Changes in Malaria Parasite Drug Resistance in an Endemic Population Over a 25-Year Period With Resulting Genomic Evidence of Selection

Differences in selective pressure on dhps and dhfr drug resistant mutations in western Kenya

(2012) Andrea M McCollum et al.   MALARIA JOURNAL

SNP Genotyping Identifies New Signatures of Selection in a Deep Sample of West African Plasmodium falciparum Malaria Parasites

(2012) Alfred Amambua-Ngwa et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genomic Sequencing of Plasmodium falciparum Malaria Parasites from Senegal Reveals the Demographic History of the Population

(2012) Hsiao-Han Chang et al.   MOLECULAR BIOLOGY AND EVOLUTION

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

(2012) Magnus Manske et al.   NATURE

A Longitudinal Trial Comparing Chloroquine as Monotherapy or in Combination with Artesunate, Azithromycin or Atovaquone-Proguanil to Treat Malaria

(2012) Miriam K. Laufer et al.   PLoS One

Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite

(2012) D. J. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Population Genomic Scan for Candidate Signatures of Balancing Selection to Guide Antigen Characterization in Malaria Parasites

(2012) Alfred Amambua-Ngwa et al.   PLoS Genetics

Adaptive evolution and fixation of drug-resistant Plasmodium falciparum genotypes in pregnancy-associated malaria: 9-year results from the QuEERPAM study

(2011) Steve M. Taylor et al.   INFECTION GENETICS AND EVOLUTION

Limited Geographical Origin and Global Spread of Sulfadoxine-Resistant dhps Alleles in Plasmodium falciparum Populations

(2011) Toshihiro Mita et al.   JOURNAL OF INFECTIOUS DISEASES

The evolution of pyrimethamine resistant dhfr in Plasmodium falciparum of south-eastern Tanzania: comparing selection under SP alone vs SP+artesunate combination

(2011) Allen L Malisa et al.   MALARIA JOURNAL

A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon

(2011) Matthias Frank et al.   MALARIA JOURNAL

Randomized Trial of Safety and Effectiveness of Chlorproguanil-Dapsone and Lumefantrine-Artemether for Uncomplicated Malaria in Children in The Gambia

(2011) Samuel Dunyo et al.   PLoS One

Five Years of Large-Scale dhfr and dhps Mutation Surveillance Following the Phased Implementation of Artesunate Plus Sulfadoxine-Pyrimethamine in Maputo Province, Southern Mozambique

(2010) Jaishree Raman et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Plasmodium falciparum Isolates with Increased pfmdr1 Copy Number Circulate in West Africa

(2010) B. Witkowski et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quantifying the Evolution and Impact of Antimalarial Drug Resistance: Drug Use, Spread of Resistance, and Drug Failure over a 12‐Year Period in Papua New Guinea

(2010) Christian Nsanzabana et al.   JOURNAL OF INFECTIOUS DISEASES

Return of Chloroquine‐Susceptible Falciparum Malaria in Malawi Was a Reexpansion of Diverse Susceptible Parasites

(2010) Miriam K. Laufer et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial

(2010) Antoinette K Tshefu et al.   LANCET

Continued Decline of Malaria in The Gambia with Implications for Elimination

(2010) Serign J. Ceesay et al.   PLoS One

Environmental, pharmacological and genetic influences on the spread of drug-resistant malaria

(2010) T. Antao et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection

(2010) S. R. Grossman et al.   SCIENCE

Evidence of Selective Sweeps in Genes Conferring Resistance to Chloroquine and Pyrimethamine in Plasmodium falciparum Isolates in India

(2009) T. Mixson-Hayden et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Chloroquine resistance before and after its withdrawal in Kenya

(2009) Leah Mwai et al.   MALARIA JOURNAL

Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria

(2009) Richard J. Pearce et al.   PLOS MEDICINE

Hitchhiking and Selective Sweeps of Plasmodium falciparum Sulfadoxine and Pyrimethamine Resistance Alleles in a Population from Central Africa

(2008) A. M. McCollum et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY