology
Manon Alkema, Isaie J. Reuling, Gerdie M. de Jong, Kjerstin Lanke, Luc E. Coffeng, Geert-Jan van Gemert, Marga van de Vegte-Bolmer, Quirijn de Mast, Reinout van Crevel, Karen Ivinson, Christian F. Ockenhouse, James S. McCarthy, Robert Sauerwein, Katharine A. Collins, Teun Bousema
Summary: The study found that the method of infection through mosquito bites or induced blood-stage malaria has a significant impact on gametocyte production, despite similar asexual parasite densities. The findings suggest that induced blood-stage malaria may be more conducive to gametocyte production compared to mosquito bites.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Immunology
Jianhai Yin, Frederick Yamba, Canjun Zheng, Shuisen Zhou, Samuel Juana Smith, Lili Wang, Hongmei Li, Zhigui Xia, Ning Xiao
Summary: Multiple mutations involved in insecticide resistance in An. gambiae populations in Sierra Leone were detected in the kdrW, A296G rdl, and ace-1 alleles in the present study. It is necessary to monitor vector susceptibility levels to insecticides used in this country and update the insecticide resistance monitoring and management strategy.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Infectious Diseases
Jean Baptiste Yaro, Alfred B. Tiono, Antoine Sanou, Hyacinthe K. Toe, John Bradley, Alphonse Ouedraogo, Z. Amidou Ouedraogo, Moussa W. Guelbeogo, Efundem Agboraw, Eve Worrall, N. 'Fale Sagnon, Steven W. Lindsay, Anne L. Wilson
Summary: The study revealed that having a metal roof on the child's sleeping space was associated with fewer malaria vectors inside the home, with a 45% lower rate compared to thatch roofs. Improvements in house construction, including installation of metal roofs, should be considered in endemic areas of Africa to reduce the burden of malaria.
Article
Genetics & Heredity
Xavier Grau-Bove, Eric Lucas, Dimitra Pipini, Emily Rippon, Arjen E. van 't Hof, Edi Constant, Samuel Dadzie, Alexander Egyir-Yawson, John Essandoh, Joseph Chabi, Luc Djogbenou, Nicholas J. Harding, Alistair Miles, Dominic Kwiatkowski, Martin J. Donnelly, David Weetman
Summary: Research has shown that controlling mosquito populations is crucial for reducing malaria transmission in Africa. Resistance to the insecticide pirimiphos-methyl is primarily caused by mutations in a specific gene. These mutations are present in certain populations and have spread to other populations through inter-specific hybridization.
Correction
Infectious Diseases
Catherine L. Moyes, John Vontas, Ademir J. Martins, Lee Ching Ng, Sin Ying Koou, Isabelle Dusfour, Kamaraju Raghavendra, Joao Pinto, Vincent Corbel, Jean-Philippe David, David Weetman
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Agronomy
Julien Cattel, Marine Minier, Nausicaa Habchi-Hanriot, Morgane Pol, Frederic Faucon, Thierry Gaude, Pascal Gaborit, Jean Issaly, Emma Ferrero, Fabrice Chandre, Nicolas Pocquet, Jean-Philippe David, Isabelle Dusfour
Summary: Insecticide resistance to deltamethrin can vary over time, and different populations carrying resistant alleles at different frequencies respond differently to selection scenarios, which can affect resistance levels and marker frequencies. Avoiding deltamethrin spraying is likely to fail when resistant allele frequencies are high and the associated fitness cost of resistance is low.
PEST MANAGEMENT SCIENCE
(2021)
Article
Public, Environmental & Occupational Health
Akre M. Adja, Dounin D. Zoh, Andre B. Sagna, Didier M. S. Kpan, Negnorogo Guindo-Coulibaly, Ahoua Yapi, Fabrice Chandre
Summary: The research indicates the risk of malaria transmission in the city of Bouake, although the infection rates are low. The study reveals that there is a possibility of malaria transmission in certain areas of the city.
VECTOR-BORNE AND ZOONOTIC DISEASES
(2021)
Article
Biology
Stephane Perrier, Eleonore Moreau, Caroline Deshayes, Marine El-Adouzi, Delphine Goven, Fabrice Chandre, Bruno Lapied
Summary: Researchers found that nAChRs and intracellular calcium concentration provide a compensatory mechanism for the neurons of two resistant mosquito strains, AcerKis and KdrKis, to insecticide exposure.
