期刊
JOURNAL OF HOSPITAL INFECTION
卷 101, 期 2, 页码 167-174出版社
W B SAUNDERS CO LTD
DOI: 10.1016/j.jhin.2018.09.010
关键词
Antimicrobial resistance; Vertical transmission; Risk factors
资金
- Plan Nacional de I+D+i 2013-2016
- Instituto de Salud Carlos III, Subdireccion General de Redes y Centros de Investigacion Cooperativa, Ministerio de Economia, Industria y Competitividad through Spanish Network for Research in Infectious Diseases [REIPI RD12/0015/0010, REIPI RD16/0016/0001]
- European Development Regional Fund 'A way to achieve Europe', Operative Programme Intelligent Growth 2014-2020
- Instituto de Salud Carlos III, Subdireccion General de Redes y Centros de Investigacion Cooperativa, Ministerio de Economia, Industria y Competitividad through AES 2016 [AC16/00076]
- JPI-EC-AMR framework (MODERN)
This study sought to determine the prevalence and risk factors for colonization with extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) and carbapenemase-producing Enterobacteriaceae (CPE) in 815 mothers and 800 newborns using a cross-sectional design; 59 women and 13 neonates were colonized by ESBL-E (prevalence (95% confidence interval): 6.7% (5.2-8.7) and 1.6 (0.7-2.5), respectively). No CPE were found. The most frequent ESBL-E were CTX-M-14 and SHV-12. Vertical transmission occurred in 14% of colonized mothers. The risk factors for colonization were, in mothers: complications in previous pregnancies, more than one urinary tract infection, non-Caucasian ethnicity, and frequently having the main meal outside home; in newborns: colonized mother and vaginal delivery. (C) 2018 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
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