Fe-Catalyzed Direct α C-H Amination of Carbonyl Compounds

A direct Fe-catalyzed alpha-amination of 1,3-dicarbonyl compounds :has been accomplished using, arylhydroxylamines as aminating agents, This novel protocol allows convenient access to alpha-amino carbonyl derivatives without the need for any postreaction manipulations. This is an operationally simple procedure that works at low temperatures in shorter reaction times and produces high yields with excellent N-selectivity.