Synthesis of Adipic Aldehyde by n-Selective Hydroformylation of 4-Pentenal

Several phosphine and phosphite ligands were tested in the hydroformylation of 4-pentenal to adipic aldehyde, a versatile starting material for industrially very relevant compounds. By varying the ligand structure we were able to increase the selectivity toward alipic aldehyde to >95%. Additionally, two molecular structures of important catalytic intermediates [(bisphosphite)RhH(CO)(2)] and one structure of a previously unknown catalyst decomposition product were obtained.