Clinical challenge of hyponatremia in heart failure

Hyponatremia is a significant and independent predictor of outcomes including rehospitalization and mortality in patients with both acute decompensated heart failure (HF) and chronic HF. Even modest degrees of hyponatremia are associated with a poorer prognosis. Treatment options include fluid restriction and the vaptan class (aquaretics) in select patients. Journal of Hospital Medicine 2012; 7:S6S10. (c) 2012 Society of Hospital Medicine