Article
Multidisciplinary Sciences
Sylwia M. Kolenderska, Maciej Szkulmowski
Summary: Quantum Optical Coherence Tomography (Q-OCT) offers high resolution and immunity to dispersion, but suffers from artifacts. Two algorithms are proposed to address artifacts in Fd-Q-OCT, despite effective methods already existing in Time-domain Q-OCT.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Abigail J. Deloria, Sandra Haider, Bianca Dietrich, Victoria Kunihs, Simon Oberhofer, Martin Knofler, Rainer Leitgeb, Mengyang Liu, Wolfgang Drexler, Richard Haindl
Summary: The study demonstrates the use of 3D optical coherence tomography (OCT) for analyzing human placenta organoids without sample preparation. Results show that 3D OCT enables detailed monitoring of placenta organoids, visualizing and quantifying internal structures in situ to assess differentiation status and aid advancement in the field.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Engineering, Electrical & Electronic
Chengang Lyu, Jiachen Tian, Bo Yang, Yi Deng, Yanping Xiao, Jie Jin, Chunfeng Ge
Summary: A method for simultaneous measurement of static strain and dynamic vibration with high spatial resolution based on millimeter sized ultra-short fiber Bragg grating is proposed in this paper. The measurement is achieved by interrogating cascaded FBGs with optical coherence tomography method using a designed wavelength swept light source. The experiments demonstrate that the proposed method can accurately measure both strain and vibration parameters with high sensitivity and spatial resolution, showing great application potential in the field of mechanical sensing.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2022)
Article
Medicine, General & Internal
Lisa Toto, Maria Ludovica Ruggeri, Federica Evangelista, Chiara Trivigno, Rossella D'Aloisio, Chiara De Nicola, Pasquale Viggiano, Emanuele Doronzo, Marta Di Nicola, Annamaria Porreca, Rodolfo Mastropasqua
Summary: This study investigates the parameters of optical coherence tomography (OCT) and OCT angiography (OCTA) in patients with neovascular age-related macular degeneration (nAMD) and macular neovascularization (MNV) types 1, 2, and 3. The results showed significant differences in CVI, CMT, and ORCCFA between MNV 1 and the other two groups. CVI was significantly different between MNV 1 and healthy controls and between MNV 1 and MNV 2. ORCCFA and CMT were significantly different between MNV 1 and MNV 2. There was no statistically significant difference in subfoveal choroidal thickness (SFCT) among the three groups.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Optics
Manuel J. Marques, Ramona Cernat, Jason Ensher, Adrian Bradu, Adrian Podoleanu
Summary: This paper presents a different approach for processing interferometer signals driven by swept sources with non-linear tuning, evaluating the suitability of the Master-Slave (MS) procedure for such sources. The Master-Slave process is applied to intact interferogram spectrum delivered by an OCT system, allowing near-coherence-limited operation at a large axial range. Depth information can be recovered with some limitations in both cases.
Article
Optics
Manabu Sato, Shunta Nakabayashi, Ryusei Ito, Junpei Masuta, Tetsuo Kosaka
Summary: A method utilizing sub-bins and the inverse matrix to reduce spectral leakage in discrete Fourier transform (DFT) and improve frequency resolution is proposed and experimentally confirmed.
Article
Engineering, Electrical & Electronic
Xin Ge, Shufen Chen, Si Chen, Linbo Liu
Summary: High resolution optical coherence tomography (HR-OCT) has made significant progress in imaging cellular and extracellular structures, with broad clinical applications. This review focuses on the latest advancements in technology development and clinical research using this powerful imaging tool, promoting interdisciplinary research.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2021)
Article
Computer Science, Information Systems
Huaying Hao, Cong Xu, Dan Zhang, Qifeng Yan, Jiong Zhang, Yue Liu, Yitian Zhao
Summary: This paper proposes a Sparse-based domain Adaptation Super-Resolution network (SASR) for the reconstruction of low-resolution OCTA images to high-resolution representations. By using registration and generative-adversarial strategy, the synthetic and realistic LR images are unified in the feature domain, resulting in more accurate results.
IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS
(2022)
Article
Pharmacology & Pharmacy
Matthias Wolfgang, Alice Kern, Shiyu Deng, Sandra Stranzinger, Mengyang Liu, Wolfgang Drexler, Rainer Leitgeb, Richard Haindl
Summary: Optical Coherence Tomography (OCT) has gained attention as a promising technology for monitoring pharmaceutical film-coating processes and end-point detection. We present an ultra-high-resolution (UHR-) OCT and demonstrate its performance on different multiparticulate dosage forms with different layer structures. The achieved system resolution enables the assessment of defects, film thickness variability, and morphological features within the coating.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Optics
Reddikumar Maddipatla, Patrice Tankam
Summary: Combining optical coherence microscopy with fluorescence microscopy allows for the alignment of structural and functional information, enabling new investigations into biological processes in animal models.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Optics
Chaoliang Chen, Yurui Pu, Weisong Shi
Summary: In this study, a low-cost, high-resolution spectrometer design for ultra-high resolution optical coherence tomography (UHR-OCT) is presented, in which multiple standard achromatic lenses are used to replace the expensive F-theta lens. The proposed method achieves comparable performance and reduces the cost significantly.
