Article
Medicine, General & Internal
Veronica Romano, Donato Di Gennaro, Anna Maria Sacco, Enrico Festa, Emanuela Roscetto, Morena Anna Basso, Tiziana Ascione, Giovanni Balato
Summary: This study evaluated the cytotoxicity of solutions containing povidone-iodine (PI) and hydrogen peroxide (H2O2), alone or in combination. The results showed that the toxicity of all tested solutions increased as exposure time increased, except for 0.3% PI solution, which exhibited the lowest toxicity. The combined solutions had lower cellular killing at 3 and 5 min compared to equal concentrations of H2O2, similar to PI solutions.
Article
Biochemistry & Molecular Biology
Anna-Lena Severing, Mia Borkovic, Ewa K. Stuermer, Julian-Dario Rembe
Summary: The study found that current standard methods do not fully consider the impact of wound microenvironments on the efficacy of antimicrobial agents, and there are also differences in the antimicrobial effects against different bacteria. The composition of the challenge substance is more important than pure concentration.
Article
Ophthalmology
Smriti Nair, Aretha Zhu, Mustafa Jaffry, Hassaam Choudhry, Mohammad H. H. Dastjerdi
Summary: This paper aims to compile information on the use, safety profile, adverse effects, and possible alternatives of Povidone-iodine (PVI). While the allergic potential to PVI is disputed, there are nonallergic adverse effects of PVI that should not be overlooked. Alternatives to PVI including chlorhexidine, polyhexamethylene biguanide, and octenidine have been identified.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
(2023)
Review
Pharmacology & Pharmacy
Alina Chelmus-Burlacu, Lenuta Profire, Dragos Pieptu
Summary: This paper evaluates recent published data on the effectiveness of povidone-iodine as a wound care option and its impact on wound healing. The results show that povidone-iodine has similar antimicrobial efficacy but controversial effects on wound healing. Recent data focuses on comparing different antiseptics and proposing algorithms for wound management. However, the heterogeneity in experimental designs emphasizes the importance of standardized antimicrobial tests and clinical guidelines.
Article
Allergy
Susann Forkel, Caroline Beutner, Katharina Amschler, Silke Sabina Schroeder, Michael P. Schoen, Johannes Geier, Timo Buhl
Summary: Patch testing with PVP-I 2% aq. showed the lowest number of doubtful skin reactions while detecting the single allergic patient, suggesting it as the optimal preparation for iodine patch tests. Overestimation of iodine allergy was indicated, and positive patch test responses to iodine should be confirmed with ROATs before diagnosis.
CONTACT DERMATITIS
(2021)
Article
Polymer Science
Danelya N. Makhayeva, Galiya S. Irmukhametova, Vitaliy V. Khutoryanskiy
Summary: This review focuses on the ability of iodine to form complexes with water-soluble polymers and other molecules, and its remarkable antimicrobial properties against various pathogens. It covers historical information on iodine and iodophors, existing iodine-containing products available in the market, physicochemical methods employed to study polymer-iodine complexes, and recent studies on iodophors.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Microbiology
Justyna Paleczny, Adam Junka, Malwina Brozyna, Karolina Dydak, Monika Oleksy-Wawrzyniak, Daria Ciecholewska-Jusko, Ewelina Dziedzic, Marzenna Bartoszewicz
Summary: This study demonstrates how changing a single variable (medium composition) in the standard in vitro model not only affects the characteristics of staphylococcal biofilms, but also may alter the efficacy of clinically applied wound antimicrobials.
Article
Chemistry, Physical
Farhana Parvin, Karen Vickery, Anand K. Deva, Honghua Hu
Summary: This study evaluated the antibacterial and antibiofilm efficacy of four commercial surgical washes against six bacterial species commonly associated with surgical site infections and chronic wound infections. The results showed variations in the efficacy of the surgical washes against different bacterial species, emphasizing the importance of testing against various bacterial species for a comprehensive understanding of their efficacy.
