期刊
JOURNAL OF GENETICS AND GENOMICS
卷 37, 期 2, 页码 125-135出版社
SCIENCE PRESS
DOI: 10.1016/S1673-8527(09)60031-X
关键词
domesticated silkworm; SINE; distribution; structural variant
资金
- Natural Science Foundation [2009BB1241]
- Ministry of Science and Technology of China [2006AA10A117, 2005CB121003]
Short interspersed elements (SINEs), which are mainly composed of Bm1, are abundant in the domesticated silkwonn. A 294 bp novel SINE family, designated as BmSE, was identified by mining the database of the complete Bombyx mori genome. A representational BmSE element is flanked by an I I bp target site duplication sequence posterior poly (A) at the 3' end and has the sequence motifs of an internal promoter of RNA polymerase 111, which are similar to that of Bm1. The repetitive elements of BmSE are widely distributed in all 28 chromosomes of the genome and share the common (ATTT) repeats at the ends. GC-content distribution shows that BmSE tends to accumulate preferably in the region of higher AT content than that of Bm1. A high proportion of the BmSEs are mapped to the coding sequence introns, whereas several elements are also present in the UTR of some transcripts, indicating that BmSEs are indeed exonized with UTRs. Of the 615 identified structural variants (SVs) of BmSE among the 40 domesticated and wild silkworms, only 230 SVs were found in the domesticated silkworms, indicating that many recent SV events of BmSE occurred after domestication, which was probably due to its mobilization. Our analysis might assist in developing BmSE as a potential marker and in understanding the evolutionary roles of SINEs in the domesticated silkwonn.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据