Article
Environmental Sciences
Shohreh F. Farzan, Caitlin G. Howe, Yu Chen, Diane Gilbert-Diamond, Susan Korrick, Brian P. Jackson, Adam R. Weinstein, Margaret R. Karagas
Summary: This study investigated the association between childhood exposure to mercury (Hg) and blood pressure measurements in young children, finding that exposure to Hg during childhood is linked to alterations in blood pressure, while early prenatal exposure to Hg is not related to changes in blood pressure.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Medicine, General & Internal
Hein Odendaal, Kimberly A. Dukes, Amy J. Elliott, Marian Willinger, Lisa M. Sullivan, Tara Tripp, Coen Groenewald, Michael M. Myers, William P. Fifer, Jyoti Angal, Theonia K. Boyd, Larry Burd, Jacob B. Cotton, Rebecca D. Folkerth, Gary Hankins, Robin L. Haynes, Howard J. Hoffman, Perri K. Jacobs, Julie Petersen, Nicolo Pini, Bradley B. Randall, Drucilla J. Roberts, Fay Robinson, Mary A. Sens, Peter Van Eerden, Colleen Wright, Ingrid A. Holm, Hannah C. Kinney
Summary: This cohort study found that dual exposure to drinking and smoking after the first trimester of pregnancy was associated with nearly 3 times the risk of late stillbirth compared with no exposure or quitting before the end of the first trimester, suggesting a significantly increased risk.
Review
Environmental Sciences
Airton C. Martins, Ana Carolina B. Almeida Lopes, Mariana R. Urbano, Maria de Fatima H. Carvalho, Ana Maria R. Silva, Alexey A. Tinkov, Michael Aschner, Arthur E. Mesas, Ellen K. Silbergeld, Monica M. B. Paoliello
Summary: The study reevaluated the relationship between cadmium exposure and altered blood pressure, finding a positive association between blood cadmium levels and blood pressure and/or hypertension. However, conflicting results and a lack of representative population-based studies of non-smokers leave uncertainty about the association between urinary cadmium and blood pressure and/or hypertension. Additional longitudinal studies are urgently needed to confirm the findings.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Peggy Hiu Ying Chan, Ka Ming Kwok, Michael Ho Ming Chan, Albert Martin Li, Iris Hiu Shuen Chan, Tai Fai Fok, Hugh Simon Lam
Summary: This study found an association between prenatal MeHg exposure and cardiac autonomic function in children, resulting in reduced parasympathetic activity. Adjustment for recent fish consumption further strengthened the negative associations of MeHg.
ENVIRONMENTAL RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Pierre-Antoine Dugue, Allison M. Hodge, Ee Ming Wong, JiHoon E. Joo, Chol-Hee Jung, John L. Hopper, Dallas R. English, Graham G. Giles, Roger L. Milne, Melissa C. Southey
Summary: The study revealed a strong positive association between DNA methylation marks of prenatal exposure to maternal smoking and increased risk of urothelial cancer. Potential negative associations were observed with risk of lung cancer and B-cell lymphoma. No associations were found for other cancers.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2021)
Article
Environmental Sciences
Haotian Wu, Allison Kupsco, Allan Just, Antonia M. Calafat, Emily Oken, Joseph M. Braun, Alison P. Sanders, Adriana Mercado-Garcia, Alejandra Cantoral, Ivan Pantic, Martha M. Tellez-Rojo, Robert O. Wright, Andrea A. Baccarelli, AndreaL. Deierlein
Summary: Phthalate exposure during pregnancy is associated with changes in maternal blood pressure trajectories postpartum, particularly with higher blood pressure during late pregnancy and long-term changes in blood pressure.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2021)
Article
Environmental Sciences
Hui Gao, Meng-long Geng, Juan Tong, Bao-lin Wang, Kun Huang, Yi Zhang, Hong Gan, Bei-bei Zhu, Peng Ding, Qu-nan Wang, Jian-qing Wang, Cheng Zhang, Peng Zhu, Fang-biao Tao
Summary: There is no consensus on the impact of prenatal phthalate exposure on blood pressure and glyco-lipids in children. This study analyzes the relationship between prenatal phthalate exposure and childhood cardiometabolic risk using the Ma'anshan Birth Cohort. The study finds both linear and non-linear associations between specific phthalate exposures and the cardiometabolic risk in children.