Article
Engineering, Biomedical
Yanan Tang, Zhen Qin, Yinghui Zhong, Xianqiang Yan, Liang Kong, Xiangyu Yang, Shengyan Yin, Mo Li, Zhenning Liu, Hang Sun
Summary: In this study, a Nepenthes-inspired nanosheet array of MoS2 on carbon fibers (CF-MoS2) is developed for dual bactericidal activities. The material can physically disrupt cell membranes and induce bacterial death through photothermal effects. In vivo experiments demonstrate the material's potential for synergistic disinfection and promotion of wound regeneration.
ADVANCED HEALTHCARE MATERIALS
(2022)
Review
Biochemistry & Molecular Biology
Miriam Ting, Alex Dahlkemper, Jeremy J. Schwartz, Manzel Woodfork, Jon B. Suzuki
Summary: This systematic review evaluated the efficacy of antiseptic mouth rinses as a preprocedural rinse in reducing SARS-CoV-2 oral viral load. The study found that preprocedural mouth rinses can significantly reduce SARS-CoV-2 in the mouth, thereby reducing airborne viral dispersion. Therefore, preprocedural mouth rinses may be an effective strategy to reduce the spread of COVID-19 in selected medical and healthcare facilities, including dental clinics.
Article
Microbiology
Tetyana Valeriyivna Denysko, Oleksandr Adamovych Nazarchuk, Oleksandr Gruzevskyi, Nataliia Anatoliivna Bahniuk, Dmytro Valeriiovych Dmytriiev, Roman Mykolayovych Chornopyschuk, Vira Volodymyrivna Bebyk
Summary: In the context of increasing antibiotic resistance, antiseptics play a crucial role in preventing opportunistic infections. This study demonstrates the effectiveness of modern antiseptics in treating wound infections caused by multidrug-resistant Acinetobacter baumannii, a high-priority wound pathogen. The results show that antiseptics such as chlorhexidine and decamethoxine have potent bactericidal activity and can inhibit biofilm formation by A. baumannii.
FRONTIERS IN MICROBIOLOGY
(2022)
Review
Public, Environmental & Occupational Health
Jianhua Wei, Lingying He, Fengxia Weng, Fangfang Huang, Peng Teng
Summary: In patients undergoing cardiac surgery, chlorhexidine (CHX) does not protect against surgical site infection (SSI), deep wound infection, and urinary tract infections, but may protect against superficial SSI, bloodstream infection, nosocomial infections, and pneumonia.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2021)
Review
Dermatology
Kevin Woo, Caroline Dowsett, Ben Costa, Stephen Ebohon, Emma J. Woodmansey, Matthew Malone
Summary: The study summarizes the clinical effectiveness of cadexomer iodine in the treatment of chronic wounds, promoting wound bed preparation and healing process by removing barriers to healing.
INTERNATIONAL WOUND JOURNAL
(2021)
Article
Infectious Diseases
Koko Barrigah-Benissan, Jerome Ory, Albert Sotto, Florian Salipante, Jean-Philippe Lavigne, Paul Loubet
Summary: The study found that the use of iodine antiseptic agents in chronic wound care can promote wound healing and has a better effect compared to saline. However, there is not enough evidence to suggest a significant difference in wound healing with octenidine or polyhexanide. No adverse events were found to be influenced by any antiseptic agents compared to saline during the study.
