Article
Chemistry, Multidisciplinary
Hang Yin, Roselyne Rosas, Stephane Viel, Michel Giorgi, Valerie Monnier, Laurence Charles, Didier Siri, Didier Gigmes, Youssef Nassar, Floris Chevallier, Christophe Bucher, Ruibing Wang, Anthony Kermagoret, David Bardelang
Summary: This article describes the structural tunability of cucurbit[8]uril (CB[8]) host/guest complexes and their responsiveness to various stimuli in water. A series of versatile 3:2 host/guest complexes were prepared by combining CB[8] with symmetric, linear diviologens, exhibiting remarkable dynamic properties and external ring translocation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Engineering, Chemical
Ying Wang, Song Zhao, Zhiyuan Zha, Zhi Wang, Jixiao Wang
Summary: A novel host-guest NF membrane based on CB-PEI was designed and fabricated, showing attractive separation performance for monovalent/divalent salts separation, purification and desalination of small molecule solutions.
Article
Chemistry, Multidisciplinary
Hao Chen, Jin Zhang, Wenting Yu, Yi Cao, Zhaozhen Cao, Yebang Tan
Summary: The study demonstrates the control of viscoelasticity of polymer networks by designing crosslinks with variable molecular dynamics, achieving a quantitative control over mechanical properties and reversible mechanical response. This strategy paves the way for engineering smart responsive materials by tailoring the mechanical properties of polymer networks at the molecular level.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Suresh Moorthy, Alvaro Castillo Bonillo, Hugues Lambert, Elina Kalenius, Tung-Chun Lee
Summary: A new supramolecular approach has been reported to selectively deactivate the electrophilic alpha-carbon of phenyl diazonium ion through host-guest complexation, thus avoiding undesirable side reactions. This method holds great potential for the reactive chemistry of organic molecules in aqueous media.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Zhenwen Wang, Lei Mei, Chenxing Guo, Song Huang, Wei-Qun Shi, Xiaowei Li, Wen Feng, Xiaopeng Li, Cheng Yang, Lihua Yuan
Summary: Here we report a ring-in-ring(s) system comprising a hydrogen-bonded macrocycle and cyclobis(paraquat-o-phenylene) tetracation (o-Box) or cyclobis(paraquat-p-phenylene) tetracation (CBPQT(4+), p-Box) that assembles to construct discrete higher order structures with adaptive conformation. This ring-in-ring(s) system features the box-directed aggregation of multiple macrocycles, leading to generation of several stable species such as H4G (1 a/o-Box) and H5G (1 a/o-Box). Remarkably, a dimeric shish-kebab-like ring-in-rings superstructure H7G2 (1 a/o-Box) or H8G2 (1 a/p-Box) is formed from the coaxial stacking of two ring-in-rings units. The formation of such unique dimeric superstructures is attributed to the large pi-surface of this 2D planar macrocycle and the conformational variation of both host and guest.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Chemistry, Multidisciplinary
Ziyi Wang, Chen Sun, Kuikun Yang, Xiaoyuan Chen, Ruibing Wang
Summary: Supramolecular polymers, with their unique features and functions, have attracted broad interest in diverse biomedical applications. This Minireview summarizes the recent progress in the design, fabrication, and biomedical applications of CB[n]-based supramolecular polymers (CSPs), categorized as noncovalent and covalent CSPs. The design principles, advantages, and future perspectives of CSPs in the field of biomedicine are also discussed.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Xue Yang, Qian Cheng, Valerie Monnier, Laurence Charles, Hakim Karoui, Olivier Ouari, Didier Gigmes, Ruibing Wang, Anthony Kermagoret, David Bardelang
Summary: Chemists have successfully mimicked the function of natural molecular machines with synthetic systems in organic solvents and exchanged guest molecules in synthetic macrocycles for the production of pH-responsive hydrogels in water. Cucurbiturils may be excellent ring molecules for the construction of advanced molecular machines working in water.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Xue Yang, Chunyang Li, Michel Giorgi, Didier Siri, Xavier Bugaut, Bastien Chatelet, Didier Gigmes, Mehdi Yemloul, Virginie Hornebecq, Anthony Kermagoret, Sophie Brasselet, Alexandre Martinez, David Bardelang
Summary: Porous organic crystals based on macrocycles have recently shown exceptional sorption and separation properties. In this study, the inclusion of trimethoxybenzyl-azaphosphatrane in the macrocycle cucurbit[8]uril (CB[8]) resulted in the formation of molecular porous host.guest crystals (PHGC-1) with radically new properties. The PHGC-1 crystals demonstrated spontaneous and selective adsorption of iodine at room temperature and atmospheric pressure, offering potential advantages in energy cost reduction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Materials Science, Multidisciplinary
Zheng-Kun Bai, Qing-Mei Ge, Nan Jiang, Hang Cong, Zhu Tao, Mao Liu, Ying Fan
Summary: A novel supramolecular photocatalyst, g-C3N4/ Ag3PO4@Q [7] composite, with the macrocyclic compound of cucurbit [7]uril (Q [7]) block, is successfully prepared by ternary organic-inorganic hybridization. It is applied for the photo-driven degradation of pyroquilon and admire pesticides in the irradiation of visible light. The photocatalyst exhibits high degradation efficiency, stability, and reusability, offering performance advantages of low energy consumption and fast reaction rates compared to reported photocatalysts.
