期刊
JOURNAL OF HOSPITAL INFECTION
卷 87, 期 3, 页码 145-151出版社
W B SAUNDERS CO LTD
DOI: 10.1016/j.jhin.2014.04.003
关键词
Community-associated infection; Disease outbreak; Meticillin-resistant; Staphylococcus aureus; Newborn; Pantone-Valentine leucocidin
资金
- PHS HHS [HHSN272200700055C] Funding Source: Medline
Background: The prevalence of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) is increasing throughout the world and is an important cause of skin and soft tissue infection (SSTI) in children and neonates. Aim: To describe the successful control of an outbreak caused by a new strain of CA-MRSA in a newborn nursery. Methods: The investigation of the outbreak in July 2012 is reported with the control measures taken. Molecular typing of the MRSA isolates was performed. Findings: An outbreak of SSTI caused by CA-MRSA occurred in a newborn nursery. Six neonates were infected in a one-month period [infection rate: 8.5% (6/71)]. Anew variant of CA-MRSA was responsible, which was characterized as USA300-related, Pantone-Valentine Leucocidin (PVL) positive, arginine catabolic mobile element (ACME) negative, sequence type 8 (ST8), staphylococcal cassette chromosome mec (SCCmec) type IVa, agr type I and spa type t008. The outbreak among term neonates followed a rapid transmission pattern and was successfully controlled by implementing various outbreak control measures, including universal chlorhexidine bathing. Conclusion: This is the first report of a hospital outbreak caused by a USA300-related CA-MRSA clone in Korea. Early recognition and reinforcement of infection control measures are important in decreasing transmission of CA-MRSA in a hospital setting. (C) 2014 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据