A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma

Differential MyD88/IRAK4 requirements for cross-priming and tumor rejection induced by heat shock protein 70-model antigen fusion protein

(2012) Shusaku Mizukami et al.   CANCER SCIENCE

Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy

(2012) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCL12/CXCR4 Blockade Induces Multimodal Antitumor Effects That Prolong Survival in an Immunocompetent Mouse Model of Ovarian Cancer

(2011) E. Righi et al.   CANCER RESEARCH

Cancer Immunotherapy Comes of Age

(2011) Suzanne L. Topalian et al.   JOURNAL OF CLINICAL ONCOLOGY

Redirected Antitumor Activity of Primary Human Lymphocytes Transduced With a Fully Human Anti-mesothelin Chimeric Receptor

(2011) Evripidis Lanitis et al.   MOLECULAR THERAPY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Listening to Provenge — What a Costly Cancer Treatment Says about Future Medicare Policy

(2011) James D. Chambers et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vaccination with B16 Tumor Cell Lysate Plus Recombinant Mycobacterium tuberculosis Hsp70 Induces Antimelanoma Effect in Mice

(2010) He Li et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Building on dendritic cell subsets to improve cancer vaccines

(2010) Karolina Palucka et al.   CURRENT OPINION IN IMMUNOLOGY

A novel vaccine strategy to induce mycobacterial antigen-specific Th1 responses by utilizing the C-terminal domain of heat shock protein 70

(2010) Tomohiro Uto et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD8+ T Cell Priming by Dendritic Cell Vaccines Requires Antigen Transfer to Endogenous Antigen Presenting Cells

(2010) Alice W. Yewdall et al.   PLoS One

Mature dendritic cells use endocytic receptors to capture and present antigens

(2010) C. D. Platt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Human Cancer Antigen Mesothelin Is More Efficiently Presented to the Mouse Immune System when Targeted to the DEC-205/CD205 Receptor on Dendritic Cells

(2009) Bei Wang et al.   Annals of the New York Academy of Sciences

Effect of Recombinant Heat Shock Protein 70 of Mycobacterial Origin on Cytotoxic Activity and Immunophenotype of Human Peripheral Blood Mononuclear Leukocytes

(2009) D. S. Vorobiev et al.   BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE

Phase I Trial of Continuous Infusion Anti-Mesothelin Recombinant Immunotoxin SS1P

(2009) R. J. Kreitman et al.   CLINICAL CANCER RESEARCH

Mycobacterial HSP70 as an adjuvant in the design of an idiotype vaccine against a murine lymphoma

(2008) Lavakumar Karyampudi et al.   CELLULAR IMMUNOLOGY

Use of Yeast-Secreted In vivo Biotinylated Recombinant Antibodies (Biobodies) in Bead-Based ELISA

(2008) N. Scholler et al.   CLINICAL CANCER RESEARCH

Cancer Immunotherapy by Dendritic Cells

(2008) Cornelis J.M. Melief   IMMUNITY

Calcium Signaling in Dendritic Cells by Human or Mycobacterial Hsp70 Is Caused by Contamination and Is Not Required for Hsp70-mediated Enhancement of Cross-presentation

(2008) Henriette Bendz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enhanced T-Cell Responses to Glioma Cells Coated With the Anti-EGF Receptor Antibody and Targeted to Activating Fc??Rs on Human Dendritic Cells

(2008) Devi Banerjee et al.   JOURNAL OF IMMUNOTHERAPY