Article
Environmental Sciences
Yufan Ma, Chunmei Liang, Zihan Wang, Xing Wang, Liangliang Xie, Shuman Tao, Shuangqin Yan, Xiaoyan Wu, Zhaolian Wei, Juan Tong, Xingyong Tao, Fangbiao Tao
Summary: This study explored the relationship between prenatal exposure to metals and blood pressure in children aged 5-6 years. It found that exposure to arsenic and mercury during pregnancy was associated with altered blood pressure in children. Multiple metals had a significant positive joint effect on children's blood pressure, and there may be an interaction between arsenic and mercury. The third trimester was identified as an important window of opportunity to mitigate the effects of metal exposure on children's blood pressure and long-term health.
ENVIRONMENTAL RESEARCH
(2023)
Article
Psychology, Clinical
Bereket Duko, Gavin Pereira, Kim Betts, Robert J. Tait, John Newnham, Rosa Alati
Summary: The study found an association between maternal prenatal tobacco exposure and an increased risk of tobacco smoking in offspring, especially when exposed during the first trimester and both trimesters of pregnancy. There was insufficient statistical evidence for an association between paternal smoking during pregnancy and the risk of tobacco smoking in offspring.
ADDICTIVE BEHAVIORS
(2021)
Article
Environmental Sciences
Yaqian Wang, Susu Wang, Yihong Wang, Anxin Lu, Lulu Cao, Ju Wang, Zhenyan Gao, Chonghuai Yan
Summary: This study investigated the prenatal exposure to arsenic and its effects on birth size in Wujiang City, Jiangsu, China. The results showed that low-level prenatal exposure to arsenic could have negative effects on birth weight, especially among male infants.
Article
Environmental Sciences
Jingjia Liang, Cheng Xu, Qian Liu, Zhenkun Weng, Xin Zhang, Jin Xu, Aihua Gu
Summary: This study found a positive association between acrylamide exposure, particularly its metabolite, glycidamide, and the prevalence of hypertension or increased systolic blood pressure in adolescent females. Total cholesterol was found to mediate a portion of this association.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Multidisciplinary Sciences
Elisa Guma, Maude Bordeleau, Fernando Gonzalez Ibanez, Katherine Picard, Emily Snook, Gabriel Desrosiers-Gregoire, Shoshana Spring, Jason P. Lerch, Brian J. Nieman, Gabriel A. Devenyi, Marie-Eve Tremblay, M. Mallar Chakravarty
Summary: Exposure to maternal immune activation (MIA) during pregnancy affects embryo development, with early exposure leading to increased apoptotic cell density, and late exposure, especially in female embryos, resulting in increased neuroinflammation and oxidative stress.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Clinical Neurology
S. Jeremy Lum, M. Katrina Bird, Jennifer Wilkie, J. Samuel Millard, Sachie Pallimulla, A. Kelly Newell, M. Ian Wright
Summary: The research describes a clinically relevant rat model of MMT to assess the long-term behavioral and neurobiological effects of prenatal methadone exposure on adolescent offspring. The results showed that methadone-exposed offspring had significantly lower body and brain weights at birth, and exhibited cognitive impairments and working memory learning deficits during adolescence.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Article
Environmental Sciences
Hsiao-Lin Hwa, Fu-Shiang Peng, Te-Tien Ting, Huei-Wen Chen, Hsiang-Yu Chan, Da-Peng Yang, Pau-Chung Chen, Yun-Ning Kuo, Pai-Shan Chen
Summary: This study investigates the association between prenatal exposure to phthalates and birth outcomes in infants. The results suggest that certain phthalate metabolites are correlated with anogenital index and head circumference in male and female infants.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Priyanka D. Pinky, Mohammed Majrashi, Ayaka Fujihashi, Jenna Bloemer, Manoj Govindarajulu, Sindhu Ramesh, Miranda N. Reed, Timothy Moore, Vishnu Suppiramaniam, Muralikrishnan Dhanasekaran
Summary: Prenatal cannabinoid exposure can lead to long-lasting effects on the cerebellum, including altered oxidative stress markers, enhanced mitochondrial function, and changes in apoptotic protein levels. This exposure enhances neuronal survival and mitochondrial activity, providing unique effects on the cerebellum compared to other brain regions. Further research is needed to understand the mechanisms behind these alterations and their impact on behavior.