Article
Chemistry, Multidisciplinary
Xin-Kun Ma, Xiaolu Zhou, Jing Wu, Fang-Fang Shen, Yu Liu
Summary: This study presents a design strategy for achieving near-infrared excitation and emission of organic phosphorescence materials through two-stage confinement supramolecular assembly. The prepared water-soluble assemblies maintain two-photon absorption and multicolor luminescence in cells or vivo, providing potential applications in bioimaging.
Article
Nanoscience & Nanotechnology
Han Wu, Hua Wang, Feilong Qi, Tian Xia, Yu Xia, Jiang-Fei Xu, Xi Zhang
Summary: A new strategy of activatable host-guest conjugate with self-inclusion property is proposed for supramolecular chemotherapy, which can achieve high-efficiency drug release triggered by intramolecular host-guest self-inclusion. The encapsulation of oxaliplatin in the conjugate leads to the formation of a stable supramolecular drug, and the release of oxaliplatin in the tumor microenvironment shows comparable anti-tumor bioactivity to naked oxaliplatin. This research may open new horizons for programmable and on-demand supramolecular chemotherapy with high anti-tumor efficiency.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Materials Science, Multidisciplinary
Cheng Xu, Xiang Yu, Yang Liu, Xiongzhi Zhang, Simin Liu
Summary: In this study, multi-functional and stimulus-responsive hydrogels were successfully prepared by a hybrid supramolecular copolymerization strategy. The obtained hydrogels exhibit excellent mechanical properties, self-healing efficiency, and conductivity, as well as a triple stimulation response to strain, heat, and near-infrared light. This versatile hydrogel can function as a wearable strain sensor and has great potential in flexible electronics and biomedical fields.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Bin Yuan, Han Wu, Hua Wang, Bohan Tang, Jiang-Fei Xu, Xi Zhang
Summary: A supramolecular strategy was proposed to regulate the activity of photosensitizers for improved ROS generation efficiency and accelerated self-degradation ability during PDT treatment, leading to reduced dark toxicity and potential side effects.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Yawen Li, Qingfang Li, Xiaran Miao, Chunyan Qin, Dake Chu, Liping Cao
Summary: Achiral supramolecular organic framework (SOF-1) can exhibit adaptive chirality induced by specific compounds in water, leading to mirror-image circular dichroism and circularly polarized luminescence. This adaptive chirality can be utilized for determining the enantiopurity of amino acids and distinguishing biological chiral macromolecules.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Polymer Science
Yilin Li, Yuteng Su, Zhaoxiang Li, Yueyue Chen
Summary: Supramolecular combination therapy utilizes macrocyclic supramolecular materials to design drug delivery systems, improving anticancer efficiency and reducing toxicity to normal tissues, while overcoming the limitations of single-drug chemotherapy.