COMMUNICATIONS BIOLOGY
(2021)
Correction
Evolutionary Biology
Vivek Jayaswal, Cyrille Ndo, Hsiu-Ching Ma, Bryan D. Clifton, Marco Pombi, Kevin Cabrera, Anna Cohuet, Karine Mouline, Abdoulaye Diabate, Roch Dabire, Diego Ayala, Jose M. Ranz
GENOME BIOLOGY AND EVOLUTION
(2022)
Review
Parasitology
Thierry Lefevre, Nicolas Sauvion, Rodrigo P. P. Almeida, Florence Fournet, Haoues Alout
Summary: This review discusses the importance of vector management and highlights the impact of reducing or eliminating vector populations on ecosystem functioning. Using examples from various vector species, it emphasizes that changes in vector abundance alter biotic interactions and are unlikely to be neutral in terms of ecosystem functioning.
TRENDS IN PARASITOLOGY
(2022)
Article
Chemistry, Applied
F. Ghernaouti, A. Perrin, J. Causse, F. Chandre, D. Cornu, J. Cambedouzou
Summary: Encapsulation of active substances in biopolymer beads is a widely used method, and the characterization of these aqueous materials in their early stage of production is crucial. This study utilized small angle x-ray scattering (SAXS) as a tool to determine the specific surface area (SSA) of alginate microbeads in solution. The results show that SAXS can be a valuable tool for extracting dimensional and textural information of hydrogels during the formulation process.
FOOD HYDROCOLLOIDS
(2022)
Article
Parasitology
Donald Hessou-Djossou, Innocent Djegbe, Koffi Mensah Ahadji-Dabla, Odilon M. Nonfodji, Genevieve Tchigossou, Rousseau Djouaka, Sylvie Cornelie, Luc Djogbenou, Martin Akogbeto, Fabrice Chandre
Summary: The study identified multiple breeding sites of Anopheles in urban areas of Benin created through human activities, and found associations between larval density and environmental factors such as temperature, dissolved oxygen, and faecal coliform load.
PARASITES & VECTORS
(2022)
Article
Infectious Diseases
Camille Lacroux, Emmanuelle Pouydebat, Marie Rossignol, Sophie Durand, Alfred Aleeje, Edward Asalu, Fabrice Chandre, Sabrina Krief
Summary: Chimpanzees may choose specific tree species to avoid mosquito bites.
Letter
Multidisciplinary Sciences
Carlo Costantini, Fabrice Chandre, Vincent Corbel, Nicolas Moiroux, Frederic Simard, Claire Sangbakembi-Ngounou, Diego Ayala
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Parasitology
Vincent Corbel, Mara D. Kont, Martha Liliana Ahumada, Laura Andreo, Bazoma Bayili, Koama Bayili, Basil Brooke, Jesus A. Pinto Caballero, Ben Lambert, Thomas S. Churcher, Stephane Duchon, Josiane Etang, Adriana E. Flores, Kasinathan Gunasekaran, Waraporn Juntarajumnong, Matt Kirby, Rachel Davies, Rosemary Susan Lees, Audrey Lenhart, Jose Bento Pereira Lima, Ademir J. Martins, Pie Mueller, Raphael N'Guessan, Corine Ngufor, Giorgio Praulins, Martha Quinones, Kamaraju Raghavendra, Vaishali Verma, Adanan Che Rus, Michael Samuel, Koou Sin Ying, Sungsit Sungvornyothin, Sreehari Uragayala, Raman Velayudhan, Rajpal S. Yadav
Summary: This study developed and validated a new WHO glass bottle bioassay method to monitor mosquito susceptibility to new public health insecticides. The results showed that the bottle bioassay is an effective method for evaluating mosquito susceptibility to new and promising insecticides.
PARASITES & VECTORS
(2023)
Article
Entomology
James Devillers, Jean-Philippe David, Benoit Barres, Haoues Alout, Bruno Lapied, Sebastien Chouin, Isabelle Dusfour, Catherine Billault, Farida Mekki, Isabelle Attig, Vincent Corbel
Summary: The present work proposes an integrated plan of resistance surveillance in France and in the French Overseas territories to provide appropriate responses to the situation. The plan includes periodic monitoring of insecticide resistance at the population level using various approaches and a stratification of resistance risk at the territory level to adjust surveillance and vector control actions.
Article
Entomology
Yeyinou Laura Estelle Loko, Sedami Medegan Fagla, Parfait Kassa, Coffi Ayide Ahouansou, Joelle Toffa, Bienvenu Glinma, Victorien Dougnon, Omedine Koukoui, Salako Luc Djogbenou, Manuele Tamo, Fernand Gbaguidi
Summary: The study evaluated the chemical composition and biological effects of essential oils from Cymbopogon citratus and Cymbopogon nardus against the pest D. porcellus. Results showed that these oils were more effective as repellents and fumigants compared to the commercial insecticide, but had lower contact toxicity.
INTERNATIONAL JOURNAL OF TROPICAL INSECT SCIENCE
(2021)