Review
Psychology, Developmental
Gabrielle Beaudry, Rongqin Yu, Niklas Langstrom, Seena Fazel
Summary: The study found high prevalence rates of various mental disorders in male and female adolescents in juvenile detention and correctional facilities, with higher rates of major depression and PTSD in female adolescents compared to males. Studies published after 2006 showed higher rates of ADHD and conduct disorder, indicating a potential increase in prevalence over time.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2021)
Article
Psychiatry
Christoph Abe, Roberth Adebahr, Benny Liberg, Christian Mannfolk, Alexander Lebedev, Jonna Eriksson, Niklas Langstrom, Christoffer Rahm
Summary: This study quantified neurobiological and clinical correlates of Pedophilic disorder (PD) by comparing PD patients with healthy controls, revealing psychiatric comorbidity, neurodevelopmental abnormalities, and cognitive correlates in PD individuals. These findings suggest that neurodevelopmental mechanisms are involved in PD and should be considered in the future clinical management of PD patients.
ACTA PSYCHIATRICA SCANDINAVICA
(2021)
Article
Allergy
Gustaf Rejno, Cecilia Lundholm, Sissel Saltvedt, Kjell Larsson, Catarina Almqvist
Summary: The study did not find evidence supporting an influence of maternal asthma on early fetal growth. The impact of asthma on fetal growth is likely to be very small, with no statistically significant differences observed between women with and without asthma in terms of reduced or increased growth.
CLINICAL AND EXPERIMENTAL ALLERGY
(2021)
Letter
Psychology, Developmental
Gabrielle Beaudry, Rongqin Yu, Niklas Langstrom, Seena Fazel
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2021)
Editorial Material
Multidisciplinary Sciences
Andrea Ganna, Karin J. H. Verweij, Michel G. Nivard, Robert Maier, Robbee Wedow, Alexander S. Busch, Abdel Abdellaoui, Shengru Guo, J. Fah Sathirapongsasuti, Paul Lichtenstein, Sebastian Lundstrom, Niklas Langstrom, Adam Auton, Kathleen Mullan Harris, Gary W. Beecham, Eden R. Martin, Alan R. Sanders, John R. B. Perry, Benjamin M. Neale, Brendan P. Zietsch
Summary: The complexity of human sexuality cannot be fully captured by a single variable, and genetic influences show substantial overlap between the variable and more nuanced measures of sexual behavior, attraction, and identity.
Article
Psychiatry
Martin Larden, Jens Hogstrom, Niklas Langstrom
Summary: The study found that individual cognitive behavioral therapy did not have an additional effect on residential psychological treatment for serious young male violent offenders. The limited sample size and high treatment dropout rates reduced the robustness of intent-to-treat effect estimates.
FRONTIERS IN PSYCHIATRY
(2021)
Correction
Psychology, Biological
Brendan P. Zietsch, Morgan J. Sidari, Abdel Abdellaoui, Robert Maier, Niklas Langstrom, Shengru Guo, Gary W. Beecham, Eden R. Martin, Alan R. Sanders, Karin J. H. Verweij
NATURE HUMAN BEHAVIOUR
(2021)
Article
Psychology, Biological
Brendan P. Zietsch, Morgan J. Sidari, Abdel Abdellaoui, Robert Maier, Niklas Langstrom, Shengru Guo, Gary W. Beecham, Eden R. Martin, Alan R. Sanders, Karin J. H. Verweij
Summary: This research finds that genetic effects associated with same-sex sexual behavior are associated with more sexual partners in individuals who only engage in opposite-sex sexual behavior. This could help explain the evolutionary maintenance of same-sex sexual behavior.
