How aluminum adjuvants could promote and enhance non-target IgE synthesis in a genetically-vulnerable sub-population

Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome

(2014) M. Kool et al.   JOURNAL OF IMMUNOLOGY

A New Mechanism for Inhalational Priming: IL-4 Bypasses Innate Immune Signals

(2014) A. M. Dittrich et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Inflammasome Activation by Alum and Alum's Adjuvant Effect Are Mediated by NLRP3

(2014) H. Li et al.   JOURNAL OF IMMUNOLOGY

Analysis of NLRP3 in the Development of Allergic Airway Disease in Mice

(2012) I. C. Allen et al.   JOURNAL OF IMMUNOLOGY

Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent Mechanisms

(2011) Etsushi Kuroda et al.   IMMUNITY

Prostaglandin E2 enhances IL-33 production by dendritic cells

(2011) Yoshiki Yanagawa et al.   IMMUNOLOGY LETTERS

Thioredoxin and thioredoxin reductase: Current research with special reference to human disease

(2010) Arne Holmgren et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

The missing link: how the inflammasome senses oxidative stress

(2010) Chengcheng Jin et al.   IMMUNOLOGY AND CELL BIOLOGY

Regulatory T Cells Interfere with Glutathione Metabolism in Dendritic Cells and T Cells

(2010) Zhonghua Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The biological paths of IL-1 family members IL-18 and IL-33

(2010) Dirk E. Smith   JOURNAL OF LEUKOCYTE BIOLOGY

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

(2010) K. Schroder et al.   SCIENCE

Role of interleukin 33 in human immunopathology

(2009) G E J Murphy et al.   ANNALS OF THE RHEUMATIC DISEASES

Global safety of vaccines: strengthening systems for monitoring, management and the role of GACVS

(2009) Brigitte Autran et al.   Expert Review of Vaccines

Update on vaccination guidelines for allergic children

(2009) John M Kelso   Expert Review of Vaccines

IL-33–activated dendritic cells induce an atypical TH2-type response

(2009) Matthew A. Rank et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Selenium adsorption to aluminum-based water treatment residuals

(2009) James A. Ippolito et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Alum Induces Innate Immune Responses through Macrophage and Mast Cell Sensors, But These Sensors Are Not Required for Alum to Act As an Adjuvant for Specific Immunity

(2009) A. S. McKee et al.   JOURNAL OF IMMUNOLOGY

Extracellular redox modulation by regulatory T cells

(2009) Zhonghua Yan et al.   Nature Chemical Biology

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

(2009) Daniel F Gudbjartsson et al.   NATURE GENETICS

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

(2009) Rongbin Zhou et al.   NATURE IMMUNOLOGY

Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome

(2009) Fiona A. Sharp et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impairment of mitochondrial energy metabolism in different regions of rat brain following chronic exposure to aluminium

(2008) Vijay Kumar et al.   BRAIN RESEARCH

Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis

(2008) M. Sakashita et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity

(2008) Luigi Franchi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system

(2008) Y. Kondo et al.   INTERNATIONAL IMMUNOLOGY

IL-33 amplifies both Th1- and Th2-type responses through its activity on human basophils, allergen-reactive Th2 cells, iNKT and NK Cells

(2008) M. D. Smithgall et al.   INTERNATIONAL IMMUNOLOGY

Interleukin-18 enhances a Th2 biased response and susceptibility to Leishmania mexicana in BALB/c mice

(2008) Karen Jane Bryson et al.   MICROBES AND INFECTION

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE

The Nalp3 inflammasome is essential for the development of silicosis

(2008) Suzanne L. Cassel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Gender-specific effects of cytokine gene polymorphisms on childhood vaccine responses

(2008) Gareth Baynam et al.   VACCINE