Article
Ophthalmology
Morgan M. Harvey, Grant A. Justin, Daniel I. Brooks, Denise S. Ryan, Eric D. Weichel, Marcus H. Colyer
Summary: The study found that modern combat trauma results in complex ocular injuries, leaving 30% of patients legally blind in the injured eye. It is crucial to maintain a diverse range of deployable, specialty trained ophthalmologists to ensure optimal visual outcomes for wounded warriors, and maintain mission readiness.
OPHTHALMIC EPIDEMIOLOGY
(2021)
Article
Ophthalmology
Aaron M. Wold, Grant A. Justin, Samuel D. Hobbs, Katherine M. Baker, Derek P. Brady, James K. Aden, Denise S. Ryan, Eric D. Weichel, Marcus H. Colyer
Summary: This study characterized the nature of posterior segment ocular injuries in combat trauma, revealing that Zone II and III injuries were associated with worse visual prognosis. Closed-globe injuries showed lower risks of certain posterior segment injuries but higher risks of others compared to open-globe injuries.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Article
Clinical Neurology
Christine L. Mac Donald, Jason Barber, Jana Patterson, Ann M. Johnson, Carolyn Parsey, Beverly Scott, Jesse R. Fann, Nancy R. Temkin
Summary: This study compared 1-year and 5-year clinical outcomes in combat-deployed service members with and without brain injury, finding significant differences in neurobehavioral and psychiatric symptoms in patients with combat concussion over the long-term, with clinically significant decline observed. Even some of the control groups showed clinically significant decline, challenging the assumption that chronic stages of concussive injury are relatively stable.
Article
Ophthalmology
Justin P. Harris, Grant A. Justin, Daniel I. Brooks, Fasika A. Woreta, Rupesh V. Agrawal, Denise S. Ryan, Eric D. Weichel, Marcus H. Colyer
Summary: Open-globe injuries are common in combat ocular trauma, with poor final visual acuity noted most in corneo-scleral wounds, where approximately 50% of patients had a final visual acuity less than 20/200. Perforating and globe rupture injuries were found to be more likely to undergo enucleation.
ACTA OPHTHALMOLOGICA
(2021)
Article
Medicine, General & Internal
Madeline Romaniuk, Ying Xia, Gina Fisher, Kerstin Pannek, Jurgen Fripp, Justine Evans, Stephen Rose
Summary: This study compared grey matter volume and white matter microstructure among Australian combat veterans with and without a lifetime diagnosis of PTSD. The results showed significantly smaller grey matter volumes in the prefrontal cortex, middle frontal gyrus, and anterior insula in the PTSD group. In addition, negative correlations were found between PTSD symptom severity and fractional anisotropy values in specific white matter tracts. However, no connectome-based differences in white matter properties were observed.
MILITARY MEDICAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Kenric Tam, Jivianne T. Lee
Summary: This study investigates the prevalence of upper respiratory diseases in OEF/OIF veterans, revealing a significantly higher prevalence of both upper and lower respiratory diseases in these veterans compared to non-OEF/OIF veterans.
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2021)
Article
Engineering, Aerospace
Yongfeng Li, Yongxi Lyu, Jingping Shi, Weihua Li
Summary: This paper proposes an autonomous air combat maneuvering decision method based on the combination of simulated operation command and the final reward value deep deterministic policy gradient (FRV-DDPG) algorithm. The proposed method improves the autonomous air combat decision-making ability of UAVs by establishing a model and designing a prediction method.
Article
Clinical Neurology
Danielle D. Dang, Jason H. Boulter, Melissa R. Meister, John Dang, Geoffrey Ling, James Ecklund
Summary: NeuroTeam has played a crucial role in military medicine by providing world-class neurological care through collaboration with neurointensivists. Their innovations and adaptability have improved patient care and streamlined treatment processes on the battlefield.
NEUROSURGICAL FOCUS
(2022)
Article
Medicine, General & Internal
Sophie Richter, Stefan Winzeck, Evgenios N. Kornaropoulos, Tilak Das, Thijs Vande Vyvere, Jan Verheyden, Guy B. Williams, Marta M. Correia, David K. Menon, Virginia F. J. Newcombe
Summary: The study found that white matter injury is associated with symptoms after mild traumatic brain injury (mTBI), and performing imaging within 72 hours of injury can better predict clinical recovery. This could help in identifying high-risk patients for clinical follow-up or interventional trials.