Article
Microbiology
Ewa Klara Stuermer, Isabell Plattfaut, Michael Dietrich, Florian Brill, Andreas Kampe, Vanessa Wiencke, Anna Ulatowski, Maria Geffken, Julian-Dario Rembe, Ella Alexandrovna Naumova, Sebastian Eike Debus, Ralf Smeets
Summary: The study focused on the efficacy of antimicrobial dressings for wounds with biofilms, with cadexomer-iodine (C-IOD) showing the best bacterial reduction while octendine di-hydrochloride (OCT) and ionic silver (AG) dressings did not meet expectations. Chemical interaction with biofilm extrapolymeric substance (EPS) and dressing configuration are suggested to be responsible for the diverse results, indicating a need to rethink non-debridement anti-biofilm therapy.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Haske van Veenendaal, Helene R. Voogdt-Pruis, Dirk T. Ubbink, Esther van Weele, Lejla Koco, Maaike Schuurman, Jannie Oskam, Ella Visserman, Carina G. J. M. Hilders
Summary: The evaluation of a multilevel implementation program on shared decision making (SDM) for breast cancer clinicians showed that the program supported clinicians to adopt SDM and helped internalize the SDM theory. Common barriers reported by clinicians included limited financial means, time constraints, and concurrent activities.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Cardiac & Cardiovascular Systems
Yvonne Koop, Nikita van Zadelhof, Angela H. E. M. Maas, Femke Atsma, Saloua El Messaoudi, Hester Vermeulen
Summary: CTRCD has a negative impact on the QoL of BC patients, affecting their physical, social, and psychosocial well-being. Healthcare experiences are influenced by a lack of acknowledgement and professional communication, and patients emphasize the need for personalized care.
EUROPEAN JOURNAL OF CARDIOVASCULAR NURSING
(2022)
Article
Surgery
A. C. M. Geraedts, S. Mulay, C. B. Terwee, A. C. Vahl, H. J. M. Verhagen, C. Unlu, D. T. Ubbink, M. J. W. Koelemay, R. Balm
Summary: This study investigated the anxiety levels of patients after endovascular aortic aneurysm repair (EVAR) before receiving imaging surveillance results and compared them with the general 65+ Dutch population. The results showed that patients did not experience a significant increase in anxiety levels just before receiving the imaging results compared to standard anxiety levels. However, compared to the general 65+ Dutch population, patients experienced more anxiety and worse physical outcomes.
ANNALS OF VASCULAR SURGERY
(2022)
Article
Oncology
Yvonne Koop, Arco J. Teske, Iris Wanders, Hanneke Meijer, J. H. A. M. (Hans) Kaanders, Olivier C. Manintveld, H. Carlijne Hassing, Hester Vermeulen, Angela H. E. M. Maas, Dick-Johan van Spronsen, Femke Atsma, Saloua El Messaoudi
Summary: This study evaluated current perspectives on cardio-oncology and found that professionals have limited awareness and knowledge of cardio-oncology guidelines, leading to insufficient treatment for cardio-oncology patients. There is a strong need for additional training and practical guidelines in this field.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Geriatrics & Gerontology
Inge A. H. Knippenberg, Ruslan Leontjevas, Slavi Stoyanov, Anke Persoon, Peter Verboon, Hester Vermeulen, Jacques J. D. M. van Lankveld, Debby L. Gerritsen
Summary: The study aims to identify and structure potential informal antidepressant strategies for nursing home residents to use in daily practice alongside formal treatments. Through two Group Concept Mapping studies, researchers identified multiple strategies that residents and others could use and evaluated their expected effectiveness and feasibility. The results emphasize the importance of social connectedness, personalized attention, and adaptations to the physical environment in preventing and alleviating depression.
AGING & MENTAL HEALTH
(2023)
Article
Surgery
Fabienne E. Stubenrouch, Loes J. Peters, Sylvana M. L. de Mik, Peter L. Klemm, Arnoud G. Peppelenbosch, Stella C. W. M. Schreurs, Dick M. Scharn, Dink A. Legemate, Ron Balm, Dirk T. Ubbink
Summary: Introduction of decision support tools improves the level of shared decision making in vascular surgery, increases patient knowledge, and shifts their preference towards more non-surgical treatments.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2022)
Article
Orthopedics
Roel van Oorsouw, Anke Oerlemans, Emily Klooster, Manon van den Berg, Johanna Kalf, Hester Vermeulen, Maud Graff, Philip van den Wees, Niek Koenders
Summary: This study explored the lived experiences of rehabilitation professionals working in hospitals during the COVID-19 pandemic, highlighting ethical issues and moral distress they encountered. The findings showed a significant impact on the working environment, while also revealing moments of freedom and solidarity among participants.
