期刊
ORGANIC LETTERS
卷 17, 期 16, 页码 4046-4049出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b01969
关键词
-
资金
- Global R&D Center (GRDC) programs of the National Research Foundation of Korea (NRF) - Ministry of Science, ICT, and Future Planning of Korea (MSIFP) [NRF-2010-00719]
- Chungcheongbuk-do
- WCI
- KRIBB Research Initiative Program
Two novel cyclic depsipeptides, ulleungamides A (1) and B (2), were isolated from cultures of terrestrial Streptomyces sp. Their structures were determined by analyses of spectroscopic data and various chemical transformations, including modified Mosher's method, advanced Marfey's method, PGMF,, GITC derivatizations, and Snatzke's method. Ulleungamides were determined to be a new class of peptides bearing unprecedented units, such as 5-hydroxy-6-methyl-2,3-dehydropipecolic acid, 4,5-dihydroxy-6-methyl-2,3-dehydropipecolic acid, and amino-linked 2-isopropylsuccinic acid. Ulleungamide A displayed growth inhibitory activity against Staphylococcus aureus and Salmonella typhimurium without cytotoxicity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据