Article
Public, Environmental & Occupational Health
Andrew J. MacGregor, James M. Zouris, Amber L. Dougherty, Judy L. Dye
Summary: The role of women in the United States military has expanded to include serving in all military occupations, including special operations and frontline combat units. However, combat-related injuries among military women can lead to adverse post-deployment health profiles, highlighting the need for further research on health outcomes and resource allocation.
WOMENS HEALTH ISSUES
(2021)
Article
Clinical Neurology
William C. Walker, Sarah W. Clark, Kaleb Eppich, Elisabeth A. Wilde, Aaron M. Martin, Chelsea M. Allen, Melissa M. Cortez, Mary Jo Pugh, Samuel R. Walton, Kimbra Kenney
Summary: This study analyzed the relationship between lifetime history of mild traumatic brain injury (mTBI) and other factors with headache prevalence and impact among combat-exposed current and former service members. The results showed that regardless of the remoteness of mTBI, participants with positive mTBI history had higher headache prevalence and impact. Blast-related mTBI posed the highest risk and was uniquely associated with elevated headache burden. Other demographic and potentially modifiable risk factors were also identified.
FRONTIERS IN NEUROLOGY
(2023)
Article
Immunology
Britahny M. Baskin, Aric F. Logsdon, Suhjung Janet Lee, Brian D. Foresi, Elaine Peskind, William A. Banks, David G. Cook, Abigail G. Schindler
Summary: In this study, repetitive blast trauma was induced in female and male mice using a blast overpressure model. The findings showed different behavioral, inflammatory, microbiome, and vascular dysfunction outcomes in female and male mice. However, only male mice exhibited adverse behavioral outcomes that lasted at least one month.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wenji Xu, Xiangru Sun, Haoru Jiang, Xiaochun Wang, Bin Wang, Qiao Niu, Huaxing Meng, Jiangfeng Du, Guoqiang Yang, Bo Liu, Hui Zhang, Yan Tan
Summary: This study investigates the use of diffusion kurtosis imaging (DKI) to differentiate mild cognitive impairment (MCI) from normal controls (NC) in aluminum (Al)-exposed workers, and explores the association between DKI, cognitive performance, and plasma Al concentration. The results indicate that DKI can be a sensitive imaging biomarker for diagnosing MCI and assessing the severity of cognitive impairment. The right hippocampus shows the most significant correlation with cognitive performance. However, there is no correlation between DKI parameters and plasma Al levels.
ACADEMIC RADIOLOGY
(2023)
Article
Neurosciences
Yuwen Hung, Marlee Vandewouw, Zahra Emami, Sonya Bells, Nicole Rudberg, Leodante da Costa, Benjamin T. Dunkley
Summary: Using multi-modality imaging methods, this study found disruptions in brain-behavior interactions related to working memory in patients with mild traumatic brain injury (mTBI), particularly in the hippocampal-prefrontal and amygdala circuits. These disruptions may leave mTBI patients vulnerable to increased environmental demands exerting memory resources, leading to cognitive and emotional psychopathologies.
HUMAN BRAIN MAPPING
(2022)
Article
Psychology, Clinical
Anna S. Ord, Erica L. Epstein, Elizabeth R. Shull, Katherine H. Taber, Sarah L. Martindale, Jared A. Rowland
Summary: Veterans who have recovered from PTSD show improvements in psychological symptoms, sleep quality, pain interference, and quality of life. However, cognitive functioning does not significantly differ between those who have recovered from PTSD and those who have not. History of deployment mTBI moderates the relationship between PTSD recovery and processing speed cognitive functioning.
