Review
Neurosciences
Rina Berman, Haley Spencer, Martin Boese, Sharon Kim, Kennett Radford, Kwang Choi
Summary: Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain injury (TBI) remains an ongoing research pursuit. This review summarizes the current knowledge on the associations between duration of loss of consciousness (LOC) and outcomes after mild TBI (mTBI) in humans and between loss of righting reflex (LRR) and outcomes after experimental TBI in rodents. Both LOC and LRR are associated with adverse outcome measures and can be useful in developing personalized treatment strategies.
Article
Behavioral Sciences
William H. Curley, Yelena G. Bodien, David W. Zhou, Mary M. Conte, Andrea S. Foulkes, Joseph T. Giacino, Jonathan D. Victor, Nicholas D. Schiff, Brian L. Edlow
Summary: This study demonstrates the use of the ABCD framework to assess EEG dynamics and track changes in thalamocortical network function in patients with acute severe traumatic brain injury. The findings suggest that ABCD classifications can provide valuable information for monitoring recovery and predicting outcomes.
Review
Biochemistry & Molecular Biology
William Torregrossa, Michele Torrisi, Rosaria De Luca, Carmela Casella, Carmela Rifici, Mirjam Bonanno, Rocco Salvatore Calabro
Summary: Traumatic brain injury is damage to the brain occurring after birth, resulting in deterioration of cognitive, behavioural, and emotional functions. Neuropsychological evaluation can assist clinicians in assessing the patient's condition, reaching differential diagnoses, and developing intervention strategies. However, it is difficult to determine the most suitable assessment tool for different brain injury conditions considering the various rating scales available.
Article
Neurosciences
Joel Frohlich, Julia S. Crone, Micah A. Johnson, Evan S. Lutkenhoff, Norman M. Spivak, John Dell'Italia, Joerg F. Hipp, Vikesh Shrestha, Jesus E. Ruiz Tejeda, Courtney Real, Paul M. Vespa, Martin M. Monti
Summary: This study confirms the validity of the ABCD model in predicting behavioral recovery in patients with moderate-to-severe traumatic brain injury. It outperforms data-driven clustering methods and may be equally effective as a more simplified categorization. Additionally, a correlation between EEG findings and functional magnetic resonance imaging provides further evidence for investigation in larger studies.
HUMAN BRAIN MAPPING
(2022)
Article
Clinical Neurology
Lena Ruehl, Joji B. Kuramatsu, Jochen A. Sembill, Bernd Kallmuenzer, Dominik Madzar, Stefan T. Gerner, Antje Giede-Jeppe, Stefanie Balk, Tamara Mueller, Jakob Jaeger, Stefan Schwab, Hagen B. Huttner, Maximilian Spruegel
Summary: This study found that amantadine treatment can improve consciousness in patients with non-traumatic brain injury. However, there may be an increased risk of epileptic seizures after treatment initiation. Further randomized controlled trials are needed to confirm these findings.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2022)
Article
Otorhinolaryngology
Elliott D. Kozin, Renata M. Knoll, Neil Bhattacharyya
Summary: There is a significant association between TBI and hearing loss in children, with those having TBI being 2.67 times more likely to have concurrent hearing complaints.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Review
Clinical Neurology
Altaf Saadi, Jasmin Williams, Ameerah Parvez, Margarita Alegria, Ana-Maria M. Vranceanu
Summary: The aim of this study was to assess the global prevalence of head trauma in refugees and asylum seekers and describe its clinical characteristics. The results showed a wide range of prevalence rates of head trauma in this population, and there is a lack of systematic screening approaches. Therefore, there is a need to increase attention to head trauma in displaced populations and provide equitable care.
Review
Rehabilitation
Harriet Ng, Andrew King
Summary: This systematic review examined the impact of head-up tilt on consciousness among individuals with prolonged disorders of consciousness. Findings suggest that passive standing on a tilt-table may have a positive effect on consciousness improvement, with medium to large effect sizes observed in some studies. However, the overall quality of the relevant studies is low and further research is required to explore this topic.
CLINICAL REHABILITATION
(2021)
Article
Clinical Neurology
Laura M. Franke, Robert A. Perera, Scott R. Sponheim
Summary: This study found that long-term changes in EEG spectra after mild traumatic brain injury (mTBI) are associated with injury characteristics and cognitive difficulties. However, there is no lasting effect of a history of mTBI or blast exposures on resting EEG measures of brain function.
FRONTIERS IN NEUROLOGY
(2023)
Article
Materials Science, Multidisciplinary
Yang Wan, Wenqiang Fang, Rika Wright Carlsen, Haneesh Kesari
Summary: Rotational head motions play a crucial role in traumatic brain injury, and there is a need for methods to quickly predict brain tissue strains and strain rates to estimate injury risk and guide protective equipment design. Idealized continuum mechanics based head models provide a simpler and faster approach to estimate brain strains and strain rates. In this study, a new head model accounting for finite rotations is proposed, which shows comparable strain predictions to a more detailed finite element head model. This model can serve as a basis for introducing finite rotations into more sophisticated head models in the future.
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2023)
Article
Surgery
Brett M. Tracy, Michael E. Silverman, Carlos Cordero-Caballero, Emily A. Durr, Rondi B. Gelbard
Summary: This retrospective study of 76 acutely hospitalized patients with severe TBI found that dual therapy with amantadine + methylphenidate was associated with better neurorecovery compared to monotherapy with amantadine.
