期刊
JOURNAL OF HAND THERAPY
卷 22, 期 2, 页码 109-113出版社
HANLEY & BELFUS-ELSEVIER INC
DOI: 10.1016/j.jht.2008.10.008
关键词
-
资金
- Intramural Research Program of the NIH, NINDS
Narrative Review: Focal hand dystonia is a disabling movement disorder, often task specific, that leads to impaired hand use. In addition to a genetic predisposition, environmental risk factors including repetitive use and musculoskeletal constraints are contributory. Although the underlying cause is unknown, recent studies have identified several key mechanisms that may play a part in its genesis. Failure of inhibition, abnormal sensorimotor integration, and maladaptive plasticity seen to be important. Understanding the underlying physiology may lead to the design of novel therapies. Level of Evidence: 5. I HAND THER. 2009;22:109-14.
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