期刊
JOURNAL OF INFECTION AND CHEMOTHERAPY
卷 16, 期 5, 页码 360-363出版社
SPRINGER TOKYO
DOI: 10.1007/s10156-010-0057-5
关键词
Tuberculosis; Drug resistance; Rifabutin; rpoB; Line probe assay
资金
- Ministry of Health, Labour and Welfare, Japan
We compared rifabutin susceptibility and rpoB mutations in 98 multi-drug-resistant strains of Mycobacterium tuberculosis (MDR-TB) by DNA sequencing and with a line probe assay using the commercially available INNO-LiPA Rif. TB kit (the LiPA). Our results indicated that rifabutin continues to remain active against MDR-TB strains harboring certain genetic alterations and also that the LiPA might be useful in identifying MDR-TB strains susceptible to rifabutin.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据