JOURNAL OF SURGICAL RESEARCH
(2021)
Review
Biochemistry & Molecular Biology
Rosanna Squitti, Giuseppe Reale, Vincenzo Tondolo, Daniela Crescenti, Sonia Bellini, Marco Moci, Pietro Caliandro, Luca Padua, Mauro Rongioletti
Summary: Dysfunction of cerebral networks due to traumatic brain injury alters essential metals in the brain and may contribute to disorders of consciousness. Neuronal molecular mechanisms involving iron, zinc, and copper are affected, leading to neurodegeneration, synaptic dysfunction, and inflammation. Existing treatments for disorders of consciousness have an impact on essential metals-related pathways, and zinc shows promise as a potential therapeutic approach. Further research is needed to understand the role of metals in disorders of consciousness and explore metal-based drugs as potential treatments.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Pediatrics
Stephen C. Boos, Ming Wang, Wouter A. Karst, Kent P. Hymel
Summary: Using mathematical algorithms, this study aimed to classify young patients with acute head injury into subpopulations based on clinical and radiologic variables. The results showed that the algorithmic partition was predictive of physician diagnosis and replicated clinical differences between abusive head trauma (AHT) and non-AHT. These findings suggest the potential usefulness of mathematical algorithms in guiding AHT diagnosis.
Article
Clinical Neurology
Laura Josephine Hendrikx, Dominic Murphy
Summary: This study investigated the association between reported traumatic brain injury plus loss of consciousness (TBI + LOC) and a range of factors among UK veterans, revealing links with adverse childhood experiences, drug use, job loss, and physical health issues. These findings could be beneficial in enhancing the assessment and rehabilitation of veterans with TBI + LOC.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2021)
Article
Neurosciences
John Servider, Jordan R. Saadon, Joseph Adachi, Erica Shen, Charles B. Mikell, Sima Mofakham
Summary: This study investigates cortical electrophysiological recordings from a single TBI patient and finds that high-frequency activity associated with the return of consciousness reappears in a spatiotemporal fashion, potentially originating in more internal cortices and progressing to superficial ones.
Article
Psychiatry
K. E. Miller, A. Rasmussen
EPIDEMIOLOGY AND PSYCHIATRIC SCIENCES
(2017)
Article
Psychiatry
Andrew Rasmussen, Peter Ventevogel, Amelia Sancilio, Mark Eggerman, Catherine Panter-Brick
Review
Public, Environmental & Occupational Health
Brandon A. Kohrt, Andrew Rasmussen, Bonnie N. Kaiser, Emily E. Haroz, Sujen M. Maharjan, Byamah B. Mutamba, Joop T. V. M. de Jong, Devon E. Hinton
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2014)
Review
Public, Environmental & Occupational Health
Andrew Rasmussen, Eva Keatley, Amy Joscelyne
SOCIAL SCIENCE & MEDICINE
(2014)
Article
Psychology, Clinical
Andrew Rasmussen, Michelle Leon, Ask Elklit
Summary: This study found that comparing the severity of posttraumatic stress disorder (PTSD) symptoms using the Harvard Trauma Questionnaire (HTQ) across different adolescent samples from different countries may not be valid. Cultural similarity seems to influence measurement invariance.
Article
Psychology, Clinical
Sara A. Romero, Ye Feng, Priscilla Morales, Andrew Rasmussen
Summary: This study aims to explain the disparate prevalence of PTSD in the United States and Mexico. The results show that different social comparison effect types are associated with patients' perception of coping with trauma difficulty. Additionally, sociodemographic characteristics and the degree of trauma exposure are also associated with PTSD.
PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY
(2022)
Article
Psychology, Clinical
Obianujunwa Anakwenze, Andrew Rasmussen
Summary: The study found that parenting difficulty partially mediated the relationship between posttraumatic stress and child externalizing behavior. This relationship was not significant for parents separated from their children for one year or less, but was significant for those never separated or separated for longer than 1 year. Higher posttraumatic stress scores were most strongly associated with higher child externalizing behavior scores for those separated longer than one year.
PSYCHOLOGICAL TRAUMA-THEORY RESEARCH PRACTICE AND POLICY
(2021)
Article
Psychology, Clinical
Andrew Rasmussen, Jay Verkuilen, Nuwan Jayawickreme, Zebing Wu, Sydne T. McCluskey
CLINICAL PSYCHOLOGICAL SCIENCE
(2019)
Article
Criminology & Penology
Sumithra S. Raghavan, Barry Rosenfeld, Andrew Rasmussen
JOURNAL OF INTERPERSONAL VIOLENCE
(2017)
Article
Psychology, Multidisciplinary
Maarten De Schryver, Sofie Vindevogel, Andrew E. Rasmussen, Angelique O. J. Cramer
FRONTIERS IN PSYCHOLOGY
(2015)
Article
Psychology, Clinical
Andrew Rasmussen, Jay Verkuilen, Emily Ho, Yuyu Fan
PSYCHOLOGICAL ASSESSMENT
(2015)
Article
Anthropology
Andrew Rasmussen, Eddy Eustache, Giuseppe Raviola, Bonnie Kaiser, David J. Grelotti, Gary S. Belkin
TRANSCULTURAL PSYCHIATRY
(2015)
Article
Public, Environmental & Occupational Health
Tracy Chu, Allen S. Keller, Andrew Rasmussen
JOURNAL OF IMMIGRANT AND MINORITY HEALTH
(2013)
Article
Public, Environmental & Occupational Health
Andrew Rasmussen, Tracy Chu, Adeyinka M. Akinsulure-Smith, Eva Keatley
AMERICAN JOURNAL OF COMMUNITY PSYCHOLOGY
(2013)