Palladium-Catalyzed Oxidative Heck-Type Alkylation/Aryl Migration/Desulfonylation between Alkenes with α-Carbonyl Alkyl Bromides

A new Pd(II)-catalyzed alkene oxidative difunctionalization initiated by Heck insertion has been developed for the selective synthesis of acyclic and cyclic all-carbon quaternary stereocenters, which achieves an oxidative Heck-type alkylation, aryl migration, and desulfonylation sequence and represents a different input from those previously used Heck coupling in synthesis is reported.