Article
Chemistry, Medicinal
David Sigwalt, Damien Moncelet, Shane Falcinelli, Vijaybabu Mandadapu, Peter Y. Zavalij, Anthony Day, Volker Briken, Lyle Isaacs
Article
Chemistry, Organic
Wen-Jing Wu, Feng Wu, Anthony I. Day
JOURNAL OF ORGANIC CHEMISTRY
(2017)
Article
Chemistry, Organic
Fangfei Li, Anil K. Gorle, Marie Ranson, Kara L. Vine, Robert Kinobe, Marshall Feterl, Jeffrey M. Warner, F. Richard Keene, J. Grant Collins, Anthony I. Day
ORGANIC & BIOMOLECULAR CHEMISTRY
(2017)
Article
Chemistry, Organic
Yi Zhao, Vijaybabu Mandadapu, Hasti Iranmanesh, Jonathon E. Beves, Anthony I. Day
Article
Chemistry, Medicinal
Shyam K. Konda, Ruqaya Maliki, Sean McGrath, Belinda S. Parker, Tina Robinson, Alex Spurling, Alison Cheong, Peter Lock, Paul J. Pigram, Don R. Phillips, Lynne Wallace, Anthony I. Day, J. Grant Collins, Suzanne M. Cutts
ACS MEDICINAL CHEMISTRY LETTERS
(2017)
Article
Chemistry, Analytical
Lubna R. Alrawashdeh, Michael P. Cronin, Anthony I. Day, Lynne Wallace, Clifford E. Woodward
Article
Chemistry, Multidisciplinary
Wenjing Wu, Michael P. Cronin, Lynne Wallace, Anthony I. Day
ISRAEL JOURNAL OF CHEMISTRY
(2018)
Article
Chemistry, Multidisciplinary
Biyun Sun, Ian F. Musgrave, Anthony I. Day, Kirsten Heimann, F. Richard Keene, J. Grant Collins
FRONTIERS IN CHEMISTRY
(2018)
Article
Chemistry, Organic
Pradeep Kumar Chandrakumar, Rajni Dhiman, Clifford E. Woodward, Hasti Iranmanesh, Jonathon E. Beves, Anthony I. Day
JOURNAL OF ORGANIC CHEMISTRY
(2019)
Article
Chemistry, Inorganic & Nuclear
K. M. Anis-Ul-Haque, Clifford E. Woodward, Anthony Day, Lynne Wallace
INORGANIC CHEMISTRY
(2020)
Article
Chemistry, Inorganic & Nuclear
Ena T. Luis, Anthony Day, Burkhard Koenig, Jonathon E. Beves
INORGANIC CHEMISTRY
(2020)
Article
Biochemistry & Molecular Biology
Minghua Chen, Naixia Lv, Weiwei Zhao, Anthony I. Day
Summary: The structural parameters of the cyclobutanoQ[5-8] family were determined by single crystal X-ray diffraction, revealing the importance of electropositive cyclobutano methylene protons in forming crystal packing arrangements. The electrostatic potential maps confirmed the electropositive nature of the cyclobutano CH2 and also showed that the cavities are electronegative, distinguishing them from classical Q[5-8] structures which are near neutral.
Article
Chemistry, Organic
Laode M. R. Al Muqarrabun, Asma S. Atthar, C. Pradeep Kumar, Vijaybabu Mandadapu, Ahmed Abdulrahman, Hasti Iranmanesh, Jonathon E. Beves, Anthony I. Day
Summary: Tetrahydrothiophenocucurbit[5]uril was chemically modified with thioether functionality and further transformed into the acetoxy derivative. In the presence of tetrahydrothiophenocucurbit[6]uril, nanoparticles of Au and Ag formed chains that grew in length over time.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Bayan Al Tbakhi, Hamdi Nsairat, Walhan Alshaer, Abdulfattah Al-Kadash, Wissam Helal, Lubna Alrawashdeh, Anthony Day, Khaleel I. Assaf, Rola Hassouneh, Fadwa Odeh, Abeer Al Bawab
Summary: This study investigates the physico-chemical properties and antitumor activity of cucurbit[7]uril and cinnamaldehyde inclusion complexes. The complexes are characterized for their stoichiometry, formation constant, particle size, and morphology. The study suggests potential 1:1 and 1:2 stoichiometries of the inclusion complexes, and their binding orientation. The complexes exhibit enhanced aqueous solubility and show antitumor activity against breast cancer and glioblastoma cell lines.
Review
Chemistry, Multidisciplinary
Rajni Dhiman, Satyavisal Pen, Pradeep Kumar Chandrakumar, Terry J. Frankcombe, Anthony I. Day
CHEMICAL COMMUNICATIONS
(2020)