Article
Surgery
Alexandra H. J. Janssen, Andrea W. van Bruggen-van der Lugt, Johannes A. Wegdam, Tammo S. de Vries Reilingh, Susan van Dieren, Hester Vermeulen, Anne M. Eskes
Summary: This study aimed to assess the predictive value of prognostic determinants to nonadherence to negative pressure wound therapy. The results showed that patients with sensitive skin may have an increased risk of premature termination of negative pressure wound therapy. Further research is needed to determine strategies to overcome skin irritation problems and prevent nonadherence.
Article
Education, Scientific Disciplines
Iris Jansen, Milou E. W. M. Silkens, Gerbrich Galema, Hester Vermeulen, Suzanne E. Geerlings, Kiki M. J. M. H. Lombarts, Renee E. Stalmeijer
Summary: This study aimed to understand the guiding role of nurses in residents' workplace learning and explore the perceptions and reasons of residents and nurses regarding this role. The results showed that nurses provided more support and guidance in learning from patient care compared to the perceptions of residents. Additionally, nurses indicated that attending physicians did not always involve them in guiding residents, while residents perceived nurses to be involved.
Review
Surgery
Matthew Machin, Isabelle Van Herzeele, Dirk Ubbink, Janet T. Powell
Summary: The study aimed to summarize the current knowledge of shared decision making (SDM) in patients with intact abdominal aortic aneurysms (AAA) and identify areas where further evidence is needed. The results showed that most patients with AAA desire SDM, but it is not commonly practiced. Patients with AAA do not receive adequate information for SDM, although the use of tailored decision support tools (DSTs) can improve patient knowledge and facilitate SDM.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Article
Nursing
Gerda Van Den Berg, Hester Vermeulen, Tiffany Conroy, Harm Van Noort, Marian De Van Der Schueren, Getty Huisman-de Waal
Summary: This study explores nursing nutritional care delivery in hospitals through observations of nursing care and discussions with multidisciplinary professionals. It highlights the crucial role of nurses in identifying and treating malnutrition and emphasizes the importance of a systematic nursing approach combined with patient participation to counteract malnutrition effectively.
JOURNAL OF CLINICAL NURSING
(2023)
Letter
Dermatology
A. M. van Huizen, N. J. Rietbergen, G. E. van der Kraaij, D. T. Ubbink, Ph. I. Spuls
JOURNAL OF DERMATOLOGICAL TREATMENT
(2023)
Letter
Surgery
D. T. Ubbink
BRITISH JOURNAL OF SURGERY
(2023)
Article
Oncology
Haske van Veenendaal, Loes J. Peters, Esther van Weele, Mathijs P. Hendriks, Maaike Schuurman, Ella Visserman, Carina G. J. M. Hilders, Dirk T. Ubbink
Summary: This study investigated the effect of a multilevel shared decision-making (SDM) implementation program in breast cancer care. The results showed that the program led to a significant improvement in the application of SDM by clinicians, especially in discussing options. However, patients' perceived level of SDM did not change, even after the implementation of the program. Exposure to the program, redistribution of tasks, and discussing feedback from consultations were associated with a higher level of SDM.
Article
Psychiatry
Thea H. Daggenvoorde, Miranda van Eerden, Silvio C. G. H. van den Heuvel, Harm J. Gijsman, Hester Vermeulen, Peter J. J. Goossens
Summary: The study found that collaboration between police officers and MCT members in responding to emergencies involving 'persons with confused behavior' is challenging due to different perspectives and expectations leading to friction and stagnation. Police prefer prompt involvement of MCT, while MCT aims to provide accessible and problem-identifying services for police.
INTERNATIONAL JOURNAL OF SOCIAL PSYCHIATRY
(2022)
