Synthesis of (Z)-(arylamino)-pyrazolyl/isoxazolyl-2-propenones as tubulin targeting anticancer agents and apoptotic inducers

Synthesis and Biological Evaluation of Imidazopyridine-Oxindole Conjugates as Microtubule-Targeting Agents

(2013) Ahmed Kamal et al.   ChemMedChem

Synthesis, biological evaluation and molecular docking studies of 3-(1,3-diphenyl-1H-pyrazol-4-yl)-N-phenylacrylamide derivatives as inhibitors of HDAC activity

(2012) Xi Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors

(2012) Ahmed Kamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

(Z)-1-Aryl-3-arylamino-2-propen-1-ones, Highly Active Stimulators of Tubulin Polymerization: Synthesis, Structure–Activity Relationship (SAR), Tubulin Polymerization, and Cell Growth Inhibition Studies

(2012) M. V. Ramana Reddy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antimitotic and Tubulin Interaction Profiles of Novel Pinacol Derivatives of Podophyllotoxins

(2012) Andrés Abad et al.   JOURNAL OF MEDICINAL CHEMISTRY

Polyalkoxybenzenes from Plants. 5. Parsley Seed Extract in Synthesis of Azapodophyllotoxins Featuring Strong Tubulin Destabilizing Activity in the Sea Urchin Embryo and Cell Culture Assays

(2011) Marina N. Semenova et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 7-Hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a Tubulin Polymerization Inhibitor with Potent Antiproliferative and Tumor Vascular Disrupting Properties

(2011) Bernard L. Flynn et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and tubulin-binding properties of new allocolchicinoids

(2010) François-Didier Boyer et al.   BIOORGANIC CHEMISTRY

Microwave-assisted synthesis and in-vitro anti-tumor activity of 1,3,4-triaryl-5-N-arylpyrazole-carboxamides

(2010) Hatem A. Abdel-Aziz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 3,5-diaryl isoxazoline/isoxazole linked 2,3-dihydroquinazolinone hybrids as anticancer agents

(2010) Ahmed Kamal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues

(2010) Romeo Romagnoli et al.   JOURNAL OF MEDICINAL CHEMISTRY

ELR510444, A Novel Microtubule Disruptor with Multiple Mechanisms of Action

(2010) A. L. Risinger et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Polymer prodrug approaches applied to paclitaxel

(2010) Jeong Sun Sohn et al.   Polymer Chemistry

Synthesis, structure and antibacterial activity of novel 1-(5-substituted-3-substituted-4,5-dihydropyrazol-1-yl)ethanone oxime ester derivatives

(2008) Xin-Hua Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Microtubule dynamics as a target in oncology

(2008) April L. Risinger et al.   CANCER TREATMENT REVIEWS

Synthesis and structure–activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung cancer cells

(2008) Yong Xia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New tubulin targeting agents currently in clinical development

(2008) Robert O Carlson   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Synthesis and antifungal activity of some new 3-hydroxy-2-(1-phenyl-3-aryl-4-pyrazolyl) chromones

(2007) Om Prakash et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY