4.6 Article

Regioselective synthesis of 2H-indazoles through Ga/Al- and Al-mediated direct alkylation reactions of indazoles

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ORGANIC & BIOMOLECULAR CHEMISTRY
卷 13, 期 46, 页码 11376-11381

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob01747e

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  1. Ministry of Science and Technology of the Republic of China, Taiwan [MOST 104-2113-M-018-005]

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A procedure has been developed for the regioselective, high yielding synthesis of 2H-indazoles that involves direct alkylation of indazoles with various allyl and benzyl bromides, and alpha-bromocarbonyl compounds.

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