Whole Genome Pyrosequencing of Rare Hepatitis C Virus Genotypes Enhances Subtype Classification and Identification of Naturally Occurring Drug Resistance Variants

Antiviral activity of TMC435 monotherapy in patients infected with HCV genotypes 2–6: TMC435-C202, a phase IIa, open-label study

(2012) Christophe Moreno et al.   JOURNAL OF HEPATOLOGY

Analysis of Hepatitis C Virus Intrahost Diversity across the Coding Region by Ultradeep Pyrosequencing

(2012) M. Lauck et al.   JOURNAL OF VIROLOGY

Preliminary Study of Two Antiviral Agents for Hepatitis C Genotype 1

(2012) Anna S. Lok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Highly Sensitive and Specific Detection of Rare Variants in Mixed Viral Populations from Massively Parallel Sequence Data

(2012) Alexander R. Macalalad et al.   PLoS Computational Biology

Whole Genome Deep Sequencing of HIV-1 Reveals the Impact of Early Minor Variants Upon Immune Recognition During Acute Infection

(2012) Matthew R. Henn et al.   PLoS Pathogens

NS3 protease polymorphism and natural resistance to protease inhibitors in French patients infected with HCV genotypes 1–5

(2011) Sophie Vallet et al.   ANTIVIRAL THERAPY

Telaprevir Alone or With Peginterferon and Ribavirin Reduces HCV RNA in Patients With Chronic Genotype 2 but Not Genotype 3 Infections

(2011) Graham R. Foster et al.   GASTROENTEROLOGY

Genotypic and phenotypic analysis of variants resistant to hepatitis C virus nonstructural protein 5A replication complex inhibitor BMS-790052 in Humans: In Vitro and In Vivo Correlations

(2011) Robert A. Fridell et al.   HEPATOLOGY

Directly acting antivirals against hepatitis C virus

(2011) V. Soriano et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Near-full genome characterization of unclassified hepatitis c virus strains relating to genotypes 1 and 4

(2011) Victoria L. Demetriou et al.   JOURNAL OF MEDICAL VIROLOGY

Origin and Evolution of the Unique Hepatitis C Virus Circulating Recombinant Form 2k/1b

(2011) J. Raghwani et al.   JOURNAL OF VIROLOGY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genetic Heterogeneity of Hepatitis C Virus in Association with Antiviral Therapy Determined by Ultra-Deep Sequencing

(2011) Akihiro Nasu et al.   PLoS One

Naturally occurring genotype 2b/1a hepatitis C virus in the United States

(2011) Dipankar Bhattacharya et al.   Virology Journal

Induced-Fit Binding of the Macrocyclic Noncovalent Inhibitor TMC435 to its HCV NS3/NS4A Protease Target

(2010) Maxwell D. Cummings et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vitro Resistance Profile of the Hepatitis C Virus NS3/4A Protease Inhibitor TMC435

(2010) O. Lenz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

RDP3: a flexible and fast computer program for analyzing recombination

(2010) D. P. Martin et al.   BIOINFORMATICS

Genetic recombination of the hepatitis C virus: clinical implications

(2010) V. Morel et al.   JOURNAL OF VIRAL HEPATITIS

Rapid HCV-RNA Decline With Once Daily TMC435: A Phase I Study in Healthy Volunteers and Hepatitis C Patients

(2009) Henk W. Reesink et al.   GASTROENTEROLOGY

Complete genomic sequences for hepatitis C virus subtypes 4b, 4c, 4d, 4g, 4k, 4l, 4m, 4n, 4o, 4p, 4q, 4r and 4t

(2009) C. Li et al.   JOURNAL OF GENERAL VIROLOGY

Natural Variability of NS3 Protease in Patients Infected with Genotype 4 Hepatitis C Virus (HCV): Implications for Antiviral Treatment Using Specifically Targeted Antiviral Therapy for HCV

(2009) S. Akhavan et al.   JOURNAL OF INFECTIOUS DISEASES

The Evolution of the Major Hepatitis C Genotypes Correlates with Clinical Response to Interferon Therapy

(2009) Phillip S. Pang et al.   PLoS One

Selection of Replicon Variants Resistant to ACH-806, a Novel Hepatitis C Virus Inhibitor with No Cross-Resistance to NS3 Protease and NS5B Polymerase Inhibitors

(2008) W. Yang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients

(2008) Thomas Kuntzen et al.   HEPATOLOGY

Natural Prevalence of Hepatitis C Virus Variants with Decreased Sensitivity to NS3·4A Protease Inhibitors in Treatment‐Naive Subjects

(2008) Doug J. Bartels et al.   JOURNAL OF INFECTIOUS DISEASES

A set of reference sequences for the hepatitis C genotypes 4d, 4f, and 4k covering the full open reading frame

(2008) Thomas Kuntzen et al.   JOURNAL OF MEDICAL VIROLOGY