REHABILITATION PSYCHOLOGY
(2022)
Meeting Abstract
Gastroenterology & Hepatology
Sayak Ghatak, Amy LaLonde, Tanya Malhotra, Liana Toia, Derick Peterson, Tony E. Godfrey, Joseph Wizorek, Christian Peyre, Carolyn Jones, Eileen Redmond, Jeffrey Peters
Meeting Abstract
Oncology
Michael Brady, Myla S. Strawderman, Christopher Flowers, Brad S. Kahl, John Paul Leonard, Loretta J. Nastoupil, Thomas E. Witzig, Derick R. Peterson, Jonathan W. Friedberg
JOURNAL OF CLINICAL ONCOLOGY
(2018)
Article
Neurosciences
Talia M. Nir, Neda Jahanshad, Christopher R. K. Ching, Ronald A. Cohen, Jaroslaw Harezlak, Giovanni Schifitto, Hei Y. Lam, Xue Hua, Jianhui Zhong, Tong Zhu, Michael J. Taylor, Thomas B. Campbell, Eric S. Daar, Elyse J. Singer, Jeffry R. Alger, Paul M. Thompson, Bradford A. Navia
JOURNAL OF NEUROVIROLOGY
(2019)
Retraction
Oncology
Girija Dasmahapatra, Dmitry Lembersky, Minkyeong P. Son, Hiral Patel, Derick Peterson, Elisa Attkisson, Richard I. Fisher, Jonathan W. Friedberg, Paul Dent, Steven Grant
MOLECULAR CANCER THERAPEUTICS
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Lan Lu, Yong Chen, Colette Shen, Jun Lian, Shiva Das, Lawrence Marks, Weili Lin, Tong Zhu
Article
Computer Science, Artificial Intelligence
Xuanang Xu, Chunfeng Lian, Shuai Wang, Tong Zhu, Ronald C. Chen, Andrew Z. Wang, Trevor J. Royce, Pew-Thian Yap, Dinggang Shen, Jun Lian
Summary: The study proposed an asymmetric multi-task attention network (AMTA-Net) for the concurrent segmentation of the prostate bed and surrounding organs-at-risk, demonstrating superior performance. By leveraging the critical dependency of the prostate bed on neighboring organs, the network achieved enhanced segmentation accuracy.
MEDICAL IMAGE ANALYSIS
(2021)
Article
Biology
Gregory Szalkowski, Dong Nie, Tong Zhu, Pew-Thian Yap, Jun Lian
Summary: The study uses machine learning to create synthetic CTs from pelvic MR images, providing proof of concept for accurate dose calculation and fiducial visualization.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Yong Chen, Lan Lu, Tong Zhu, Dan Ma
Summary: Magnetic resonance fingerprinting (MRF) is an emerging imaging technique that allows for rapid and simultaneous quantification of multiple tissue properties, potentially improving radiotherapy workflow and clinical decision making.
Article
Oncology
David Fried, Tong Zhu, Shiva K. Das, Colette Shen, Lawrence B. Marks, Xianming Tan, Bhishamjit S. Chera
Summary: This study assessed the impact of prospectively sparing the parotid ducts via MRI sialography on patient-reported xerostomia in oropharyngeal squamous cell carcinoma patients receiving radiotherapy. The results showed a significant reduction in xerostomia rates in the group with parotid duct sparing, and parotid duct dose was found to be associated with the severity of xerostomia.
RADIOTHERAPY AND ONCOLOGY
(2022)
Article
Nutrition & Dietetics
Janine Cubello, Derick R. Peterson, Lu Wang, Margot Mayer-Proschel
Summary: Maternal iron deficiency and environmental lead exposure both impact the neurodevelopment of offspring. This study demonstrated that iron deficiency leads to iron depletion in specific brain regions, which is exacerbated by lead exposure. Moreover, blood lead levels may not accurately reflect the lead burden in the brain, especially in the presence of iron deficiency.
Meeting Abstract
Oncology
D. V. Fried, T. Zhu, S. K. Das, C. Shen, K. A. Pearlstein, L. B. Marks, B. S. Chera
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2021)
Article
Medicine, Research & Experimental
Kristin M. Scheible, Jason Emo, Nathan Laniewski, Andrea M. Baran, Derick R. Peterson, Jeanne Holden-Wiltse, Sanjukta Bandyopadhyay, Andrew G. Straw, Heidie Huyck, John M. Ashton, Kelly Schooping Tripi, Karan Arul, Elizabeth Werner, Tanya Scalise, Deanna Maffett, Mary Caserta, Rita M. Ryan, Anne Marie Reynolds, Clement L. Ren, David J. Topham, Thomas J. Mariani, Gloria S. Pryhuber
Meeting Abstract
Cardiac & Cardiovascular Systems
Meng Wang, Scott McNitt, Derick Peterson, David Q. Rich, Christopher L. Seplaki, Ilan Goldenberg, Valentina Kutyifa, Alon Barsheshet, Arthur J. Moss, Wojciech Zareba
Meeting Abstract
Hematology
Alok A. Khorana, Nigel Mackman, Yohei Hisada, Cihan Ay, Derick Peterson, Charles W. Francis, Andrea Baran
Meeting Abstract
Critical Care Medicine
S. Bhattacharya, J. Mereness, A. Baran, R. S. Misra, C. Slaunwhite, H. Huyck, S. Bandyopadhyay, J. Holden-Wiltse, D. R. Peterson, R. M. Ryan, A. -M. Reynolds, G. S. Pryhuber, T. J. Mariani
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2017)