CHINESE OPTICS LETTERS
(2023)
Article
Optics
M. A. Volynsky, E. S. Gladkova, I. P. Gurov, E. Zhukova, N. B. Margaryants, S. Sirro, P. S. Skakov
Summary: The article discusses the peculiarities of using optical coherence tomography to examine valuable paintings and presents a full-field optoelectronic system for determining the internal microstructure of inhomogeneous media with high resolution. Examples are provided to show how this technology can be used to determine specific features of the microstructure of antique easel tempera paintings.
JOURNAL OF OPTICAL TECHNOLOGY
(2021)
Article
Multidisciplinary Sciences
Ziv Lautman, Yonatan Winetraub, Eran Blacher, Caroline Yu, Itamar Terem, Adelaida Chibukhchyan, James H. Marshel, Adam de la Zerda
Summary: Optical coherence tomography (OCT) allows label-free, micron-scale 3D imaging of biological tissues' fine structures with significant depth and large field-of-view. A novel OCT-based neuroimaging setting, accompanied by a feature segmentation algorithm, enables rapid, accurate, and high-resolution in vivo imaging of 700 mu m depth across the mouse cortex. This highly transformative and versatile platform allows accurate investigation of brain cellular architectural changes by quantifying features such as brain cell bodies' density, volume, and average distance to the nearest cell, and may assist in longitudinal studies of microstructural tissue alteration in aging, injury, or disease in a living rodent brain.
SCIENTIFIC REPORTS
(2022)
Article
Biochemical Research Methods
Clayton B. Walker, Anna Wisniowiecki, Jack C. Tang, Patricia M. Quinones, Wihan Kim, John S. Oghalai, Brian E. Applegate
Summary: This paper presents a processing approach for optical coherence tomography (OCT) based on a multi-window method, which improves resolution and suppresses side-lobe intensity. By selecting appropriate window functions, the approach achieves better performance for phase-sensitive applications.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Ophthalmology
Vasilios P. Papastefanou, Rana'a T. Al-Jamal, Zaria Christine Ali, Victoria M. L. Cohen, Jane Gray, Mandeep S. Sagoo, Konstantinos Balaskas
Summary: The study found that the use of ultra-wide-field imaging with red-green channels has limitations in the diagnosis of small choroidal melanoma and is not reliable for early detection. Melanotic naevi and small melanomas exhibit distinct features in red-green channel imaging, which may help predict disease progression and prognosis.
Article
Instruments & Instrumentation
D. Thickett, C. S. Cheung, H. Liang, J. Twydle, R. Gr Maev, D. Gavrilov
Article
Optics
Haida Liang, Meropi Mari, Chi Shing Cheung, Sotiria Kogou, Phillip Johnson, George Filippidis
Article
Humanities, Multidisciplinary
Suzanne Wijsman, Sarah Neate, Sotiria Kogou, Haida Liang
Article
Multidisciplinary Sciences
Pauline Ogrodzki, Chi Shing Cheung, Mohamed Saad, Khaled Dahmani, Rebecca Coxill, Haida Liang, Stephen J. Forsythe
SCIENTIFIC REPORTS
(2017)
Article
Physics, Multidisciplinary
A. M. J. Edwards, P. S. Atkinson, C. S. Cheung, H. Liang, D. J. Fairhurst, F. F. Ouali
PHYSICAL REVIEW LETTERS
(2018)
Article
Optics
Yu Li, Shing Chi Cheung, Sotiria Kogou, Florence Liggins, Haida Liang
Article
Spectroscopy
Sotiria Kogou, Lynn Lee, Golnaz Shahtahmassebi, Haida Liang
Summary: The study applies the self-organising map algorithm to analyze XRF spectral imaging data, using clustering and a combination of spatial and spectral information to aid materials identification and deduce painting sequences. The efficiency and accuracy of the method are confirmed through analysis of the research object.
X-RAY SPECTROMETRY
(2021)
Article
Archaeology
Margaret Read, C. S. Cheung, Haida Liang, Andrew Meek, Capucine Korenberg
Summary: This study demonstrates the successful imaging of the full microstructure of Egyptian faience from the top glaze layer down to the core using a home-developed OCT system with a longer wavelength (2 µm), showing the potential for rapid and non-invasive studies of intact objects and surveying large museum collections. By comparing OCT virtual cross-section images at 5 wavelengths, the optimum wavelength for investigating Egyptian faience microstructure was found to be 2 µm.
STUDIES IN CONSERVATION
(2022)
Article
Physics, Multidisciplinary
Yu Li, Amelia Suzuki, Chi Shing Cheung, Yuda Gu, Sotiria Kogou, Haida Liang
Summary: Reflectance spectroscopy is more sensitive than Raman spectroscopy in detecting laser-induced degradation issues. Continuous-wave (CW) lasers are found to be the best choice for efficient and safe Raman operation.
EUROPEAN PHYSICAL JOURNAL PLUS
(2022)
Article
Physics, Multidisciplinary
Mixon K. Faluweki, C. S. Cheung, Haida Liang
Summary: A novel technique using optical coherence tomography (OCT) for simultaneous measurement of refractive index and dispersion of transparent solid materials is described. The technique requires multi-angle OCT imaging and provides high precision measurements. This method can be applied to the restoration of modern sculptures made from plastics, where accurate measurement of refractive index is crucial for finding a matching resin adhesive to restore damaged artworks.
EUROPEAN PHYSICAL JOURNAL PLUS
(2023)