NATURE HUMAN BEHAVIOUR
(2021)
Review
Psychology, Clinical
Tina M. Olsson, Niklas Langstrom, Therese Skoog, Cecilia Andree Lofholm, Lina Leander, Agneta Brolund, Anna Ringborg, Pia Nykanen, Anneth Syversson, Knut Sundell
Summary: The study aimed to evaluate the effectiveness of noninstitutional psychosocial interventions in preventing recidivism among criminal adolescents but found that the interventions did not significantly reduce recidivism rates. While some individual studies suggested positive effects, the overall evidence had very low certainty.
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
(2021)
Article
Allergy
Emma Caffrey Osvald, Tong Gong, Cecilia Lundholm, Henrik Larsson, B. K. Brew, Catarina Almqvist
Summary: The study confirms an association between low parental SES (measured as education) and asthma/wheeze, with cousin comparison suggesting that this association is not solely due to confounding of unknown familial factors, supporting a causal relationship. However, the relationship between parental income and asthma/wheeze is less clear. The findings of this study are important for understanding risk factors for asthma/wheeze and for developing future prevention strategies. Further research is needed to investigate the possible mechanisms underlying the association between parental education and asthma/wheeze.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Allergy
Bronwyn K. Brew, Catarina Almqvist, Cecilia Lundholm, Anna Andreasson, Kelli Lehto, Nicholas J. Talley, Tong Gong
Summary: GERD is a common comorbidity in adults with asthma, hay fever, and/or eczema. There is evidence for shared mechanisms suggesting common underlying causes that may involve affective traits requiring further investigation.
CLINICAL AND EXPERIMENTAL ALLERGY
(2022)
Article
Multidisciplinary Sciences
Rongqin Yu, Niklas Langstrom, Mats Forsman, Arvid Sjolander, Seena Fazel, Yasmina Molero
Summary: This study examined the differences in recidivism rates between different prisons using both between-individual and within-individual designs. The results showed differences in recidivism risk between prisons in the between-individual analysis, but minimal differences in the within-individual analysis. The study highlights the importance of adjusting for individual-level confounding factors in research design.
Article
Criminology & Penology
Rongqin Yu, Yasmina Molero, Niklas Langstrom, Thomas Fanshawe, Denis Yukhnenko, Paul Lichtenstein, Henrik Larsson, Seena Fazel
Summary: A study was conducted on a national cohort of sexual offenders in Sweden, developing prediction models for three outcomes and validating their accuracy. The models for violent and any reoffending showed good discrimination and calibration, while the model for sexual reoffending had modest discrimination. The study also developed web-based risk calculators that are freely available.
JOURNAL OF CRIMINAL JUSTICE
(2022)
Article
Psychology, Clinical
Johanna Latth, Valdemar Landgren, Allison McMahan, Charlotte Sparre, Julia Eriksson, Kinda Malki, Elin Soderquist, Katarina Gorts Oberg, Alexander Rozental, Gerhard Andersson, Viktor Kaldo, Niklas Langstrom, Christoffer Rahm
Summary: This study investigated the effectiveness of Prevent It, a cognitive behavioral therapy, in reducing the viewing of child sexual abuse material (CSAM). The results showed that participants in the Prevent It group experienced a significant decrease in viewing time, with fewer side effects compared to the control group.
INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH
(2022)
Article
Criminology & Penology
Rebecca Siponen, Anneli Andersson, Sofi Oskarsson, Miguel Garcia-Argibay, Amber L. Beckley, Niklas Langstrom, Seena Fazel, Zheng Chang, Henrik Larsson, Brittany Evans, Catherine Tuvblad
Summary: By using Swedish population-based registers, the study found that imprisonment and potential childhood risk factors are closely associated with unintentional injury and premature death rates among youth offenders. Imprisoned youth offenders had the highest risk, followed by non-imprisoned youth offenders, compared to non-convicted youth. All childhood risk factors increased the risk for these outcomes among non-imprisoned youth offenders. Among imprisoned youth offenders, parental criminal convictions and psychiatric disorders increased the risk for unintentional injury, and parental and own childhood psychiatric disorders increased the risk for premature death.
JOURNAL OF CRIMINAL JUSTICE
(2023)